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PALATINOSEô - a new innovative carbohydrate
What is PALATINOSEô?
Palatinoseô is a new innovative carbohydrate. While providing the glucose-based energy to the body in
a prolonged, slow and low glycemic way, it is fully available and is toothfriendly. It further supports the
body in burning fat. This ingredient profile enables the development of products for a healthy lifestyle.
More detailed information is given below.
PALATINOSEô (generic name: isomaltulose) was approved for use as a novel food/novel food
ingredient in the EU in 2005 1 . In the U.S. Palatinoseô is GRAS (GRAS notification # 184 accepted by
FDA in March 2006). The food status was confirmed by many other countries worldwide.
PALATINOSEô ñ nutritional/physiological properties
Isomaltuloseís nutritional and physiological properties differ distinctly from those of sugar, as a result of this
-1,6-linkage:
The enzymes in the small intestine split isomaltulose down about 4 to 5 times more slowly than sucrose,
as demonstrated by enzyme kinetic studies. This means that a smaller amount of glucose and fructose
from isomaltulose is absorbed into the blood per time unit, compared to the more rapid rate at which the
monosaccharides from sucrose or cooked starches are absorbed.
Furthermore, this absorption does not only take place in the upper parts of the small intestine (as is the
case for quickly absorbed sugars), but along the entire small intestine. This means that isomaltulose still
supplies glucose as energy for the body at a time when sucrose has already been digested and would
no longer supply energy. The overall digestion in the small intestine is virtually complete, as
demonstrated by recovery studies.
Complete absorption in the small intestine means that isomaltulose provides the same amount of
calories as all digestible carbohydrates (sugars and starches 4 kcal/g) and is equally well tolerated (as
no significant amount reaches the large intestine no gastrointestinal distress occurs).
The slow but complete hydrolysis and absorption leads to a low blood glucose response (Glycemic Index
= 32) and a low insulinemic response (Insulinemic
Index = 30). This provides a tool for food
manufacturers to prepare low glycemic food
products (e.g. beverages etc) that help the
consumers in their food choice to achieve a lower
insulin day-profile which is desirable as explained in
the following: The hormone insulin has many
functions in the body, e.g. it down-regulates high
blood glucose levels by ìopening the doorî for
cellular glucose uptake. At the same time insulin
promotes fat storage and inhibits fat burning. High
levels of insulin over a long period of time are
discussed to contribute to obesity and the
development of diabetes.
Consistent with the lower insulin response after
intake of isomaltulose, it was demonstrated that fat
oxidation was increased (measurements of the
respiratory quotient). This may have an effect on
body fat.
0 30 60 90 120
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BENEO GmbH68165 MannheimGermanywww.BENEO-Group.comGeneral Management: Hildegard BauerDr. Matthias MoserYves Servotte
Court of Registration: County Court MannheimNo. HRB 701800VAT Identification Number DE 253 691 060Bank Details: Deutsche Bank AG Mannheim
Acc. 40651200 Bank Code 670 700 10SWIFT: DEUT DE SMIBAN DE94 6707 0010 0040 6512 00
Plasma glucose change (mmol/L)
5
4
3
2
1
0
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Time (min)
Sucrose
Palatinoseô
Blood glucose curves of Palatinoseô or sucrose (50g)
determined in 10 healthy volunteers at the Sydney Universityís
Glycaemic Index Research Service (2002), (mean±SD).
1 Commission Decision 2005/581/EC of 25 July 2005 authorising the placing on the market of isomaltulose as a novel food or novel
food ingredient under Regulation (EC) No 258/97 of the European Parliament and of the Council (notified under document number
C(2005) 2776). OJ L 199, 29.7.2005, p. 90ñ91.