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Lithium-controlled hierarchical assembly of Ti(IV)-Helicates
Elisabeth Isaak,
Markus Albrecht
Institut für Organische Chemie, RWTH Aachen, Landoltweg 1, 52074 Aachen,
Germany
e-mail: Elisabeth.Isaak@rwth-aachen.de
Dinuclear triple-stranded titanium(IV) complexes are formed in hierarchical, lithiumtemplated
assembly from catecholate ligands and TiO(acac)2.
An equilibrium between
monomeric and dimeric units. For the formation of the dimer, two mononuclear
complexes are connected by non-covalent spacers.
The introduction of chiral information leads to diastereomers. In this study we changed
the position of chiral center and used the ligands from nature's chiral pool building
blocks for favoring one diastereomer.
The properties of the complexes are studied by NMR, ESI FT-ICR MS and CD
spectroscopy methods as well as X-ray diffraction.
References:
[1] M. Albrecht, S. Mirtschin, M. de Groot, I. Janser, J. Runsink,G. Raabe, M. Kogej,
C. A. Schalley and R. Fröhlich, J. Am. Chem. Soc. 2005, 127, 10371.
[2] M. Albrecht, E. Isaak, M. Baumert, V. Gossen, G. Raabe and R. Fröhlich, Angew.
Chem. 2011, 123, 2903; Angew. Chem. Int. Ed., 2011, 50, 2850.