Presentation Outline ICHP Annual Meeting September 13-15

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Cumulative Incidence of Death (no./1 million courses) Among Patients Taking a 5‐Day Course of Azithromycin, Amoxicillin, or No Antibiotic No Antibiotic Amoxicillin Azithromycin HR, 2.88 95% CI, 1.79-4.63 P
Azithromycin and CV Death Azithromycin Vs. Fluoroquinolones • Azithromycin increased risk for CV death compared to ciprofloxacin • HR HR, 3.49; 349 95% CI CI, <strong>13</strong>2t 1.32 to 926 9.26; P001 P=0.01 • Azithromycin did not increase risk for CV death compared to levofloxacin • HR, 1.27; 95% CI, 0.66 to 2.47; P=0.48 N Engl J Med. 2012;366(20):1881-1889. Azithromycin and CV Death Overall Conclusion Patients should not stop taking • Azithromycin until resulted discussing in with small healthcare but significant professional. Prescribers should increase in risk for CV death be aware of the potential for QT – Increase greatest prolongation for those and found arrhythmias to be at highest CV risk with azithromycin. • 47 additional CV deaths per 1 million courses of azithromycin therapy when compared to amoxicillin • Also increased risk for overall death, but not non‐CV death N Engl J Med. 2012;366(20):1881-1889. Azithromycin and CV Death Strengths • Large cohort observed over several years • 2 controls for confounders • Validity of study assumptions tested, with similar results N Engl J Med. 2012;366(20):1881-1889. Limitations • Observational, cannot observe cause and effect • Data from only 1 geographic location • Difficult to extrapolate to men, race other than white • Accuracy of database/coding 8/30/2012 11
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ACTIVITY DESCRIPTION Target Audienc
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Current Challenges • Expansion of
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Examples of Medication Consideratio
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Etiology (Dana Point, 2008) 1’. P
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PAH Therapy Targets Schulze-Neick I
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Chronic Adjuvant Therapies in PAH D
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Cummulative suurvival Survival in I
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ACCF/AHA Consensus PAH Treatment Al
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Study Name Drug SUPER-1 Oral silden
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IV Epoprostenol in PAH Due to Scler
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70 60 50 40 30 20 10 Inhaled Ilopro
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Conclusions • PAH therapy improve
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ESC/ERS Guidelines Galie N, et al.
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FUTURE DIRECTIONS WHICH MAY IMPACT
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Rationale for “Front-Loaded” Ap
Page 31 and 32: Addressing gthe Challenges g in PAH
Page 33 and 34: Considerations • Central vs. peri
Page 35 and 36: Pulmonary Hypertension • Approxim
Page 37 and 38: Example Cassette Calculations • V
Page 39 and 40: Assessment Question 1 Which of the
Page 41 and 42: Illinois Council of Health‐System
Page 43 and 44: Patient Activity ‐ 1 Patients in
Page 45 and 46: Hospitalists National Trends • Ja
Page 47 and 48: Pharmacy Landscape • PGY‐2: So
Page 49 and 50: Primary Care Physicians by Field, F
Page 51 and 52: Health Systems Pharmacy and TATAI
Page 53 and 54: Readings The 21 Irrefutable Laws of
Page 55 and 56: What is a “Practice Model”? •
Page 57 and 58: Completing the Self Assessment •
Page 59 and 60: Residency trained (B23p) Illinois N
Page 61 and 62: Solving the PPMI Puzzle ‐ Here Ar
Page 63 and 64: Overview of Value Based Purchasing
Page 65 and 66: Implementation of Medication‐ rel
Page 67 and 68: Question #1 Within which programs a
Page 69 and 70: Solving the PPMI Puzzle‐ Here are
Page 71 and 72: Discharge Education/Med Rec • New
Page 73 and 74: Media‐Worthy Trials? Making Sense
Page 75 and 76: Prevention of Recurrent VTE • Unp
Page 77 and 78: VTE recurrence during study period
Page 79 and 80: Which patient might be a candidate
Page 81: Azithromycin and CV Death • Endpo
Page 85 and 86: Hormonal Contraception and VTE •
Page 87 and 88: • Age • Calendar year • Educa
Page 89 and 90: ARR=2.20, 2.28 for stroke, MI when
Page 91 and 92: Which of the following combinations
Page 93 and 94: 3 Months of Treatment for Latent TB
Page 95 and 96: 3 Months of Treatment for Latent TB
Page 97 and 98: T/F: Rifapentine in combination wit
Page 99 and 100: 2. Which of the following statement
Page 101 and 102: Fitting the Counseling Piece into M
Page 103 and 104: Current Evidence: Implementing Bund
Page 105 and 106: Teach Back Process • Step 1 Expla
Page 107 and 108: Questions for Consideration and Dis
Page 109 and 110: Why do we care about ADE? • Adver
Page 111 and 112: True or False • Medication errors
Page 113 and 114: Check Point Which of the following
Page 115 and 116: Proactive Screening Process Patient
Page 117 and 118: MTI Pilot at NAH PharmD Students tr
Page 119 and 120: ASHP PPMI Case Study Adding Value:
Page 121 and 122: Interdisciplinary Teamwork: How Phy
Page 123 and 124: Highly Effective Healthcare • Wha
Page 125 and 126: Inter‐Professional Teams ‐ Chan
Page 127 and 128: Meeting the PPMI Goals for Technolo
Page 129 and 130: Drug‐Bug Mismatch Example Con’t
Page 131 and 132: Drug‐Bug Mismatch Build Rules •
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Meeting the PPMI Goals for Technolo
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Patient Scanning Compliance Sample
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Meeting the PPMI Goals for Technolo
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Global Immunizations 3 • Jan 2012
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Mobile Devices: Beyond Angry Birds
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Google Play • Google Play - Inter
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Other Useful Productivity Apps •
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Mobile Devices: Beyond Angry Birds
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Net Activations by Industry Source:
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News Readers/Aggregators Features S
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Contact Information • E‐mail: -
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Early‐Onset Sepsis • Sign and s
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• BR is on day 2 of cefotaxime wi
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Immunizations: The Superheroes to P
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Current ACIP Recommendations Influe
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Herpes Zoster Vaccine Recommendatio
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Assessment Questions 1. What are th
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HIV Linkage and Retention in Care T
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DHHS Guidelines, March 2012: When t
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Protease Inhibitors • Require “
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Mean Change (mg/ /dL) STARTMRK: Lip
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RAL Drug Interactions • Does not
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Instructions for Credit In order to
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Staging Stage Criteria (Durie‐Sal
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Salvage Therapy Partial List Regime
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Bortezomib-Thalidomide-Dexamethason
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Case 2 ST is a 76 y/o African Ameri
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Thalidomide and Lenalidomide • Ad
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Fixed Low-Dose Warfarin Study Thera
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New Drugs 2012 Anna Nowobilski‐Va
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Pulmonology » Cystic Fibrosis •
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Oncology » MTX Toxicity • MTX 1o
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NEW DRUGS AND BIOLOGICALS 2012 RESO
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Disease State Reviews for Pharmacy
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Chronic Obstructive Pulmonary Disea
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Green Zone • Patient is not havin
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• A hormone produced by the pancr
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Unraveling Unraveling The The Puzzl
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The Reward Center In time, serious
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So what makes addicted pharmacists
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How to find a treatment center Onli
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Internet Drug Abuse Study conducted
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NIAAA = best resource for alcohol d
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Impact of Postoperative Pain • Pi
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Safety Profile • Amar et al confi
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References 1. Rømsing J, Møiniche
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Society of Regional Anesthesia Meet
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A New Approach IV Acetaminophen •
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References • Schechter, Leslie N.
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Bupivacaine liposome injectable sus
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Error Potential • Inadvertent IV
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Decolonization Methods • Anti-sep
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Evidence: Inpatient ICU MRSA Coloni
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Residency Project Pearls Adherence
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650 subjects id identified tifi d R
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Overtreatment versus Appropriate Tr
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Adherence to and Outcomes Associate
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Background • Lack of comprehensiv
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Results Results‐User User Audits
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Special thanks to: • Carol Heunis
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Antibiotic Prophylaxis American Hea
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Study Limitations • Dependent on
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Study Background • Observation of
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A patient has a CrCl of 25 mL/min.
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• Cysteine hydrochloride: antioxi
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Sample Preparation • Intravenous
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Questions? Residency Project Pearls
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The Interview: Your Preparation •
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PGY1 Residency Options Carol Heunis
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RESIDENCY PROGRAM BASICS • Progra
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CV: The key to a top curriculum vit
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Tips for a Top Notch CV • Focus o
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What is PhORCAS? • PhORCAS is the
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Piecing together the new CHEST guid
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Initiating therapy CHEST 2012 2.1.8
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What is “Consistently Stable?”
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Puzzle # 2A: patient has just compl
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What would you do for JJ? • A. Ho
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Considerations for SB • Bleeding
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Presentation Outline ICHP Annual Meeting September 13-15

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