Presentation Outline ICHP Annual Meeting September 13-15

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Mean Survival by Etiology CHD, congenital heart disease; CTD, connective tissue disease; IPAH, idiopathic pulmonary arterial hypertension; Portopulm, portopulmonary hypertension McLaughlin VV, et al. J Am Coll Cardiol. 2009;53:<strong>15</strong>73-1619. Pathophysiology Normal PAH McLaughlin VV, et al. J Am Coll Cardiol. 2009;53:<strong>15</strong>73-1619. Pathophysiology • Endothelin-1 • Nitric oxide • Prostacyclin Serotonin • Serotonin • Vasoactive intestinal peptide (VIP) • Inflammation 8
PAH Therapy Targets Schulze-Neick I, Beghetti M. Eur Respir Rev. 2010;19:331–9. Serotonin • Effects – Vasoconstriction – Smooth muscle cell hyperplasia and hypertrophy • Impaired platelet serotonin storage in PAH – Dexfenfluramine • No PAH-SSRI association McLaughlin VV, et al. Curr Probl Cardiol. 2011;36:461-517. Marcos E, et al. Am J Respir Crit Care Med. 2003;168:487-93. VIP • Effects – Vasodilatation – Inhibition of vascular smooth muscle cell proliferation • Low levels in PAH population McLaughlin VV, et al. Curr Probl Cardiol. 2011;36:461-517. 9
Page 1 and 2: ACTIVITY DESCRIPTION Target Audienc
Page 3 and 4: Current Challenges • Expansion of
Page 5 and 6: Examples of Medication Consideratio
Page 7: Etiology (Dana Point, 2008) 1’. P
Page 11 and 12: Chronic Adjuvant Therapies in PAH D
Page 13 and 14: Cummulative suurvival Survival in I
Page 15 and 16: ACCF/AHA Consensus PAH Treatment Al
Page 17 and 18: Study Name Drug SUPER-1 Oral silden
Page 19 and 20: IV Epoprostenol in PAH Due to Scler
Page 21 and 22: 70 60 50 40 30 20 10 Inhaled Ilopro
Page 23 and 24: Conclusions • PAH therapy improve
Page 25 and 26: ESC/ERS Guidelines Galie N, et al.
Page 27 and 28: FUTURE DIRECTIONS WHICH MAY IMPACT
Page 29 and 30: Rationale for “Front-Loaded” Ap
Page 31 and 32: Addressing gthe Challenges g in PAH
Page 33 and 34: Considerations • Central vs. peri
Page 35 and 36: Pulmonary Hypertension • Approxim
Page 37 and 38: Example Cassette Calculations • V
Page 39 and 40: Assessment Question 1 Which of the
Page 41 and 42: Illinois Council of Health‐System
Page 43 and 44: Patient Activity ‐ 1 Patients in
Page 45 and 46: Hospitalists National Trends • Ja
Page 47 and 48: Pharmacy Landscape • PGY‐2: So
Page 49 and 50: Primary Care Physicians by Field, F
Page 51 and 52: Health Systems Pharmacy and TATAI
Page 53 and 54: Readings The 21 Irrefutable Laws of
Page 55 and 56: What is a “Practice Model”? •
Page 57 and 58: Completing the Self Assessment •
Page 59 and 60:
Residency trained (B23p) Illinois N
Page 61 and 62:
Solving the PPMI Puzzle ‐ Here Ar
Page 63 and 64:
Overview of Value Based Purchasing
Page 65 and 66:
Implementation of Medication‐ rel
Page 67 and 68:
Question #1 Within which programs a
Page 69 and 70:
Solving the PPMI Puzzle‐ Here are
Page 71 and 72:
Discharge Education/Med Rec • New
Page 73 and 74:
Media‐Worthy Trials? Making Sense
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Prevention of Recurrent VTE • Unp
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VTE recurrence during study period
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Which patient might be a candidate
Page 81 and 82:
Azithromycin and CV Death • Endpo
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Azithromycin and CV Death Azithromy
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Hormonal Contraception and VTE •
Page 87 and 88:
• Age • Calendar year • Educa
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ARR=2.20, 2.28 for stroke, MI when
Page 91 and 92:
Which of the following combinations
Page 93 and 94:
3 Months of Treatment for Latent TB
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3 Months of Treatment for Latent TB
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T/F: Rifapentine in combination wit
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2. Which of the following statement
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Fitting the Counseling Piece into M
Page 103 and 104:
Current Evidence: Implementing Bund
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Teach Back Process • Step 1 Expla
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Questions for Consideration and Dis
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Why do we care about ADE? • Adver
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True or False • Medication errors
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Check Point Which of the following
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Proactive Screening Process Patient
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MTI Pilot at NAH PharmD Students tr
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ASHP PPMI Case Study Adding Value:
Page 121 and 122:
Interdisciplinary Teamwork: How Phy
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Highly Effective Healthcare • Wha
Page 125 and 126:
Inter‐Professional Teams ‐ Chan
Page 127 and 128:
Meeting the PPMI Goals for Technolo
Page 129 and 130:
Drug‐Bug Mismatch Example Con’t
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Drug‐Bug Mismatch Build Rules •
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Page 135 and 136:
Patient Scanning Compliance Sample
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Page 139 and 140:
Global Immunizations 3 • Jan 2012
Page 141 and 142:
Mobile Devices: Beyond Angry Birds
Page 143 and 144:
Google Play • Google Play - Inter
Page 145 and 146:
Other Useful Productivity Apps •
Page 147 and 148:
Mobile Devices: Beyond Angry Birds
Page 149 and 150:
Net Activations by Industry Source:
Page 151 and 152:
News Readers/Aggregators Features S
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Contact Information • E‐mail: -
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Early‐Onset Sepsis • Sign and s
Page 157 and 158:
• BR is on day 2 of cefotaxime wi
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Immunizations: The Superheroes to P
Page 161 and 162:
Current ACIP Recommendations Influe
Page 163 and 164:
Herpes Zoster Vaccine Recommendatio
Page 165 and 166:
Assessment Questions 1. What are th
Page 167 and 168:
HIV Linkage and Retention in Care T
Page 169 and 170:
DHHS Guidelines, March 2012: When t
Page 171 and 172:
Protease Inhibitors • Require “
Page 173 and 174:
Mean Change (mg/ /dL) STARTMRK: Lip
Page 175 and 176:
RAL Drug Interactions • Does not
Page 177 and 178:
Instructions for Credit In order to
Page 179 and 180:
Staging Stage Criteria (Durie‐Sal
Page 181 and 182:
Salvage Therapy Partial List Regime
Page 183 and 184:
Bortezomib-Thalidomide-Dexamethason
Page 185 and 186:
Case 2 ST is a 76 y/o African Ameri
Page 187 and 188:
Thalidomide and Lenalidomide • Ad
Page 189 and 190:
Fixed Low-Dose Warfarin Study Thera
Page 191 and 192:
New Drugs 2012 Anna Nowobilski‐Va
Page 193 and 194:
Pulmonology » Cystic Fibrosis •
Page 195 and 196:
Oncology » MTX Toxicity • MTX 1o
Page 197 and 198:
NEW DRUGS AND BIOLOGICALS 2012 RESO
Page 199 and 200:
Disease State Reviews for Pharmacy
Page 201 and 202:
Chronic Obstructive Pulmonary Disea
Page 203 and 204:
Page 205 and 206:
Green Zone • Patient is not havin
Page 207 and 208:
Page 209 and 210:
• A hormone produced by the pancr
Page 211 and 212:
Unraveling Unraveling The The Puzzl
Page 213 and 214:
The Reward Center In time, serious
Page 215 and 216:
So what makes addicted pharmacists
Page 217 and 218:
How to find a treatment center Onli
Page 219 and 220:
Internet Drug Abuse Study conducted
Page 221 and 222:
NIAAA = best resource for alcohol d
Page 223 and 224:
Impact of Postoperative Pain • Pi
Page 225 and 226:
Safety Profile • Amar et al confi
Page 227 and 228:
References 1. Rømsing J, Møiniche
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Society of Regional Anesthesia Meet
Page 231 and 232:
A New Approach IV Acetaminophen •
Page 233 and 234:
References • Schechter, Leslie N.
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Bupivacaine liposome injectable sus
Page 237 and 238:
Error Potential • Inadvertent IV
Page 239 and 240:
Decolonization Methods • Anti-sep
Page 241 and 242:
Evidence: Inpatient ICU MRSA Coloni
Page 243 and 244:
Residency Project Pearls Adherence
Page 245 and 246:
650 subjects id identified tifi d R
Page 247 and 248:
Overtreatment versus Appropriate Tr
Page 249 and 250:
Adherence to and Outcomes Associate
Page 251 and 252:
Background • Lack of comprehensiv
Page 253 and 254:
Results Results‐User User Audits
Page 255 and 256:
Special thanks to: • Carol Heunis
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Antibiotic Prophylaxis American Hea
Page 259 and 260:
Study Limitations • Dependent on
Page 261 and 262:
Study Background • Observation of
Page 263 and 264:
A patient has a CrCl of 25 mL/min.
Page 265 and 266:
• Cysteine hydrochloride: antioxi
Page 267 and 268:
Sample Preparation • Intravenous
Page 269 and 270:
Questions? Residency Project Pearls
Page 271 and 272:
The Interview: Your Preparation •
Page 273 and 274:
PGY1 Residency Options Carol Heunis
Page 275 and 276:
RESIDENCY PROGRAM BASICS • Progra
Page 277 and 278:
CV: The key to a top curriculum vit
Page 279 and 280:
Tips for a Top Notch CV • Focus o
Page 281 and 282:
What is PhORCAS? • PhORCAS is the
Page 283 and 284:
Piecing together the new CHEST guid
Page 285 and 286:
Initiating therapy CHEST 2012 2.1.8
Page 287 and 288:
What is “Consistently Stable?”
Page 289 and 290:
Puzzle # 2A: patient has just compl
Page 291 and 292:
What would you do for JJ? • A. Ho
Page 293 and 294:
Considerations for SB • Bleeding
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Presentation Outline ICHP Annual Meeting September 13-15

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