PCT/2001/21 : PCT Gazette, Weekly Issue No. 21, 2001 - WIPO

21/2001
8704 PCT Gazette - Section I - Gazette du PCT 25 May/mai 2001
SK SL TJ TM TR TT TZ UA UG US UZ VN
YU ZA ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI
FR GB GR IE IT LU MC NL PT SE TR); OA
(BF BJ CF CG CI CM GA GN GW ML MR
NE SN TD TG).
Published / Publiée :(c)
(51) 7 C07D 473/30, A61K 31/522, A61P 25/28
(11) WO 01/36419 (13) A1
(21) PCT/US00/41645
(22) 27 Oct/oct 2000 (27.10.2000)
(25) en (26) en
(30) 09/442,151 16 Nov/nov 1999 US
(16.11.1999)
(43) 25 May/mai 2001 (25.05.2001)
(54) • USE OF 9-SUBSTITUTED HYPOXAN-
THINE DERIVATIVES TO STIMULATE
REGENERATION OF NERVOUS TIS-
SUE
• UTILISATION DE DERIVES D’HY-
POXANTHINE 9-SUBSTITUEE AFIN
DE STIMULER LA REGENERATION
DES TISSUS NERVEUX
(71) NEOTHERAPEUTICS, INC. [US/US];
157 Technology Drive, Irvine, CA 92618
(US).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) GLASKY, Alvin [US/US]; 11955 Lambert,
Tustin, CA (US).
(74) CULLMAN, Louis, C.; Oppenheimer Wolff
& Donnelly LLP, 2029 Century Park East,
Suite 3800, Los Angeles, CA 90067-3024
(US).
(81) AE AG AL AM AT AU AZ BA BB BG BR
BY BZ CA CH CN CR CU CZ DE DK DM
DZ EE ES FI GB GD GE GH GM HR HU
ID IL IN IS JP KE KG KP KR KZ LC LK
LR LS LT LU LV MA MD MG MK MN MW
MX MZ NO NZ PL PT RO RU SD SE SG SI
SK SL TJ TM TR TT TZ UA UG US UZ VN
YU ZA ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI FR
GB GR IE IT LU MC NL PT SE); OA (BF BJ
CF CG CI CM GA GN GW ML MR NE SN
TD TG).
Published / Publiée :(c)
(51) 7 C07D 487/04, A61K 31/5025, 31/4985,
A61P 43/00, 9/02, 11/00, 17/02, 11/06,
27/16, 37/08, 29/00, 19/02, 9/10, 1/04, 17/06,
9/04
(11) WO 01/36420
(21) PCT/JP00/07907
(13) A1
(22) 10 Nov/nov 2000 (10.11.2000)
(25) ja (26) ja
(30) 11/323884 15 Nov/nov 1999
(15.11.1999)
JP
(43) 25 May/mai 2001 (25.05.2001)
(54) • TRICYCLIC AZAINDOLIZINE
DERIVATIVES HAVING AN SPLA2-
INHIBITING EFFECT
• DERIVES D’AZA-INDOLIZINE TRI-
CYCLIQUE AYANT UN EFFET INHI-
BITEUR SUR SPLA2
(71) SHIONOGI & CO., LTD. [JP/JP]; 1-8,
Doshomachi 3-chome, Chuo-ku, Osaka-shi,
Osaka 541-0045 (JP).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) FUJI, Masahiro [JP/JP]; Shionogi
& Co., Ltd., 12-4, Sagisu 5-chome,
Fukushima-ku, Osaka-shi, Osaka 553-0002
(JP). OKADA, Tetsuo [JP/JP]; Shionogi
& Co., Ltd., 12-4, Sagisu 5-chome,
Fukushima-ku, Osaka-shi, Osaka 553-0002
(JP). ADACHI, Makoto [JP/JP]; Shionogi
& Co., Ltd., 12-4, Sagisu 5-chome,
Fukushima-ku, Osaka-shi, Osaka 553-0002
(JP).
(74) YAMAUCHI, Hideaki et al. / etc.; Shionogi
& Co., Ltd. Intellectual Property Dept., 12-4,
Sagisu 5-chome, Fukushima-ku, Osaka-shi,
Osaka 553-0002 (JP).
(81) AE AG AL AM AT AU AZ BA BB BG BR
BY BZ CA CH CN CR CU CZ DE DK DM
DZ EE ES FI GB GD GE GH GM HR HU ID
IL IN IS JP KE KG KR KZ LC LK LR LS LT
LU LV MA MD MG MK MN MW MX MZ
NO NZ PL PT RO RU SD SE SG SI SK SL
TJ TM TR TT TZ UA UG US UZ VN YU ZA
ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI
FR GB GR IE IT LU MC NL PT SE TR); OA
(BF BJ CF CG CI CM GA GN GW ML MR
NE SN TD TG).
(51) 7 C07D 487/04, A61K 31/519, A61P 7/02 //
(C07D 487/04, 249:00, 239:00)
(11) WO 01/36421 (13) A1
(21) PCT/SE00/02229
(22) 14 Nov/nov 2000 (14.11.2000)
(25) en (26) en
(30) 9904129-5 15 Nov/nov 1999 SE
(15.11.1999)
(43) 25 May/mai 2001 (25.05.2001)
(54) • NOVEL [1,2,3]-TRIAZOLO[4,5-
D]PYRIMIDINE COMPOUNDS
• COMPOSES A BASE DE [1,2,3]-TRIA-
ZOLO[4,5-D]PYRIMIDINE
(71) ASTRAZENECA AB [SE/SE]; S-151 85
Södertälje (SE).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) GUILE, Simon [GB/GB]; AstraZeneca
R & D Charnwood, Bakewell Road,
Loughborough, Leics. LE11 5RH (GB).
SPRINGTHORPE, Brian [GB/GB]; AstraZeneca
R & D Charnwood, Bakewell
Road, Loughborough, Leics. LE11 5RH
(GB).
(74) ASTRAZENECA AB; Global Intellectual
Property, S-151 85 Södertälje (SE).
(81) AE AG AL AM AT AU AZ BA BB BG BR
BY BZ CA CH CN CR CU CZ DE DK DM
DZ EE ES FI GB GD GE GH GM HR HU
ID IL IN IS JP KE KG KP KR KZ LC LK
LR LS LT LU LV MA MD MG MK MN MW
MX MZ NO NZ PL PT RO RU SD SE SG SI
SK SL TJ TM TR TT TZ UA UG US UZ VN
YU ZA ZW.
(84) AP (GH GM KE LS MW MZ SD SL SZ TZ
UG ZW); EA (AM AZ BY KG KZ MD RU
TJ TM); EP (AT BE CH CY DE DK ES FI
FR GB GR IE IT LU MC NL PT SE TR); OA
(BF BJ CF CG CI CM GA GN GW ML MR
NE SN TD TG).
(51) 7 C07D 487/04, 495/14, 491/14, A61K
31/505, A61P 9/12 // (C07D 487/04, 239:00,
231:00) (C07D 495/14, 335:00, 239:00,
231:00) (C07D 491/14, 307:00, 239:00,
231:00)
(11) WO 01/36422 (13) A1
(21) PCT/US00/32333
(22) 17 Nov/nov 2000 (17.11.2000)
(25) en (26) en
(30) 09/443,212 19 Nov/nov 1999 US
(19.11.1999)
(30) 09/709,923 10 Nov/nov 2000 US
(10.11.2000)
(43) 25 May/mai 2001 (25.05.2001)
(54) • TRICYCLIC DIHYDROPYRIMIDINE
POTASSIUM CHANNEL OPENERS
• OUVREURS DE CANAUX POTAS-
SIQUES DU TYPE DIHYDROPYRIMI-
DINE TRICYCLIQUE
(71) ABBOTT LABORATORIES [US/US];
Dept. 377/AP6D-2, 100 Abbott Park Road,
Abbott Park, IL 60064-6050 (US).
(72) HOLLADAY, Mark, W.; 6480 East Placita
Acambay, Tucson, AZ 85750 (US). CAR-
ROLL, William, A.; 2514 Prairie, Apt. 3B,
Evanston, IL 60201 (US). DRIZIN, Irene;
16764 West Cherrywood Lane, Wadsworth,
IL 60083 (US). YI, Lin; 1738 Hillside Court,
Gurnee, IL 60031 (US). ZHANG, Henry, Q.;
107 Suffolk Lane, Grayslake, IL 60030 (US).
(74) WARD, Michael, J. et al. / etc.; Dept.
377/AP6D-2, 100 Abbott Park Road, Abbott
Park, IL 60064-6050 (US).
(81) CA JP MX.
(84) EP (AT BE CH CY DE DK ES FI FR GB GR
IE IT LU MC NL PT SE TR).
(51) 7 C07D 491/107, A61K 31/445, A61P 25/00
(11) WO 01/36423
(21) PCT/EP00/11351
(13) A1
(22) 13 Nov/nov 2000 (13.11.2000)
(25) en (26) en
(30) 99309137.0 17 Nov/nov 1999
(17.11.1999)
EP
(43) 25 May/mai 2001 (25.05.2001)
(54) • SPIRO(2H-1-BENZOPYRAN-2,4’-
PIPERIDINE) DERIVATES AS
GLYCINE TRANSPORT INHIBITORS
• DERIVES DE SPIRO(2H-1-BENZO-
PYRAN-2,4’-PIPERIDINE) EN TANT
QU’INHIBITEURS
DE GLYCINE
DE TRANSPORT
(71) AKZO NOBEL N.V. [NL/NL]; Velperweg
76, NL-6824 BM Arnhem (NL).
(for all designated States except / pour tous
les États désignés sauf US)
(72, 75) GIBSON, Samuel, George [GB/GB];
19 Ross Crescent, Motherwell, Lanarkshire
ML1 3AU (GB). MILLER, David, John