Presentation Outline ICHP Annual Meeting September 13-15

Which patient might be a candidate for
aspirin for prevention of recurrent VTE?
A. Unprovoked VTE, 6
month of VKA therapy,
low bleed risk
B. Unprovoked VTE, 3
months of VKA therapy,
low bleed risk
C. Provoked VTE, 6 months
of VKA therapy, low
bleed risk
D. Unprovoked VTE, 6
months of VKA therapy,
GI bleed 15 months ago
Media‐Worthy Trial Assessment #2:
AZITHROMYCIN AND THE RISK OF
CARDIOVASCULAR DEATH
N Engl J Med. 2012;366(20):1881-1889.
Azithromycin
• Background
– Macrolide antibiotics have proarrhythmic
potential
• QT prolongation
• Torsades de pointes
• Sudden cardiac death
– Up until recently, findings did not apply to
azithromycin
Clin Infect Dis. 2006;43(12):1603-1611.
8/30/2012
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