International Summer School PROGRAM - Laboratoire d'Infochimie ...
International Summer School PROGRAM - Laboratoire d'Infochimie ...
International Summer School PROGRAM - Laboratoire d'Infochimie ...
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The sensing of interfacial interactions of Tb-doped silica nanoparticles<br />
with various substrates through the "on-off-on" switching of Tb-<br />
centered luminescence. Mechanisms and applications.<br />
V. Burilov a,b , A. Mustafina b , V. Skripacheva b , S. Fedorenko b , O. Bochkova b , R.<br />
Zairov b , I. Antipin a,b , A. Konovalov a,b<br />
.<br />
a - Kazan Federal University, A.Butlerov Institute of Chemistry, Kremlyovskaya St.,<br />
18, Kazan 420008; b - A.E. Arbuzov Institute of Organic and Physical Chemistry,<br />
Arbuzov Street, 8, 420088 Kazan, Russia.<br />
Silica nanoparticles have gained much attention during recent decades due to<br />
their wide use in medicine and bioanalysis. Lanthanide complexes have gained a great<br />
deal of attention owing to their unique spectroscopic characteristics, including long<br />
fluorescence lifetime, large Stokes shift, and sharp line-like emission bands. Therefore<br />
lanthanide complexes are applied as dopants into silica nanoparticles. Due to good<br />
signal-to-noise ratio such nanoparticles are efficient biomarkers, while their application<br />
in biosensing is more sparsely. The present report introduces luminescent core-shell<br />
nanoparticles as the nanosized sensors, which recognize inorganic and organic<br />
substrates through the “on-off” and “off-on” switching of the emission. Various<br />
synthetic procedures have been used to modify the morphology of the core-shell<br />
nanoparticles. The comparison of photophysical properties of nanoparticles with various<br />
morphology reveals the effect of coating on the luminescence. The “on-off” switching<br />
results from the interfacial interactions of the Tb(Eu)-doped nanoparticles with so called<br />
quenching molecules and ions, such as dyes and transition metal ions. The “off-on”<br />
switching can be achieved through the competitive interfacial binding of the quenching<br />
versus nonquenching molecules. Both steady state and time resolved quenching<br />
measurements have been analyzed to distinguish the contributions of static and dynamic<br />
mechanisms in the quenching of the luminescent core through the interfacial<br />
interactions of core-shell nanoparticles with quenching molecules. Though the dynamic<br />
quenching through the energy transfer is the key mechanism, the static quenching<br />
through the readsorption and light scattering should be also taken into account.
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