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The influence of the place-value structure of the Arabic number ...

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portion <strong>of</strong> <strong>the</strong> superior frontal gyrus, both bilaterally. A fur<strong>the</strong>r activation cluster was<br />

observed in <strong>the</strong> right medial temporal gyrus (Figure 2A, Table 6).<br />

Possible > impossible: No region exhibited an increase in activation for this contrast at<br />

<strong>the</strong> voxelwise uncorrected threshold <strong>of</strong> p = .01.<br />

Impossible > possible: Increased activation in <strong>the</strong> right ventro-lateral prefrontal cortex<br />

was observed for triplets impossible to bisect by an integer (BA47, Talairach coordinates: 40,<br />

20, -4, k = 10, t(16) = 5.99, p < .001, uncorrected, see Figure 2B and Table 6).<br />

Multiplicative > non-multiplicative: When <strong>the</strong> triplet was part <strong>of</strong> a multiplication<br />

table, <strong>the</strong> left angular gyrus and a small portion <strong>of</strong> prefrontal cortex was specifically activated<br />

(Figure 3, Table 7).<br />

Table 5: Brain areas activated by problem size (all p < 0.001, voxelwise uncorrected)<br />

Large sum > small sum<br />

Region<br />

Talairach coordinates<br />

x, y, z<br />

t-<strong>value</strong><br />

df=16<br />

BA<br />

Cluster<br />

size k<br />

Right extrastriate cortex 33, -90, -3 6.28 19 602<br />

Left strate cortex -9, -81, 6 5.94 17/18 -<br />

Left extrastriate cortex -15, -93, 0 5.03 19 -<br />

Right strate cortex 3, -84, 15 5.07 17/18 -<br />

Left temporo-occipital junction -42, -53, -20 5.82 19/37 28<br />

cerebellum -6, -74, -19 7.49 - 85<br />

Small sum > large sum<br />

Left inferior parietal cortex -48, -62, 47 5.50 39 66<br />

Right inferior parietal cortex 53, -69, 23 5.33 39 26<br />

189

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