Low_resolution_Thesis_CDD_221009_public - Visual Optics and ...

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$XXX Congress of the European Society of Cataract and Refractive ...$

3.5.3 Impact of correction factors on post-operative corneal shape and aberrations.........................................................................................................114 3.5.4. The role of corneal biomechanics............................................................114 3.6. CONCLUSIONS..................................................................................................115 3.7. OUTLOOK.........................................................................................................115 CHAPTER 4 - EVALUATION OF THE ABLATION PROPERTIES OF A NEW MATERIAL (FILOFOCON A) FOR A CORNEAL MODEL............................117 4.1 ABSTRACT ........................................................................................................119 4.2 INTRODUCTION .................................................................................................121 4.3. METHODS ........................................................................................................122 4.3.1 Samples .....................................................................................................122 4.3.2 Estimation of optical properties................................................................122 4.3.3 Laser ablation set-up ................................................................................122 4.3.4. Crater depth measurement by non-contact profilometry .........................123 4.3.5 Data analysis ............................................................................................123 4.3.6 Microscopic structure of the ablation................................................................. 123 4.4. RESULTS ..........................................................................................................123 4.4.1. Optical properties ....................................................................................123 4.4.2. Ablation profiles.......................................................................................124 4.4.3. Linearity of ablation depth with pulse number ........................................125 4.4.4 Beer Lambert law: ablation threshold and absorption coefficient ...........126 4.4.5 Microscopic structure of the ablation craters...........................................128 4.5. DISCUSSION .....................................................................................................129 4.5.1. Measuring a laser ablation pattern: energy to depth relationship ..........130 4.5.2. Measuring ablation efficiency..................................................................131 4.5.3. Central islands in PMMA ........................................................................132 4.5.4. Absorption coefficient ..............................................................................132 4.6. CONCLUSIONS..................................................................................................132 4.7. OUTLOOK.........................................................................................................133 CHAPTER 5 - EVALUATION OF ABLATION PROFILES, POST- OPERATIVE OUTCOMES AND ABLATION EFFICIENCY FACTORS OF DIFFERENT OPTIMIZED LASER PLATFORMS............................................135 5.1 ABSTRACT ........................................................................................................137 5.2 INTRODUCTION .................................................................................................139 5.2. METHODS ........................................................................................................139 5.2.1. Lasers.......................................................................................................139 5.2.2. Artificial eyes ...........................................................................................140 5.2.3. Ablation protocol with clinical lasers......................................................140 5.2.4. Pre- and Post- operative measurements ..................................................141 5.2.5. Data analysis ...........................................................................................142 5.2.5.1. Extracting the ablation patterns...................................................................... 142 5.2.5.2. Computing the laser efficiency effects........................................................... 143 5.2.5.3. Impact on cornea............................................................................................ 143 5.2.5.4. Asphericities and spherical aberration............................................................ 144 5.3. RESULTS ..........................................................................................................144 5.3.1. Pre-operative shape measurements .........................................................144 5.3.2. Ablation patterns on plastic .....................................................................145 8
5.3.3. Ablation efficiency factors on plastic....................................................... 146 5.3.4. Ablation patterns in cornea ..................................................................... 148 5.3.5. Correction factors for efficiency effects in cornea .................................. 149 5.3.6. Optical outcomes in cornea..................................................................... 149 5.4. DISCUSSION..................................................................................................... 151 5.4.1. Toward an optimized ablation pattern..................................................... 152 5.4.2. Ablations on Filofocon A: a method for laser calibration....................... 152 5.5. CONCLUSIONS ................................................................................................. 153 CHAPTER 6 - HYBRID PORCINE/PLASTIC MODEL FOR THE STUDY OF THE BACK SURFACE OF THE CORNEA ........................................................ 155 6.1. ABSTRACT....................................................................................................... 157 6.2. INTRODUCTION................................................................................................ 159 6.3. METHODS ........................................................................................................ 159 6.3.1. Hybrid porcine-plastic eye model............................................................ 160 6.3.2. Measurements: validation on model eyes................................................ 160 6.4. RESULTS.......................................................................................................... 162 6.4.1. Validation of the ANTERIOR surface...................................................... 162 6.4.2. Validation of the POSTERIOR surface.................................................... 163 6.4.3. Correlation between anterior and posterior surfaces ............................. 163 6.4.3.1. Radius ............................................................................................................ 163 6.4.3.2. Astigmatism ................................................................................................... 163 6.4.3.3. Asphericities................................................................................................... 164 6.5. DISCUSSION..................................................................................................... 164 6.6. CONCLUSIONS ................................................................................................. 164 6.7. OUTLOOK ........................................................................................................ 165 CHAPTER 7 - CHANGES IN THE ANTERIOR AND POSTERIOR CORNEAL ELEVATION MAPS WITH REFRACTIVE SURGERY.................................. 167 7.1. ABSTRACT....................................................................................................... 169 7.2. INTRODUCTION................................................................................................ 171 7.3. METHODS ........................................................................................................ 171 7.3.1. Subjects.................................................................................................... 171 7.3.2. Surgical procedure .................................................................................. 172 7.3.3. Measurements: patients and control eyes................................................ 172 7.3.4. Data Analysis........................................................................................... 172 7.3.4.1. Difference maps and corneal elevation .......................................................... 173 7.3.4.2. Comparison of Matlab and Pentacam software fitting parameters ................. 174 7.3.4.3. Significance of changes.................................................................................. 174 7.4 RESULTS........................................................................................................... 174 7.4.1. Repeatability of the posterior corneal surface measurements................. 174 7.4.2. Change of the anterior corneal surface with LASIK surgery .................. 175 7.4.3. Change of the posterior corneal surface as a function of time................ 175 7.4.4. Difference between vertical and horizontal radii and asphericities........ 178 7.4.5. Correlation of the posterior corneal changes with different parameters 179 7.5. DISCUSSION..................................................................................................... 180 7.6. CONCLUSIONS ................................................................................................. 181 7.7. OUTLOOK ........................................................................................................ 182 9
Page 1: Doctoral thesis Corneal Ablation an
Page 5 and 6: Contents Corneal Ablation and Conta
Page 7: 2.2.1. Fitting surfaces............
Page 11: 10.5. DISCUSSION...................
Page 14 and 15: We thank José Antonio Sánchez-Gil
Page 16 and 17: BOZR Back Optic Zone Radius BCVA Be
Page 19 and 20: INTRODUCTION 1.1. MOTIVATION The fr
Page 21 and 22: INTRODUCTION 1.2. THE OPTICAL SYSTE
Page 23 and 24: INTRODUCTION Myopia is a very commo
Page 25 and 26: INTRODUCTION a point focus: the dif
Page 27 and 28: INTRODUCTION system, and tilt repre
Page 29 and 30: INTRODUCTION term Z 0 2 stands for
Page 31 and 32: INTRODUCTION which image was shadow
Page 33 and 34: INTRODUCTION The defocus Zernike te
Page 35 and 36: INTRODUCTION 1.4.6.3. Internal Aber
Page 37 and 38: INTRODUCTION 1.5.2.3. Alternating v
Page 39 and 40: INTRODUCTION and further-more, at l
Page 41 and 42: INTRODUCTION alcohol is used to loo
Page 43 and 44: INTRODUCTION changes in reflectivit
Page 45 and 46: INTRODUCTION Marcos et al. (Marcos
Page 47 and 48: INTRODUCTION 1.7.3. Ablation effici
Page 49 and 50: INTRODUCTION corneal surface may be
Page 51 and 52: INTRODUCTION Algorithm design: The
Page 53 and 54: INTRODUCTION contact lenses the fie
Page 55 and 56: INTRODUCTION 1.10.1. Tear studies A
Page 57 and 58: INTRODUCTION there are still many u
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INTRODUCTION 6. Evaluation and unde
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METHODS 2Chapter Chapter 2 - Method
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METHODS 2.1. MEASUREMENT OF OPTICAL
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METHODS In both profilometers, cust
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METHODS The measurement method that
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METHODS Fig. 2. 9. Set of points in
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METHODS Slit lamp Scheimpflug Camer
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METHODS representing the deviation
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METHODS 2.2.2.2. Ablation pattern f
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METHODS direction. These calculatio
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METHODS eye through the whole pupil
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METHODS (1993) power thresholds for
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METHODS alignment (frontal-illumina
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METHODS Fig. 2. 24. Example frame f
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METHODS 4) New image processing too
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METHODS Fig. 2. 28. Corrected entra
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METHODS Badal lens, corresponds to
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METHODS Each VA measurement consist
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REFRACTIVE SURGERY PMMA MODEL 3.1.
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CHAPTER 3 optimization of refractiv
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CHAPTER 3 These data demonstrate th
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CHAPTER 3 regression line, since it
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CHAPTER 3 Figure 3.3 shows one of t
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CHAPTER 3 Ablation efficiency facto
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CHAPTER 3 considering the same set
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CHAPTER 3 3.5.3 Impact of correctio
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ABLATION PROPERTIES OF FILOFOCON A
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OPTIMIZED LASER PLATFORMS 5.1 ABSTR
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CHAPTER 5 pulses. Fluence, repetiti
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CHAPTER 5 ablations. The slit-confo
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CHAPTER 5 (Anera et al., 2003): d S
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CHAPTER 5 asymmetries also appeared
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CHAPTER 5 5.3.4. Ablation patterns
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CHAPTER 5 a) b) : 6.5 mm c) Fig. 5.
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CHAPTER 5 achieve proper reflection
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CHAPTER 5 Both the ablation algorit
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HYBRID PORCINE/PLASTIC MODEL 6.1. A
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CHAPTER 6 6.3.1. Hybrid porcine-pla
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CHAPTER 6 is detected. Therefore, i
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CHAPTER 6 no preferential orientati
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ANTERIOR AND POSTERIOR CORNEAL ELEV
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183
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SOFT CONTACT LENS FITTING USING MOD
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SOFT CONTACT LENS FITTING USING MOD
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ON-EYE OPTICAL PERFORMANCE OF RIGID
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SOFT MONOFOCAL AND MULTIFOCAL CONTA
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SOFT MONOFOCAL AND MULTIFOCAL CONTA
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CORRELATION BETWEEN RADIUS AND ASPH
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CONCLUSIONS Conclusions This thesis
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CONCLUSIONS 5We have developed a pr
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CONCLUSIONS LIST OF METHODOLOGICAL
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CONCLUSIONS FUTURE RESEARCH LINES T
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CONCLUSIONS LIST OF PUBLICATIONS AN
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REFERENCES References AIZAWA, D., S
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REFERENCES PHOTODECOMPOSITION (APD)
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REFERENCES DORRONSORO, C., CANO, D.
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REFERENCES GISPETS, J., ARJONA, M.
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REFERENCES KOPF, M., YI, F., ISKAND
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REFERENCES MARCOS, S., DORRONSORO,
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REFERENCES NOVO, A., PAVLOPOULOS, G
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REFERENCES SAKIMOTO, T., ROSENBLATT
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REFERENCES WANG, L., DAI, E., KOCH,
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RESÚMENES pacientes reales fue com
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RESÚMENES experimentales de cirug
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RESÚMENES cada punto de las cornea
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RESÚMENES plástico medidas anteri
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RESÚMENES 8 Evaluación óptica de
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RESÚMENES 9 Prestaciones ópticas
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RESÚMENES 10 Calidad óptica y cal
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RESÚMENES A Correlación entre rad
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CONCLUSIONES clínicos. La descripc
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CONCLUSIONES 12 Las superficies ocu
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CONCLUSIONES IMPLICACIONES DE ESTA
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CONCLUSIONES contribuyen a la compr
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(y muchísimo más difícil). Me da
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