Asbestos Fibers and Other Elongate Mineral Particles: State of the ...
Asbestos Fibers and Other Elongate Mineral Particles: State of the ...
Asbestos Fibers and Other Elongate Mineral Particles: State of the ...
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to EMPs, with periodic summary reporting <strong>of</strong><br />
findings. Representative EMP exposure data<br />
could help identify worker populations or particular<br />
types <strong>of</strong> EMPs warranting fur<strong>the</strong>r study<br />
(i.e., more in-depth exposure assessment; medical<br />
surveillance; epidemiologic studies <strong>of</strong> particular<br />
types <strong>of</strong> EMPs, processes, job tasks, occupations,<br />
or industries; <strong>and</strong> toxicity studies <strong>of</strong><br />
particular EMPs). Occupational exposure data<br />
should be collected <strong>and</strong> stored in a comprehensive<br />
database. Information similar to that<br />
described by Marchant et al. [2002] should be<br />
incorporated into <strong>the</strong> database to support <strong>the</strong>se<br />
efforts. This could be accomplished in parallel<br />
with efforts to develop an occupational exposure<br />
database for nanotechnology [Miller et al. 2007]<br />
or efforts to develop a national occupational exposure<br />
database [Middendorf et al. 2007].<br />
3.5.2 Collect <strong>and</strong> Analyze Available<br />
Information on Health<br />
Outcomes Associated with<br />
Exposures to <strong>Asbestos</strong> <strong>Fibers</strong><br />
<strong>and</strong> <strong>O<strong>the</strong>r</strong> EMPs<br />
The body <strong>of</strong> knowledge concerning human<br />
health effects from exposure to EMPs consists<br />
primarily <strong>of</strong> findings from epidemiological<br />
studies <strong>of</strong> workers exposed to asbestos fibers.<br />
There is general agreement that workers exposed<br />
to fibers from any asbestiform amphibole<br />
mineral would be at risk <strong>of</strong> serious adverse<br />
health outcomes <strong>of</strong> <strong>the</strong> type caused by<br />
exposure to fibers from <strong>the</strong> six commercially<br />
exploited asbestos minerals. NIOSH commented<br />
on <strong>the</strong> most recently proposed MSHA<br />
rule on asbestos (subsequently promulgated as<br />
a final rule), stating that “NIOSH remains concerned<br />
that <strong>the</strong> regulatory definition <strong>of</strong> asbestos<br />
should include asbestiform mineral fibers<br />
such as winchite <strong>and</strong> richterite, which were<br />
<strong>of</strong> major importance as contaminants in <strong>the</strong><br />
NIOSH CIB 62 • <strong>Asbestos</strong><br />
Libby, MT, vermiculite” [NIOSH 2005]. To ensure<br />
a clear science base that might support a<br />
formal recommendation for control <strong>of</strong> occupational<br />
exposures to all asbestiform amphibole<br />
fibers, it would be reasonable to thoroughly<br />
review, assess, <strong>and</strong> summarize <strong>the</strong> available<br />
information on asbestiform amphiboles such<br />
as winchite, richterite, <strong>and</strong> fluoro-edenite that<br />
have not been commercially exploited.<br />
It will also be important to quantitatively determine<br />
<strong>the</strong> health risks posed by EMPs from<br />
nonasbestiform amphiboles <strong>and</strong> to compare<br />
<strong>the</strong>m to <strong>the</strong> risks posed by fibers from asbestiform<br />
amphiboles. If nonasbestiform amphibole<br />
EMPs are, in fact, associated with some risk, a<br />
quantitative risk assessment would be needed<br />
to underst<strong>and</strong> <strong>the</strong> risks relative to those associated<br />
with exposures to asbestos fibers. If new<br />
epidemiological <strong>and</strong> o<strong>the</strong>r evidence is sufficient<br />
to support such a risk estimate, that could lead<br />
to <strong>the</strong> development <strong>of</strong> risk management policies<br />
for nonasbestiform amphibole EMPs distinct<br />
from risk management policies for asbestos fibers.<br />
Risk management policies that differ for<br />
asbestiform <strong>and</strong> nonasbestiform amphiboles<br />
would motivate <strong>the</strong> development <strong>and</strong> routine<br />
use <strong>of</strong> new analytical methods that differentiate<br />
asbestiform from nonasbestiform particles.<br />
In addition to collecting <strong>and</strong> analyzing information<br />
on health outcomes associated with exposures<br />
to asbestiform EMPs <strong>and</strong> EMPs from<br />
nonasbestiform amphiboles, similar information<br />
related to o<strong>the</strong>r EMPs (e.g., erionite, wollastonite,<br />
attapulgite, <strong>and</strong> fibrous talc) should be collected<br />
for systematic analysis. Additional relevant information<br />
may be gleaned from epidemiological<br />
studies conducted on some SVFs (e.g., glass <strong>and</strong><br />
mineral wool fibers, ceramic fibers).<br />
Surveillance <strong>and</strong> epidemiological studies generally<br />
have been circumscribed by <strong>the</strong> long latency<br />
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