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Asbestos Fibers and Other Elongate Mineral Particles: State of the ...

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to EMPs, with periodic summary reporting <strong>of</strong><br />

findings. Representative EMP exposure data<br />

could help identify worker populations or particular<br />

types <strong>of</strong> EMPs warranting fur<strong>the</strong>r study<br />

(i.e., more in-depth exposure assessment; medical<br />

surveillance; epidemiologic studies <strong>of</strong> particular<br />

types <strong>of</strong> EMPs, processes, job tasks, occupations,<br />

or industries; <strong>and</strong> toxicity studies <strong>of</strong><br />

particular EMPs). Occupational exposure data<br />

should be collected <strong>and</strong> stored in a comprehensive<br />

database. Information similar to that<br />

described by Marchant et al. [2002] should be<br />

incorporated into <strong>the</strong> database to support <strong>the</strong>se<br />

efforts. This could be accomplished in parallel<br />

with efforts to develop an occupational exposure<br />

database for nanotechnology [Miller et al. 2007]<br />

or efforts to develop a national occupational exposure<br />

database [Middendorf et al. 2007].<br />

3.5.2 Collect <strong>and</strong> Analyze Available<br />

Information on Health<br />

Outcomes Associated with<br />

Exposures to <strong>Asbestos</strong> <strong>Fibers</strong><br />

<strong>and</strong> <strong>O<strong>the</strong>r</strong> EMPs<br />

The body <strong>of</strong> knowledge concerning human<br />

health effects from exposure to EMPs consists<br />

primarily <strong>of</strong> findings from epidemiological<br />

studies <strong>of</strong> workers exposed to asbestos fibers.<br />

There is general agreement that workers exposed<br />

to fibers from any asbestiform amphibole<br />

mineral would be at risk <strong>of</strong> serious adverse<br />

health outcomes <strong>of</strong> <strong>the</strong> type caused by<br />

exposure to fibers from <strong>the</strong> six commercially<br />

exploited asbestos minerals. NIOSH commented<br />

on <strong>the</strong> most recently proposed MSHA<br />

rule on asbestos (subsequently promulgated as<br />

a final rule), stating that “NIOSH remains concerned<br />

that <strong>the</strong> regulatory definition <strong>of</strong> asbestos<br />

should include asbestiform mineral fibers<br />

such as winchite <strong>and</strong> richterite, which were<br />

<strong>of</strong> major importance as contaminants in <strong>the</strong><br />

NIOSH CIB 62 • <strong>Asbestos</strong><br />

Libby, MT, vermiculite” [NIOSH 2005]. To ensure<br />

a clear science base that might support a<br />

formal recommendation for control <strong>of</strong> occupational<br />

exposures to all asbestiform amphibole<br />

fibers, it would be reasonable to thoroughly<br />

review, assess, <strong>and</strong> summarize <strong>the</strong> available<br />

information on asbestiform amphiboles such<br />

as winchite, richterite, <strong>and</strong> fluoro-edenite that<br />

have not been commercially exploited.<br />

It will also be important to quantitatively determine<br />

<strong>the</strong> health risks posed by EMPs from<br />

nonasbestiform amphiboles <strong>and</strong> to compare<br />

<strong>the</strong>m to <strong>the</strong> risks posed by fibers from asbestiform<br />

amphiboles. If nonasbestiform amphibole<br />

EMPs are, in fact, associated with some risk, a<br />

quantitative risk assessment would be needed<br />

to underst<strong>and</strong> <strong>the</strong> risks relative to those associated<br />

with exposures to asbestos fibers. If new<br />

epidemiological <strong>and</strong> o<strong>the</strong>r evidence is sufficient<br />

to support such a risk estimate, that could lead<br />

to <strong>the</strong> development <strong>of</strong> risk management policies<br />

for nonasbestiform amphibole EMPs distinct<br />

from risk management policies for asbestos fibers.<br />

Risk management policies that differ for<br />

asbestiform <strong>and</strong> nonasbestiform amphiboles<br />

would motivate <strong>the</strong> development <strong>and</strong> routine<br />

use <strong>of</strong> new analytical methods that differentiate<br />

asbestiform from nonasbestiform particles.<br />

In addition to collecting <strong>and</strong> analyzing information<br />

on health outcomes associated with exposures<br />

to asbestiform EMPs <strong>and</strong> EMPs from<br />

nonasbestiform amphiboles, similar information<br />

related to o<strong>the</strong>r EMPs (e.g., erionite, wollastonite,<br />

attapulgite, <strong>and</strong> fibrous talc) should be collected<br />

for systematic analysis. Additional relevant information<br />

may be gleaned from epidemiological<br />

studies conducted on some SVFs (e.g., glass <strong>and</strong><br />

mineral wool fibers, ceramic fibers).<br />

Surveillance <strong>and</strong> epidemiological studies generally<br />

have been circumscribed by <strong>the</strong> long latency<br />

83

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