International Summer School PROGRAM - Laboratoire d'Infochimie ...

Calixarenes: from molecular receptor to supramolecular systems
I.S.Antipin a,b , S.E. Soloveva a , I.I.Stoikov b , A.I.Konovalov a,b
a A.E.Arbuzov Institute of Organic & Physical Chemistry, 420088, Kazan, Russia,
Arbuzov str., 8. , b Kazan (Volga region) Federal University, 420008, Kazan, Russia,
Kremlevskaya str. 18, E-mail: iantipin@ksu.ru
Now one of the most perspective ways of the nanomaterials design is the "bottom-up"
technology in which the higher organized nanosystems are spontaneously formed due to
supramolecular self-organization and self-assembly from individual atoms and
molecules. A key element of supramolecular chemistry is the principle of the molecular
recognition. From this point of view, one of the actual problems of supramolecular
chemistry is the molecular design and synthesis of preorganized receptor and
amphiphilic molecules which are capable on the principles of molecular recognition and
multipoint interactions to form host-guest complexes as well as self-organized
supramolecular essembles and devices.
Nanotechnological approach "bottom-up" can be effectively implemented on the basis
of meta-cyclophanes: calix[4]arene 1, thiacalix[4]arene 2.
(1) (2) X= O, S, NH
Stereo and chemoselective functionalization of calix[4]arene platforms allows to change
significantly hydrophilic-lipophilic properties of macrocycles and to raise efficiency and
selectivity of the interaction with substrates. The regularities of aggregation and
complexation of calixarenes with substrates of different nature: non-electrolytes,
cations, anions will be discussed. Particular attention will be paid to the application of
calixarene derivatives for the construction of various supramolecular and nanosystems,
devices and "smart" materials: nanoparticles, metal-coordinated networks, Langmuir-
Blodgett nanolayers etc.
The support from RFBR (N 10-03-00728) is gratefully acknowledged.