References 1. Assayag, M. S., J. L. V. Chacon, and A. P. Ferreira. Economic impact of infectious bronchitis in a poultry integration system. In: M. Lierz, U. Heffels-Redmann, and E. F. Kaleta (eds.), VII <strong>International</strong> Symposium on Avian Corona- and Pneumoviruses and Complicating Pathogens, pp. 80-83. Rauischholzhausen, Germany; 2012. 2. Assayag, M. S., P. T. Rocha, A. C. Pedroso, and C. E. Pereira. Epidemiology of IB and the impact in the condemnations in the slaughterhouse. In: M. Lierz, U. Heffels-Redmann, and E. F. Kaleta (eds.), VII <strong>International</strong> Symposium on Avian Corona- and Pneumoviruses and Complicating Pathogens, pp. 74-79. Rauischholzhausen, Germany; 2012. 3. Enjuanes, L., D. Brian, D. Cavanagh, K. Holmes, M. M. C. Lai, H. Laude, P. Masters, P. Rottier, S. G. Siddell, W. J. M. Spaan, F. Taguchi, and P. Talbot. Coronaviridae. In: Virus taxonomy. Classification and nomenclature of viruses. M. H. V. van Regenmortel, C. M. Fauquet, D. H. L. Bishop, E. B. Carstens, M. K. Estes, S. Lemon, J. Maniloff, M. Mayo, D. J. McGeoch, C. R. Pringle, and R. B. Wickner, eds. Academic Press, New York, N.Y. pp 835-849. 2000. 4. Enjuanes, L., W. J. Spaan, E. J. Snijder, and D. Cavanagh. Nidovirales. In: Virus taxonomy. Classification and nomenclature of viruses M. H. V. v. Regenmortel, C. M. Fauquet, D. H. L. Bishop, E. B. Carsten, M. K. Estes, S. M. Lemon, D. J. McGeoch, J. Maniloff, M. A. Mayo, C. R. Pringle, and R. B. Wickner, eds. Academic Press, New York, N.Y. pp 827–834. 2000. 5. Eyigor, A., S. Kahya, F. Coven, S. Temelli, and K. T. Carli. Detection of IS/1494/06 - like vian infectiousbronchitis virus from chickens in Turkey. In: M. Lierz, U. Heffels- Redmann, nd D. Enderlein (eds.),8th Syposium on ACOV & AMPV, pp. 20-22. Rauischholzhausen, Germany: VVB Laufersweiler Verlag, Germany; 2014. 6. Gallardo, R. A., V. L. van Santen, and H. Toro. Effects of chicken anemia virus and enfectious bursal disease virus-induced immunodeficiency on infectious bronchitis virus eplication and genotypic drift. Avian Pathol. 41:451-458. 2012. 7. Gallardo, R. A., V. L. van Santen, and H. Toro. Host intraspatial selection of infectious bronchitis virus populations. Avian Dis. 54:807-813. 2010. 8. Jungherr, E. I., T. W. Chomiak, and R. E. Luginbuhl. Immunologic differences in strains of infectious bronchitis virus. In: Proceedings 60th Annual Meeting U.S. Livestock Sanitary Association:203-209. 1956. 9. Lai, M. M. C., and D. Cavanagh. The molecular biology of coronaviruses. Adv. Vir. Res. 8:1-100. 1997. 10. McKinley, E. T., D. A. Hilt, and M. W. Jackwood. Avian coronavirus infectious bronchitis attenuated live vaccines undergo selection of subpopulations and mutations following accination. Vaccine 26:1274-1284. 2008. 11. Ndegwa, E. N., K. S. Joiner, H. Toro, F. W. van Ginkel, and V. L. van Santen. The proportion of specificviral subpopulations in attenuated ArkDPI infectious bronchitis vaccines influences vaccination outcome. Avian Dis. 56:642-653. 2012. 12. Schalk, A. F., and M. C. Hawn. An apparently new respiratory disease of baby chicks. J. Am. Vet. Med. Assoc. 78:413-422. 1931. 13. Stadler, K., V. Masignani, M. Eickmann, S. Becker, S. Abrignani, H.-D. Klenk, and R. Rappuoli. Comparison of coronavirus genome structures. Nature Rev. Microbiol. 1:209- 218. 003. 14. Toro, H., J. W. Jackwood, and V. L. van Santen. Genetic diversity and selection regulates evolution of infectious bronchitis virus Avian Dis. 56:449-455. 2012. 166
O 46 Intestinal Microbiome of Broilers and It’s Interaction with Health and Disease Status of the Host K. Serdar Diker, İnci Başak Kaya Ankara University, Faculty of Veterinary Medicine, Ankara, Turkey Abstract In Turkey, Salmonella infections are the most observed infections of poultry industry and also it is the most important disease fort the public health and economical loss. Antibiotic usage is the most important treatment method for struggling the disease. Nevertheless the bacterial resistance to antibiotics leads to alternative treatment regimens. Considering the relations between microorganisms recently the most attractive word microbiome seems to gets importance. The technological improvements in biological areas leads to performing laborious metagenomic analysis in very short time with a little cost and high accuracy. With this extent the new sequencing systems help us to correlate microbial spectrum between animals and humans and also between the diseases. Also with these systems there is no need to make any amplifications and conventional culture techniques for determining the microorganismal taxon. This feature gives us the opportunity for determining the microbiome of animal, human, food and environment. With the known microbiota the colonization of bacteria such as Salmonella and Clostridium perfringens in poultry could be inhibited and the need to antibiotic usage would be decreased. 167
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