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Presentation Outline ICHP Annual Meeting September 13-15

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A patient has a CrCl of 25 mL/min. Which dose of<br />

dabigatran should be prescribed for this patient?<br />

– A: <strong>15</strong>0 mg PO daily<br />

– B: 75 mg PO BID<br />

– C: <strong>15</strong>0 mg PO BID<br />

– D: Dabigatran is<br />

contraindicated in<br />

this patient<br />

References<br />

A: <strong>15</strong>0 mg PO daily<br />

0% 0% 0% 0%<br />

B: 75 mg PO BID<br />

C: <strong>15</strong>0 mg PO BID<br />

D: Dabigatran is contrai...<br />

• 1. MayoClinic. Atrial Fibrillation. Available at: http://www.mayoclinic.com/health/atrial‐fibrillation/DS00291 Accessed<br />

November 27, 2011.<br />

• 2. Boehringer Ingelheim Pharmaceuticals, Inc. How AFib can cause a stroke. Available at: https://www.afibstroke.com/blood‐<br />

clot‐causes‐<br />

stroke.jsp?sc=PRDACQWEBGGLDDG1203103&utm_source=google&utm_medium=cpc&utm_term=afib&utm_campaign=Afi<br />

b_Unbranded Accessed April 7, 2012.<br />

• 3. Warfarin [Prescribing Information]. Haifa Bay, Israel: Taro Pharmaceutical Industries Ltd; 2009.<br />

• 4. Pradaxa® [Prescribing Information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2012.<br />

• 5. Connolly y SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran g versus warfarin in ppatients with atrial fibrillation. N Engl g J Med 2009;<br />

361:1<strong>13</strong>9‐51.<br />

• 6. Boehringer Ingelheim Pharmaceuticals, Inc. Pradaxa. Available at: http://www.pradaxa.com/ Accessed April 7, 2012.<br />

Residency Project Pearls<br />

From Dabigatran to Warfarin: A<br />

Change g in Progress g<br />

Ashley Jacobs, Pharm.D.<br />

Clinical‐Staff Pharmacist<br />

Lutheran Health Network<br />

Fort Wayne, IN<br />

<strong>September</strong> 2012<br />

Disclosure: The speaker has no actual or potential conflict of interest in relation to this presentation.<br />

Which organ system is commonly associated<br />

with dabigatran side effects?<br />

– A: Respiratory system<br />

– B: Endocrine system<br />

– C: Excretory system<br />

– D: Digestive system<br />

A: Respiratory system<br />

0% 0% 0% 0%<br />

B: Endocrine system<br />

C: Excretory system<br />

http://www.vietvaluetravel.com/blog/2012/02/21/most‐asked‐questions‐about‐vietnam/<br />

D: Digestive system<br />

8/29/2012<br />

4

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