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Monday AM 1 Opening Session 2011 Mansfield Lecture ... - ISMRM

Monday AM 1 Opening Session 2011 Mansfield Lecture ... - ISMRM

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Friday <strong>AM</strong><br />

11:30 769. Comparative Oxidative Demands in Cortex & Subcortex Revealed By High Field Calibrated fMRI<br />

Basavaraju G. Sanganahalli 1,2 , Peter Herman 1,2 , Douglas L. Rothman 2,3 , Hal Blumenfeld 2,4 , Fahmeed Hyder 2,3<br />

1 Diagnostic Radiology, Yale University, New Haven, CT, USA; 2 Quantitative Neuroscience with Magnetic Resonance in Medicine<br />

(QNMR), Yale University, New Haven, CT, USA; 3 Diagnostic Radiology & Biomedical Engineering, Yale University, New Haven,<br />

CT, USA; 4 Neurology, Neurosurgery, Neuroscience, Yale University, New Haven, CT, USA<br />

11:42 770. The Ratio of CBF to CMRO 2 Change with Brain Activation Remains Unchanged between Simple & Complex<br />

Stimuli in the Human Visual Cortex<br />

Valerie Griffeth 1 , Richard Buxton 2<br />

1 Department of Bioengineering, UC San Diego, La Jolla, CA, USA; 2 Department of Radiology, UC San Diego, La Jolla, CA, USA<br />

11:54 771. Calibration & Validation of TRUST MRI for the Estimation of Cerebral Blood Oxygenation<br />

Hanzhang Lu 1 , Feng Xu 1 , Ksenija Grgac 2,3 , Peiying Liu 1 , Qin Qin 2,3 , Peter van Zijl 2,3<br />

1 Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA; 2 Department of<br />

Radiology, Johns Hopkins University, Baltimore, MD, USA; 3 F.M. Kirby Center, Kennedy Krieger Institute, Baltimore, MD, USA<br />

12:06 772. A Generalized Procedure for Calibrated MRI Incorporating Hyperoxia & Hypercapnia<br />

Claudine Joëlle Gauthier 1 , 2 , Richard D. Hoge 1 , 2<br />

1 Physiology/Biomedical Engineering, Université de Montréal, Montreal, Quebec, Canada; 2 CRIUGM, Montreal, Quebec, Canada<br />

12:18 773. Evolution of the Dynamic Changes in Cerebral Oxidative Metabolism Evoked by Somato-Sensory Stimulation<br />

Alberto L. Vazquez 1 , Mitsuhiro Fukuda 1 , Seong-Gi Kim 1<br />

1 Radiology, University of Pittsburgh, Pittsburgh, PA, USA<br />

Normal Aging Brain<br />

Room 710A 10:30-12:30 Moderators: Christopher P. Hess & Patrik Zamecnik<br />

10:30 774. Age Effects on the Amplitude & Frequency of Resting-State BOLD Fluctuations<br />

J. Jean Chen 1,2 , Tyler D. Triggs 1 , H. Diana Rosas 1,3 , David H. Salat 1,2<br />

1 Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA; 2 Department of<br />

Radiology, Massachusetts General Hospital, Boston, MA, USA; 3 Department of Neurology, Massachusetts General Hospital, Boston,<br />

MA, USA<br />

10:42 775. Association between Cerebral Blood Flow & Age-Related Changes in White Matter Microstructure<br />

J. Jean Chen 1,2 , H. Diana Rosas 1,3 , David H. Salat 1,2<br />

1 Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA; 2 Department of<br />

Radiology, Massachusetts General Hospital, Boston, MA, USA; 3 Department of Neurology, Massachusetts General Hospital, Boston,<br />

MA, USA<br />

10:54 776. Aging Effect on Human Brain Transverse Relaxation Since Preadolescence<br />

Jianli Wang 1 , Megha Patel 1 , Deborah Dossick 1 , Michele L. Shaffer 2 , Christopher W. Weitekamp 1 , Xiaoyu Sun 1 , Jeffrey<br />

Vesek 1 , Paul J. Eslinger 3 , David J. Jill 3 , James R. Connor 4 , Qing X. Yang 1,4<br />

1 Radiology, Penn State College of Medicine, Hershey, PA, USA; 2 Public Health Sciences, Penn State College of Medicine, Hershey,<br />

PA, USA; 3 Neurology, Penn State College of Medicine, Hershey, PA, USA; 4 Neurosurgery, Penn State College of Medicine, Hershey,<br />

PA, USA<br />

11:06 777. Genetic Influences on White Matter Microstructure in 280 Twins Scanned with 4 Tesla High Angular<br />

Resolution Diffusion Imaging (HARDI)<br />

Agatha D. Lee 1 , Natasha Lepore 2 , Caroline C. Brun 3 , Marina Barysheva, Arthur Toga, Katie L. McMaho 4 , Greig I. de<br />

Zubicaray 5 , Nicholas G. Martin, Margaret Wright, Paul M. Thompson<br />

1 Neurology, LONI-UCLA, Los Angeles, CA, USA; 2 CHLA -USC; 3 UPENN; 4 Centre for Magnetic Resonance, University of<br />

Queensland; 5 Queensland Institute of Medical Research,<br />

11:18 778. Preliminary Evidence of Increased Brain Acetate Uptake & Oxidation in Heavy Drinkers Probed by 13 C-MRS<br />

Lihong Jiang 1 , Barbara Gulanski 2 , Stuart Weinzimer 3 , Ismene Petrakis 3 , Elizabeth Guidone 3 , Julia Koretski 3 , Graeme<br />

Mason<br />

1 Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA; 2 Internal Medicine, Yale University School of<br />

Medicine; 3 Psychiatry, Yale University School of Medicine<br />

11:30 779. Age & Gender Related Alterations in Brain Perfusion Dynamics<br />

Yinan Liu 1,2 , Xiaoping Zhu 1 , David Feinberg 2,3 , Matthias Guenther 4,5 , Howard Rosen 6 , Michael W. Weiner 1,2 , Norbert<br />

Schuff 1,2<br />

1 Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA, USA;<br />

2 Department of Radiology & Biomedical Imaging, University of California, San Francisco, CA, USA; 3 Advanced MRI Technology<br />

106

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