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Low_resolution_Thesis_CDD_221009_public - Visual Optics and ...

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HYBRID PORCINE/PLASTIC MODEL<br />

6.4.2. Validation of the POSTERIOR surface<br />

Table 6.2 shows the nominal <strong>and</strong> estimated posterior radii of curvature in the hybrid<br />

porcine/plastic eye model. Each data is the average of the different eyes with similar<br />

posterior plastic cornea. There is a good correlation between nominal <strong>and</strong> estimated<br />

radius, although there is higher bias (underestimation) than for the anterior cornea<br />

(150 to 400 μm). Despite the low accuracy (the absolute values are not recovered<br />

exactly), the repeatability is good (below 100 m), considering that these are<br />

individual measurements (non-averaged) of hybrid eyes whose anterior surface varies<br />

across measurements.<br />

6.4.3. Correlation between anterior <strong>and</strong> posterior surfaces<br />

6.4.3.1. Radius<br />

Correlations between anterior <strong>and</strong> posterior corneal surface were performed to assess<br />

that the optical distortion correction was successfully applied. Statistically significant<br />

correlations between the posterior (fixed) corneal surface <strong>and</strong> the anterior (variable, as<br />

dependent from the specimen <strong>and</strong> pressure exerted by the piston) would be indicative<br />

of artifacts in the correction. This is particularly critical in the current study, when the<br />

same eyes are evaluated before <strong>and</strong> after a change in the anterior cornea.<br />

Figure 6.4 shows the anterior radius vs. the deviations in posterior radius for all<br />

the posterior corneal samples <strong>and</strong> all the porcine corneas. Our hybrid porcine/plastic<br />

model corneas showed a wide range of anterior radii (from 8.0 to 9.6 mm) for the<br />

different combinations of anterior porcine corneas <strong>and</strong> posterior plastic surfaces. A z-<br />

test showed no correlation between anterior radius vs. deviations in posterior radius<br />

(p>0.26) for all measurements (averaged across identical conditions). Additional z-<br />

tests between anterior <strong>and</strong> posterior corneal radius for each plastic back surface also<br />

showed no correlation (p>0.6). These results indicate that the radius of the anterior<br />

surface does not affect the radius measured of the posterior surface.<br />

Fig. 6.4. Measurements of Radii<br />

6.4.3.2. Astigmatism<br />

Also, the anterior corneas typically showed significant amount of astigmatism (1.9 ±<br />

1.0 D) with preferential orientations in the vertical <strong>and</strong> horizontal directions, while the<br />

estimated astigmatism for the posterior surface was much lower (0.31 ± 0.15 D), with<br />

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