Low_resolution_Thesis_CDD_221009_public - Visual Optics and ...

More documents

Recommendations

Info

$XXX Congress of the European Society of Cataract and Refractive ...$

CHAPTER 7 We compared the changes in patients that underwent refractive surgery (Fig. 7.4 (A-F)), with normal control eyes, measured following a similar time-course (Fig. 7.4 (G-L)). In some cases, we observed statistically significant changes in control eyes between measurements separated one day or one week, although no treatment had been applied between the measurements. Very interestingly, left and right eyes of the same subject (in all patients and all but one control subject) follow the same trends with time. 7.4.4. Difference between vertical and horizontal radii and asphericities The results reported above correspond to radii and asphericities obtained from a fit of the topographies to rotationally symmetric ellipsoids. We have also fitted the topographies to more general non-rotationally symmetric ellipsoids, and analyzed the vertical and horizontal radii and asphericities separately. We did not find statistically significant meridional differences in asphericity (Fig. 7.5 (C, D)). However, the average radius of curvature shows statistically significant meridional differences: while the horizontal radius does not change at any time point (Fig. 7.5 (A)), the vertical radius of curvature suffers a statistically significant change one day after surgery (Fig. 7.5 (B), R y = 47 m, p = 0.004). This meridional difference is equivalent to a posterior astigmatism of 0.9 D (and an effective astigmatism of 0.037 D), and is responsible for the near-significant change of the average radius of curvature reported before (Fig. 7.3 (A)). This meridional change cannot be attributed to a different variability in the vertical direction for this instrument, as seen from the validation experiments. No meridional differences were found in control subjects. Fig. 7.5: Changes of average horizontal and vertical radii of curvature (A, B) and asphericity (C, D). Gray dots: Patients measured the three times. Black squares: All patients. Error bars indicate the 98.3% confidence interval. Number of eyes per point is the same as in Fig. 7.3. Figure 7.6 shows histograms of changes between pre-operative and all post-operative measurements for all control eyes (A, B) and all surgical eyes (C, D). Changes in control subjects follow normal distributions (according to Jarque-Bera normality test) 178
ANTERIOR AND POSTERIOR CORNEAL ELEVATION MAPS AFTER REFRACTIVE SURGERY for both meridians (Fig. 7.6 (A, B)). Both distributions have zero mean (Student’s t test), and although there is more dispersion for the vertical meridian, there is no statistically significant difference between the two standard deviations (p = 0.06, Ansari-Bradley test). We conclude that there is no statistically significant difference between horizontal and vertical radius of curvature for control subjects. Changes in patients are not normally distributed (Fig. 7.6 (C, D)), and their standard deviations are slightly greater than the standard deviation of changes in controls for both meridians. We observe no statistically significant shift for the horizontal radius (Fig. 7.6 (C)), but there is a very significant shift of the vertical radius one day after surgery, which disappears afterwards (Fig. 7.6 (D)). Fig. 7.6: (A) Histogram of changes in horizontal radius of curvature of the posterior corneal surface in all control subjects (all changes at 1 day and 1 week are included in the histogram). (B) The same as (A), for the vertical radius of curvature. (C) Histogram of changes in horizontal radius of curvature of the posterior corneal surface in all patients, between pre-operative measurement and all post-operative ones (1day, 1 week and 1 month). (D) The same as (B), for the vertical radius of curvature. 7.4.5. Correlation of the posterior corneal changes with different parameters We tested correlations between posterior corneal changes in radius of curvature, asphericity or central elevation with the attempted correction, change of pachymetry, pre-operative central pachymetry, post-operative central pachymetry or post-operative residual bed thickness. We tested all these correlations separately for changes 1 day, 1 week and 1 month after surgery. Of those correlations, only the correlation between attempted correction and posterior corneal apex shift one week after surgery showed a statistically significant correlation (r = 0.665, p = 0.0005). We only found nearsignificant correlations (p-value ranging from 0.04 to 0.051) between attempted correction and posterior corneal apex shift one day after surgery, and pachymetry, posterior apex shift, and radius of the posterior surface one week after surgery. These correlations disappear if eyes with attempted corrections greater than -6 D are removed from the calculation. 179
Page 1:
Doctoral thesis Corneal Ablation an
Page 5 and 6:
Contents Corneal Ablation and Conta
Page 7 and 8:
2.2.1. Fitting surfaces............
Page 9 and 10:
5.3.3. Ablation efficiency factors
Page 11:
10.5. DISCUSSION...................
Page 14 and 15:
We thank José Antonio Sánchez-Gil
Page 16 and 17:
BOZR Back Optic Zone Radius BCVA Be
Page 19 and 20:
INTRODUCTION 1.1. MOTIVATION The fr
Page 21 and 22:
INTRODUCTION 1.2. THE OPTICAL SYSTE
Page 23 and 24:
INTRODUCTION Myopia is a very commo
Page 25 and 26:
INTRODUCTION a point focus: the dif
Page 27 and 28:
INTRODUCTION system, and tilt repre
Page 29 and 30:
INTRODUCTION term Z 0 2 stands for
Page 31 and 32:
INTRODUCTION which image was shadow
Page 33 and 34:
INTRODUCTION The defocus Zernike te
Page 35 and 36:
INTRODUCTION 1.4.6.3. Internal Aber
Page 37 and 38:
INTRODUCTION 1.5.2.3. Alternating v
Page 39 and 40:
INTRODUCTION and further-more, at l
Page 41 and 42:
INTRODUCTION alcohol is used to loo
Page 43 and 44:
INTRODUCTION changes in reflectivit
Page 45 and 46:
INTRODUCTION Marcos et al. (Marcos
Page 47 and 48:
INTRODUCTION 1.7.3. Ablation effici
Page 49 and 50:
INTRODUCTION corneal surface may be
Page 51 and 52:
INTRODUCTION Algorithm design: The
Page 53 and 54:
INTRODUCTION contact lenses the fie
Page 55 and 56:
INTRODUCTION 1.10.1. Tear studies A
Page 57 and 58:
INTRODUCTION there are still many u
Page 59 and 60:
INTRODUCTION 6. Evaluation and unde
Page 61 and 62:
METHODS 2Chapter Chapter 2 - Method
Page 63 and 64:
METHODS 2.1. MEASUREMENT OF OPTICAL
Page 65 and 66:
METHODS In both profilometers, cust
Page 67 and 68:
METHODS The measurement method that
Page 69 and 70:
METHODS Fig. 2. 9. Set of points in
Page 71 and 72:
METHODS Slit lamp Scheimpflug Camer
Page 73 and 74:
METHODS representing the deviation
Page 75 and 76:
METHODS 2.2.2.2. Ablation pattern f
Page 77 and 78:
METHODS direction. These calculatio
Page 79 and 80:
METHODS eye through the whole pupil
Page 81 and 82:
METHODS (1993) power thresholds for
Page 83 and 84:
METHODS alignment (frontal-illumina
Page 85 and 86:
METHODS Fig. 2. 24. Example frame f
Page 87 and 88:
METHODS 4) New image processing too
Page 89 and 90:
METHODS Fig. 2. 28. Corrected entra
Page 91 and 92:
METHODS Badal lens, corresponds to
Page 93:
METHODS Each VA measurement consist
Page 99:
REFRACTIVE SURGERY PMMA MODEL 3.1.
Page 102 and 103:
CHAPTER 3 optimization of refractiv
Page 104 and 105:
CHAPTER 3 These data demonstrate th
Page 106 and 107:
CHAPTER 3 regression line, since it
Page 108 and 109:
CHAPTER 3 Figure 3.3 shows one of t
Page 110 and 111:
CHAPTER 3 Ablation efficiency facto
Page 112 and 113:
CHAPTER 3 considering the same set
Page 114 and 115:
CHAPTER 3 3.5.3 Impact of correctio
Page 117:
ABLATION PROPERTIES OF FILOFOCON A
Page 121 and 122:
Page 123 and 124:
Page 125 and 126:
Page 127 and 128: ABLATION PROPERTIES OF FILOFOCON A
Page 133: ABLATION PROPERTIES OF FILOFOCON A
Page 137: OPTIMIZED LASER PLATFORMS 5.1 ABSTR
Page 140 and 141: CHAPTER 5 pulses. Fluence, repetiti
Page 142 and 143: CHAPTER 5 ablations. The slit-confo
Page 144 and 145: CHAPTER 5 (Anera et al., 2003): d S
Page 146 and 147: CHAPTER 5 asymmetries also appeared
Page 148 and 149: CHAPTER 5 5.3.4. Ablation patterns
Page 150 and 151: CHAPTER 5 a) b) : 6.5 mm c) Fig. 5.
Page 152 and 153: CHAPTER 5 achieve proper reflection
Page 154 and 155: CHAPTER 5 Both the ablation algorit
Page 157: HYBRID PORCINE/PLASTIC MODEL 6.1. A
Page 160 and 161: CHAPTER 6 6.3.1. Hybrid porcine-pla
Page 162 and 163: CHAPTER 6 is detected. Therefore, i
Page 164 and 165: CHAPTER 6 no preferential orientati
Page 167: ANTERIOR AND POSTERIOR CORNEAL ELEV
Page 171 and 172: ANTERIOR AND POSTERIOR CORNEAL ELEV
Page 177: ANTERIOR AND POSTERIOR CORNEAL ELEV
Page 183: 183
Page 187: SOFT CONTACT LENS FITTING USING MOD
Page 191 and 192: SOFT CONTACT LENS FITTING USING MOD
Page 194: ON-EYE OPTICAL PERFORMANCE OF RIGID
Page 198 and 199: ON-EYE OPTICAL PERFORMANCE OF RIGID
Page 212: SOFT MONOFOCAL AND MULTIFOCAL CONTA
Page 216: SOFT MONOFOCAL AND MULTIFOCAL CONTA
Page 220 and 221: CORRELATION BETWEEN RADIUS AND ASPH
Page 228 and 229:
CORRELATION BETWEEN RADIUS AND ASPH
Page 230:
CONCLUSIONS Conclusions This thesis
Page 233 and 234:
CONCLUSIONS 5We have developed a pr
Page 236:
CONCLUSIONS LIST OF METHODOLOGICAL
Page 240 and 241:
CONCLUSIONS FUTURE RESEARCH LINES T
Page 242 and 243:
CONCLUSIONS LIST OF PUBLICATIONS AN
Page 244 and 245:
REFERENCES References AIZAWA, D., S
Page 246 and 247:
REFERENCES PHOTODECOMPOSITION (APD)
Page 248 and 249:
REFERENCES DORRONSORO, C., CANO, D.
Page 250 and 251:
REFERENCES GISPETS, J., ARJONA, M.
Page 252 and 253:
REFERENCES KOPF, M., YI, F., ISKAND
Page 254 and 255:
REFERENCES MARCOS, S., DORRONSORO,
Page 256 and 257:
REFERENCES NOVO, A., PAVLOPOULOS, G
Page 258 and 259:
REFERENCES SAKIMOTO, T., ROSENBLATT
Page 260:
REFERENCES WANG, L., DAI, E., KOCH,
Page 263 and 264:
RESÚMENES pacientes reales fue com
Page 265 and 266:
RESÚMENES experimentales de cirug
Page 267 and 268:
RESÚMENES cada punto de las cornea
Page 269 and 270:
RESÚMENES plástico medidas anteri
Page 272 and 273:
RESÚMENES 8 Evaluación óptica de
Page 274 and 275:
RESÚMENES 9 Prestaciones ópticas
Page 276 and 277:
RESÚMENES 10 Calidad óptica y cal
Page 278:
RESÚMENES A Correlación entre rad
Page 281 and 282:
CONCLUSIONES clínicos. La descripc
Page 283 and 284:
CONCLUSIONES 12 Las superficies ocu
Page 286:
CONCLUSIONES IMPLICACIONES DE ESTA
Page 289 and 290:
CONCLUSIONES contribuyen a la compr
Page 291:
(y muchísimo más difícil). Me da
show all

Low_resolution_Thesis_CDD_221009_public - Visual Optics and ...

Create successful ePaper yourself

Delete template?

Save as template?