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7° Congresso Nazionale

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RESULTS<br />

All patients are alive; for 57 nephrolithotripsy procedures<br />

stone-free rate was 98.3%; in 1 pt (1,7%) the procedure<br />

was unsuccessful (impossibility to perform<br />

nephrostomic access); in 3 pts (5,2%) occured bleeding<br />

with bladder plugging at drainage remove (3rd postoperative<br />

day) that needed stenting (mono J catheter for<br />

some days) and in two patients (2/3 pts) blood transfusion<br />

(3 units of heterologous blood in 1 pt and 1 unit of<br />

autologous blood in 1 pt); in 5 patients (8,7%) the postoperative<br />

anaemia without evidence of significant bleeding<br />

needed blood transfusion (2 units of autologous<br />

blood each in 4 patients and 1 unit of heterologous<br />

blood in 1 patient); totally, 7/63 pts were transfused<br />

(11%); in 1 patient in 7th postoperative day<br />

hydronephrosis without evidence of residual stones, that<br />

needed stenting; for residual procedures (6 patients)<br />

there were no complications; the mean extimated blood<br />

loss was 0,65 + 1,05 g/dL HB (range 0,1- 3,9 g/dL HB);<br />

the mean hospital stay was 4,2 + 2,8 days (range 2- 14<br />

days).<br />

DISCUSSION<br />

The recent introduction on the market of miniaturized<br />

instruments has given strong evidence to the possibilities<br />

of being less invasive in the percutaneous procedures.<br />

This was made possible by the small diameter probes<br />

suitable to be used with L.A.SE.R., which proves very<br />

useful in lithotripsy. Besides the presence of flexible<br />

fibroscopes is highly suitable for the exploration of the<br />

renal cavities.<br />

All this has led to the construction of operative nephroscopes,<br />

aimed to obtaining the same results with the least<br />

possible parenchymal loss.<br />

Until the last year the few experiences of “minipercutaneous<br />

procedures” had to be effected with a technology<br />

unfit for this purpose, but adapted to the specific case, as<br />

in our experience, with obvious limitations in use and<br />

indication.<br />

In literature too very little has been said about mini percutaneous<br />

but only about single or rare experiences,<br />

often in the pediatric field, without the necessary directions<br />

for the standardization of the technical and instrumental<br />

characteristics required by any procedure for an<br />

objective analysis of the result.<br />

If all the Authors mentioned have agreed on the need of<br />

being as least invasive as possible towards the kidney by<br />

effecting nephrostomic approach of small diameter, there<br />

is always the problem of using different instruments, so<br />

in the pediatric experience.<br />

Even if Traxers experimental reports do not show, after 6<br />

weeks, different functional results in terms of parenchimal<br />

damage, utilizing different sized nephrostomy tract<br />

(11 or 30 Fr)(1).<br />

Jackman et al (2). Helal et al (3) described initially the<br />

technique in children with the use of 11 Fr to 15 Fr peelaway<br />

and subsequently the use of a 13 Fr ureteroscopy<br />

sheath for working access. Feng et.(4) al in a prospective<br />

randomized trial to assess the efficacy and morbidity<br />

through standard PCN involved tract dilation to 30 Fr<br />

for passage of a 34 Fr working sheath and their 2 mini-<br />

<strong>7°</strong> <strong>Congresso</strong> <strong>Nazionale</strong> Associazione Italiana di Endourologia<br />

PCN involved tract dilation to 22 Fr for passage of a 26<br />

Fr sheath with tubeless procedure, no overall advantage<br />

was found for the mini-PCN versus the standard technique,<br />

imputing however the disadvantages of the microprocedures<br />

to the poorer visualization and optics and<br />

difficulty with the use of the nephroscopic graspers.<br />

Chan et al.(5) describes the use mini-PCN by means of<br />

13 Fr ureteroscopy and stresses how the procedure<br />

reduces morbidity compared with the standard procedure<br />

in terms of efficiency and effectiveness for stone<br />

removal.<br />

In the abstract “role of Miniperc in the management of<br />

urolithiasis”, Bhargava et al. (6) evaluate the effectiveness<br />

of the procedure with 14 Fr (19 cm Length) access<br />

ureteric sheath and the use of the ureteroscopy of 8 Fr<br />

and pneumatic lithotripsy in 30 patients. They conclude<br />

that ”Miniperc” is a safe and very useful procedure.<br />

Also Monga et al.(7) describes the miniaturization of percutaneous<br />

nephrolithotomy, a natural evolution of the<br />

gold standard by using of 20 Fr compared with the traditional<br />

30 Fr sheath. The Author points out that the<br />

reduction of the approach allows less bleeding and postoperative<br />

pain in 16 patients.<br />

Desai et al. (8) refers to a paediatric surgery experience<br />

with 45 renal Units in 40 cases using the paediatric<br />

nephroscope 14 Fr with a 2,4 mm working channel with<br />

dilatation of the approach from 18,5 to 24 Fr according<br />

to the age of the children. The Authors describes this<br />

procedure as safe ed appropriate option in the modern<br />

management of paediatric urolithiasis.<br />

Also Zattoni (9) in his personal experience (with the new<br />

17 Fr nephroscope in renal stone and nephrostomic<br />

channel of 20 Fr) of 9 cases including 6 children suggests<br />

that paediatric nephroscope should be considered a standard<br />

part of the endourologic equipment.<br />

In our experience, the miniperc procedures allows significant<br />

reduction in blood loss: in a previous study of<br />

our group (10) we have compared three groups of<br />

patients that’s undergoes percutaneous procedures with<br />

various techniques of nephrostomy tract dilation to 34<br />

Fr: 105 total patients, of which 59 progressive dilation<br />

with Amplatz metallic dilators, 36 with One- Shot technique<br />

and 15 with pneumatic dilation: in first group the<br />

extimated blood loss was 2,08 + 1,43 g/dL HB (0,3- 8,7<br />

g/dL), in second group 1,64 + 0,95 g/dL HB (0- 3,9<br />

g/dL), in third group 1,90 + 1,12 g/dL (0,2- 3,7 g/dL); in<br />

our actual series the extimated blood loss was 0,65 +<br />

1,05 g/dL (0,1- 3,9 g/dL); the data are particularly significant<br />

in comparison with first group (p < 0,001), but<br />

remains also significant in comparison with second<br />

group (p < 0,05) and third group (p < 0,02) (Table 3).<br />

In our previous study we have also evaluated mean operating<br />

times, that were respectively 38 minutes with<br />

Alken metallic dilators, and 29 minutes with One-Shot<br />

or pneumatic dilation. In actual series mean operating<br />

times are more of 60 minutes: a demonstration (statistically<br />

significant, but also intuitive) of major expensiveness<br />

in operating time of miniperc procedures in comparison<br />

with standard nephrostomy tract accesses, independently<br />

of dilation technique. The mean hospital stay<br />

in present study was 4,2 + 2,8 days (range 2- 14 days);<br />

in previous study was 5,74 +3,54 days (range 2-20 days)<br />

Archivio Italiano di Urologia e Andrologia 2007, 79, 3, Supplemento 1<br />

45

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