International Summer School PROGRAM - Laboratoire d'Infochimie ...

SYNTHETIC TETRAAMIDES ANION RECEPTORS WITH AZULENE MOIETIES
Dawid Lichosyt, a,b Paweł Dydio b , Janusz Jurczak a,b
a) Institute of Organic Chemistry PAS, Kasprzaka 44/52, 01-224 Warsaw
b)
The Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw
dlichosyt@gmail.com
Anions play crucial role in many fields of chemistry, therefore research on anion
receptors is very important area of supramolecular chemistry.[1] Hydrogen bonds are
the most common among interactions which can be used in anion binding process. Their
accessibility and directionality enables assembly of binding sites adjusted for specific
anionic species.[2,3] In this communication we would like to present our studies on new
ligand 1 with four donors of hydrogen bonds in macrocyclic structure. In this compound
we use azulene moiety, which potentially offers optical anion sensor properties. Our
research show strong affinity 1 towards anions in DMSO + 5% H2O mixture.
To determine how important macrocyclic effect is we synthesized receptor 2.
Furthermore, we obtained diffraction grade crystals of receptor 1 and its complexes with
anions. We will discuss results of their structural analysis.
[1] Sessler J. L.; Gale P. A.; Cho W. S. Anion Receptor Chemistry, The Royal Society of Chemistry,
Cambridge, 2006.
[2] Dydio P.; Lichosyt D.; Jurczak J. Chem. Soc. Rev., 2011,40, 2971-2985
[3] Gale, P. A., Chem. Soc. Rev., 2010, 39, 3746-3771