<strong>Road</strong> <strong>to</strong> <strong>Emmaus</strong> Vol. XIII, <strong>No</strong>. 2 (#49)Natural Conception, Natural BirthRtE: <strong>No</strong>t <strong>to</strong> mention that in IVF the lab techs are making the choice as <strong>to</strong>which eggs and sperm <strong>to</strong> incubate rather than letting God’s providence andthe body do so.Melanie: Yes, in IVF they harvest what they think are the most mobile,regular-looking sperm, but we know so little about the intricacies of conceptionthat it might actually be the sperm with the irregular head shape whoare naturally fertilizing the eggs. We don’t know anything for sure. Mobilityand regularity as a guide <strong>to</strong> health is just a best guess.Also, in regard <strong>to</strong> ovulation, at any given time in a woman’s fertile periodthere are several possible follicles with eggs. We don’t know how or why thebody chooses that one mature egg <strong>to</strong> ripen in<strong>to</strong> a follicle and then burst andovulate. It’s a complicated process that we simply don’t understand. Whenyou artificially hyper-stimulate the ovaries <strong>to</strong> release more eggs, rather thanone mature follicle bursting and one egg ovulating, that one ovary may haveten mature follicles that you then harvest out while the woman is sedated.We don’t have enough reliable data <strong>to</strong> say that this is safe, so this is a sub-parresult for the woman and, because of the risks for children born through IVF,a sub-par result for the child.IVF and IUI are simply imperfect: we can’t replicate what nature doesthrough the cervical fluid, through the contractions of the Fallopian tube,through the prostaglandins—it’s a very complicated process. <strong>No</strong>r havewe been able <strong>to</strong> perfectly replicate the way the sperm meets the egg andbreaks through the shell, which is extremely complex. <strong>No</strong>w scientistsare wondering if there is some sort of reaction between the enzymes onthe sperm and the cervical fluid that allows for conception in a way thatproduces a healthier child.Also, under a microscope, the cervical fluid looks like perfect little channelsor superhighways. With natural conception, the sperm travel thesehighways <strong>to</strong> make it through the cervix and in<strong>to</strong> the Fallopian tube <strong>to</strong> meetthe egg. When the estrogen drops sharply after ovulation, the hormonethat takes over is progesterone, which is responsible for the build-up of theuterine tissue. <strong>No</strong>w, instead of the perfect little highways, the cervical fluidlooks like a brick wall. The sperm can’t penetrate because this is the body’snatural way of making sure that sperm will not meet an egg that is not fresh.Both vitro fertilization and intrauterine insemination bypass this naturalsafeguard.<strong>No</strong>r do we completely understand how the fertilized egg manages <strong>to</strong> reachthe Fallopian tube. Even if one Fallopian tube is damaged and a womanovulates from the ovary on that side, the egg can somehow find its wayover <strong>to</strong> the Fallopian tube on the undamaged side. The human body knowsinfinitely more than we could ever see in a labora<strong>to</strong>ry with the best scientistsin the world.RtE: When you read about conception, and the incredible odds against asingle sperm and egg meeting, it seems very providential.Melanie: Yes, it appears that less than ten sperm out of millions make itthrough the cervix in<strong>to</strong> the Fallopian tube, and only one of them is waiting<strong>to</strong> meet the egg.To <strong>to</strong>uch on the spiritual angle, I like the way that the Orthodox bioethicist,Metropolitan Nikolaos (Hatzinikolaou) of Mesogaia and Lavreotiki speaksabout conception. He says that it is very disturbing <strong>to</strong> take the creation of lifeout of the warmth of the marital bed and place it in the coldness of a labora<strong>to</strong>rypetri dish. 2 This resonates with all of us; it’s unnatural <strong>to</strong> introduce athird party in<strong>to</strong> the reproductive act.RtE: In IVF, do they implant one or many fertilized eggs?Melanie: Typically because it is so expensive (about $12,000 - $17,000 pertry depending on where you live) more than one embryo is implanted <strong>to</strong> insuresuccess. It is normal <strong>to</strong> implant four <strong>to</strong> six.RtE: This is why we hear of women who have used fertility drugs or IVF havingmultiple children. What if all of the embryos implant?Melanie: Then they will urge selective abortion. A recent dramatic exampleof this is the well-known American “Octamom” who had eight healthyembryos that survived the initial implantation. When they asked her <strong>to</strong>selectively abort most of the babies, she refused. If you have been waitingfor a child and someone tells you that the best chance is this very healthylookingegg that has just been implanted, you will tend <strong>to</strong> believe them.2 “The Embryo and its Development in Regard <strong>to</strong> its Formation as a Complete Human Being”, Conference onthe Church and Bioethics: The Word of Science and the Word of Religion, Chambésy, France, 11-15 September<strong>20</strong>02. Available online at: http://www.bioethics.org.gr/en/index.htmlA more recent article, “The Greek Orthodox Position on the Ethics of Assisted Reproduction” can beviewed at http://www.bioethics.org.gr/MMLN%<strong>20</strong>assisted%<strong>20</strong>repro.pdf1011
<strong>Road</strong> <strong>to</strong> <strong>Emmaus</strong> Vol. XIII, <strong>No</strong>. 2 (#49)Natural Conception, Natural BirthThe clinic then expects you <strong>to</strong> go through a routine selective abortion, whichthey term “reduction”. Left-over fertilized embryos in the petri dish that are notimplanted are either discarded or frozen. If you create an excess of embryos,what happens if the woman feels she can’t have more children or doesn’thave the funds <strong>to</strong> go through another round of implantation? <strong>No</strong>w youessentially have frozen children that are just left waiting.RtE: How long do they keep these embryos?Melanie: It depends. The labs only s<strong>to</strong>re them for so long, because eventuallythey will become <strong>to</strong>o old <strong>to</strong> be implanted. One of the issues that theCatholic Church is now dealing with is whether there should be embryoadoption—there are Catholic women who are offering <strong>to</strong> take these frozenembryos and carry them <strong>to</strong> birth, in order <strong>to</strong> save these lives.RtE: To add <strong>to</strong> the dilemma, in her talk at the <strong>No</strong>vember, <strong>20</strong>11 OrthodoxChristian Association of Medicine, Psychology and Religion (OCAMPR) Conferenceon “The Science and Theology of Conception”, Dr. Gayle Woloschak,an Orthodox professor from the Center for Genetic Medicine at <strong>No</strong>rthwesternUniversity, mentioned that even in good labs with careful scientists andback-up refrigeration systems, occasionally the entire system shuts down.It’s not really possible <strong>to</strong> guarantee that the frozen embryos will be kept safe.Melanie: I would also like <strong>to</strong> hear more about the defects of children bornof IVF. Some advocates of IVF claim that the defects aren’t serious, whenactually they are. One study focuses on children born with Beckwith-WiedemannSyndrome, a gene alteration characterized by a 15% risk of childhoodcancers of the kidney, liver or muscles and an overgrowth of cells of the kidneyand other tissues. Other possible abnormalities include a large <strong>to</strong>ngue,abdominal wall defects, and low levels of blood-sugar in infancy. 3RtE: So they are saying that approximately 15% of the children with thissyndrome will develop childhood cancer?Melanie: Yes. The normal risk of childhood cancer, by the way, is less thanone in 10,000. <strong>No</strong>w the interesting thing was that there were so many mothersin this study whose children had been born via IVF that they decidedamong themselves <strong>to</strong> ask the researchers if there was a connection. Theirquestion launched a reassessment of over half a dozen large studies that concludedthat it was ten times more likely that parents who had used IVF orrelated methods would see this syndrome in their children.Another aberration that has been detected is the Angelman Syndrome,which involves severe mental retardation, mo<strong>to</strong>r defects, an inability <strong>to</strong>speak, but accompanied thankfully by a cheerful disposition. Researchershave begun <strong>to</strong> believe that your chance of having either syndrome is exponentiallymuch greater if you use IVF.Also, meta-analyses of many individual studies reveal that IVF recipientshave significantly higher rates for stillbirths, premature births, gestationaldiabetes, preeclampsia, placenta previa, vaginal bleeding, cesarean sections,and so on. 4 This shows that not only the infant’s health is compromised,but the mother’s as well. A natural conception in the body is the far moreloving option.RtE: I suppose that people might answer that by asking, “Well, you tell usthat life on any terms is better than aborting a child. Why wouldn’t conceivinga child through IVF be better than no life at all, even if there are theserisks?” The problem is not the desire for the child, but that we are manipulatingthe natural process and not leaving it up <strong>to</strong> God’s providence. We alsoknow there are many children needing adoption. Do you have any idea ofhow many people were involved with IVF last year?Melanie: In 1996, there were 50,000 IVF attempts in the U.S. By <strong>20</strong>02 itwas 100,000 per year and it is undoubtedly much higher now. The internetsite www.ivf.net claims that 3 million IVF babies have been born worldwide.If this is true, many more couples have tried.RtE: What is the rate of IVF success?Melanie: On average, about 30%. Many of our Creigh<strong>to</strong>n Method doc<strong>to</strong>rstake women who have had failed IVF attempts. Our success rate is as high as30% for these women who have previously failed with IVF.RtE: This all sounds like a horror movie. It’s so beyond anything we dream<strong>to</strong>f a few decades ago.3 “The Risk of Major Birth Defects after Itracy<strong>to</strong>plasmic Sperm Injection and In Vitro Fertilization”, The NewEngland <strong>Journal</strong> of Medicine, Vol. 346, #10, March 7, <strong>20</strong>02, pgs. 725-730.4 “Perinatal Outcomes in Single<strong>to</strong>ns Following In Vitro Fertilization: A Meta-Analysis” The American <strong>Journal</strong>of Obstetricians and Gynecologists, March <strong>20</strong>04, 103 (3): 551-63.1213
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