Asbestos Fibers and Other Elongate Mineral Particles: State of the ...
Asbestos Fibers and Other Elongate Mineral Particles: State of the ...
Asbestos Fibers and Other Elongate Mineral Particles: State of the ...
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mineralogical identification <strong>of</strong> airborne EMPs<br />
<strong>and</strong> (2) technical difficulties in generating test<br />
aerosols <strong>of</strong> size-specific EMPs representative <strong>of</strong><br />
worker exposures so that sampling <strong>and</strong> analytical<br />
methods can be tested <strong>and</strong> validated.<br />
Improvements in exposure assessment methods<br />
are needed to increase <strong>the</strong> accuracy <strong>of</strong> <strong>the</strong><br />
methods used to identify, differentiate, <strong>and</strong> count<br />
EMPs captured in air-sampling filter media. Until<br />
new analytical methods are developed <strong>and</strong><br />
validated, it will be necessary to investigate <strong>the</strong><br />
various proposals that have been made to modify<br />
current analytical methods, such as those discussed<br />
in Section 3.6.2, <strong>and</strong> additional modifications<br />
to <strong>the</strong> current analytical methods.<br />
Manual microscopy methods are labor- intensive<br />
<strong>and</strong> error-prone. Automated analyses would<br />
permit examination <strong>of</strong> larger sample fractions<br />
<strong>and</strong> improve <strong>the</strong> accuracy <strong>of</strong> particle classification.<br />
Developing a practical method that accurately<br />
counts <strong>and</strong> sizes all EMPs could improve<br />
risk assessments <strong>and</strong> exposure assessments done<br />
in support <strong>of</strong> risk management. Automated<br />
methods could reduce operator bias <strong>and</strong> interlaboratory<br />
variability, providing more consistent<br />
results for risk assessments.<br />
Some barriers to improving current analytical<br />
methods have been identified. Increasing <strong>the</strong><br />
optical resolution <strong>of</strong> PCM analysis may help<br />
to increase counts <strong>of</strong> thinner asbestos fibers.<br />
However, any increases in optical microscopy<br />
resolution will not be sufficient to detect all asbestos<br />
fibers. In addition, any improvements in<br />
counting EMPs (e.g., an increase in <strong>the</strong> number<br />
<strong>of</strong> EMPs observed <strong>and</strong> counted) will need to<br />
be evaluated by comparing <strong>the</strong>m with counts<br />
made by <strong>the</strong> current PCM method. The use <strong>of</strong><br />
electron microscopy (EM) would improve <strong>the</strong><br />
capability to detect thin fibers <strong>and</strong> also provide<br />
a means to identify many types <strong>of</strong> minerals.<br />
NIOSH CIB 62 • <strong>Asbestos</strong><br />
However, <strong>the</strong> routine use <strong>of</strong> EM would<br />
• require <strong>the</strong> development <strong>of</strong> st<strong>and</strong>ardized<br />
analytical criteria for <strong>the</strong> identification <strong>of</strong><br />
various EMPs;<br />
• require specialized experience in microscopy<br />
<strong>and</strong> mineral identification;<br />
• increase analytical costs; <strong>and</strong><br />
• potentially increase <strong>the</strong> lag time between<br />
collecting <strong>the</strong> sample <strong>and</strong> obtaining results.<br />
In some workplace situations, such as in construction,<br />
increases in <strong>the</strong> time needed to analyze<br />
samples <strong>and</strong> identify EMPs could potentially<br />
delay <strong>the</strong> implementation <strong>of</strong> appropriate<br />
control measures to reduce exposures.<br />
Several potential sampling <strong>and</strong> analytical improvements<br />
are currently under study. Some<br />
<strong>of</strong> <strong>the</strong> studies are aimed at improving <strong>the</strong> accuracy<br />
<strong>of</strong> current techniques used for monitoring<br />
exposures to asbestos. One such study<br />
is evaluating <strong>the</strong> use <strong>of</strong> thoracic samplers for<br />
<strong>the</strong> collection <strong>of</strong> airborne EPs, <strong>and</strong> ano<strong>the</strong>r<br />
concerns <strong>the</strong> use <strong>of</strong> gridded coverslips for<br />
PCM analyses. The proposed use <strong>of</strong> gridded<br />
coverslips for sample evaluation can aid in <strong>the</strong><br />
counting <strong>of</strong> asbestos <strong>and</strong> o<strong>the</strong>r EMPs <strong>and</strong> can<br />
provide a means for “recounting” fibers at specific<br />
locations on a filter sample. Ano<strong>the</strong>r study<br />
is evaluating <strong>the</strong> proposed ASTM method to<br />
determine whe<strong>the</strong>r interoperator variability <strong>of</strong><br />
differential counting (to distinguish fibers <strong>of</strong><br />
asbestos minerals from o<strong>the</strong>r EMPs) is within<br />
an acceptable range.<br />
Research to develop new methods is warranted.<br />
One such research area could be development<br />
<strong>of</strong> methods that would permit assessment <strong>of</strong><br />
<strong>the</strong> potential biopersistence (e.g., durability) <strong>of</strong><br />
EMPs collected on air sampling filters prior to<br />
<strong>the</strong>ir evaluation by PCM or o<strong>the</strong>r microscopic<br />
methods. If durability is deemed biologically<br />
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