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Asbestos Fibers and Other Elongate Mineral Particles: State of the ...

Asbestos Fibers and Other Elongate Mineral Particles: State of the ...

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Contents<br />

Foreword ............................................................ iii<br />

Executive Summary ................................................... v<br />

List <strong>of</strong> Figures ........................................................ xiv<br />

List <strong>of</strong> Tables ......................................................... xiv<br />

Abbreviations ........................................................ xv<br />

Acknowledgments .......................................................... xvii<br />

1 Introduction ....................................................... 1<br />

2 Overview <strong>of</strong> Current Issues ........................................... 5<br />

2.1 Background .................................................. 5<br />

2.2 <strong>Mineral</strong>s <strong>and</strong> <strong>Mineral</strong> Morphology .............................. 6<br />

2.3 Terminology ................................................. 7<br />

2.3.1 <strong>Mineral</strong>ogical Definitions ............................. 8<br />

2.3.2 <strong>O<strong>the</strong>r</strong> Terms <strong>and</strong> Definitions ........................... 9<br />

2.4 Trends in <strong>Asbestos</strong> Use, Occupational Exposures, <strong>and</strong> Disease ...... 9<br />

2.4.1 Trends in <strong>Asbestos</strong> Use ................................ 9<br />

2.4.2 Trends in Occupational Exposure ....................... 10<br />

2.4.3 Trends in <strong>Asbestos</strong>-related Disease ...................... 12<br />

2.5 Workers’ Home Contamination ................................. 14<br />

2.6 Clinical Issues ................................................ 15<br />

2.7 The NIOSH Recommendation for Occupational Exposure<br />

to <strong>Asbestos</strong> ................................................... 17<br />

2.7.1 The NIOSH REL as Revised in 1990 ..................... 18<br />

2.7.2 Clarification <strong>of</strong> <strong>the</strong> Current NIOSH REL ................. 33<br />

2.8 EMPs <strong>O<strong>the</strong>r</strong> than Cleavage Fragments ........................... 34<br />

2.8.1 Chrysotile ........................................... 34<br />

2.8.2 Asbestiform Amphibole <strong>Mineral</strong>s ....................... 36<br />

2.8.3 <strong>O<strong>the</strong>r</strong> <strong>Mineral</strong>s <strong>of</strong> Potential Concern .................... 38<br />

2.9 Determinants <strong>of</strong> Particle Toxicity <strong>and</strong> Health Effects ............... 39<br />

2.9.1 Deposition .......................................... 39<br />

2.9.2 Clearance <strong>and</strong> Retention .............................. 40<br />

xi

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