Poster <strong>Session</strong>s 250 1 Institute for Women's Health, University College London, London, United Kingdom; 2 Medical Physics & Bioengineering, University College Hospitals, London, United Kingdom; 3 UCL Institute of Neurology, London, United Kingdom 2290. Relation Between 1 H & 31 P MRS Biomarkers & Immunohistochemical Markers of Cell Death & Inflammation in a Perinatal Asphyxia Piglet Model Nicola Jayne Robertson 1 , Manigandan Chandrasekaran 1 , Stuart Faulkner 1 , Alan Bainbridge 2 , Dorottya Kelen 1 , Sudhin Thayyil 1 , Ernest Cady 1 , Xavier Golay 3 , Gennadij Raivich 1 1 Institute for Women's Health, University College London, London, United Kingdom; 2 Medical Physics and Bioengineering, University College Hospitals, London, United Kingdom; 3 UCL Institute of Neurology, United Kingdom 2291. In Vivo 9.4T 1 H MRS for Evaluation of Brain Metabolic Changes in the Ts65Dn Mouse Model of Down Syndrom Jean-Claude Beloeil 1 , William Même 1 , Nadir Yousfi 1 , Patricia Lospez-Pereira 2 , yann Hérault 2,3 , Sandra Même 1 1 CBM CNRS UPR4301, Orléans, France; 2 TA<strong>AM</strong> CNRS UPS44, Orléans, France; 3 IGBMC, Strasbourg, France 2292. Non-Invasive Magnetic Resonance Spectroscopy Biomarkers of Oxidative Stress Following Traumatic Brain Injury William Miles Brooks 1,2 , Janna Harris, Hung-Wen Yeh 3 , In-Young Choi 1 , Sang-Pil Lee, 4 1 Hoglund Brain Imaging Center, University of Kansas, Kansas City, KS, United States; 2 Neurology, University of Kansas, Kansas City, KS, United States; 3 Biostatistics, University of Kansas, United States; 4 Molecular & Integrative Physiology, University of Kansas 2293. Effects of Nitrones in Rodent Glioma Models Assessed by 1 H MR Spectroscopy Ting He 1 , Sabrina Doblas 1 , Debra Saunders 1 , Rebba Casteel 1 , Robert Floyd 2 , Rheal Towner 1 1 Advanced Magnetic Resonance Center, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States; 2 Experimental Thearapeutics, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States 2294. Does the Warburg Effect Exist In Vivo? Analyzing Glucose Metabolism in FDG-PET-Positive Tumors by 13 C- NMR Spectroscopy Isaac Marin-Valencia 1 , Steve K. Cho 2 , Levi B. Good 2 , Michael Long 3 , Xiankai Sun 3 , Juan M. Pascual 2,4 , Mark Jeffrey 3 , Elizabeth A. Maher 5 , Craig R. Malloy 3,5 , Robert M. Bachoo 2 , Ralph J. DeBerardinis 1 1 Pediatrics, UT Southwestern Medical Center, Dallas, TX, United States; 2 Neurology, UT Southwestern Medical Center, Dallas, TX, United States; 3 Radiology, UT Southwestern Medical Center, Dallas, TX, United States; 4 Physiology, UT Southwestern Medical Center, Dallas, TX, United States; 5 Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States 2295. Stress During Gestation & Exposure to an Indirect Cannabinoid Agonist During Adolescence Alter Brain Metabolism in Mice Rossella Canese 1 , Simone Macrì 1 , Chiara Ceci 1 , Emiliano Surrentino 1 , Giovanni Laviola 1 1 Cell Biology & Neurosciences Dept., Istituto Superiore di Sanità, Rome, RM, Italy 2296. Alternative Pathways of Glucose Metabolism in a Mouse Model of Human Brain Tumors Isaac Marin-Valencia 1 , Steve K. Cho 2 , Levi B. Good 2 , Ashish Jindal 3 , Juan M. Pascual 2,4 , Ralph J. DeBerardinis 1 , Robert M. Bachoo 2 , Elizabeth A. Maher 5 , Craig R. Malloy 3,6 1 Pediatrics, UT Southwestern Medical Center, Dallas, TX, United States; 2 Neurology, UT Southwestern Medical Center, Dallas, TX, United States; 3 Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States; 4 Physiology, UT Southwestern Medical Center, Dallas, TX, United States; 5 Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States; 6 Radiology, UT Southwestern Medical Center, Dallas, TX, United States 2297. ASL-MRI Measurement of Cerebral Blood Flow Following Experimental Traumatic Brain Injury & the Role of Human Aβ Lesley M. Foley 1 , Eric E. Abrahamson 2 , T. Kevin Hitchens 1,3 , Chien Ho 1,3 , William R. Paljug 2 , John A. Melick 4 , Patrick M. Kochanek 4,5 , Milos D. Ikonomovic 2 1 Pittsburgh NMR Center for Biomedical Research, Carnegie Mellon University, Pittsburgh, PA, United States; 2 Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States; 3 Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, United States; 4 Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States; 5 Departments of Critical Care Medicine, Pediatrics & Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States 2298. Increased Cerebrovascular Complications of Diabetic Mice-A Magnetic Resonance Imaging Study Qiang Shen 1,2 , Eric Muir 1 , Edward S. Hui 1 , Rene C. Rentería 3 , Timothy Q. Duong 1,2 1 Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States; 2 Ophthalmology/Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States; 3 Department of Physiology & Center for Biomedical Neuroscience, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States 2299. Resting-State fMRI & Pharmacological MRI of Changing Dopaminergic Activity in the Developing Rat Brain Kajo van Der Marel 1 , Liesbeth Reneman 2 , Rick M. Dijkhuizen 1
Poster <strong>Session</strong>s 1 2 Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands; Department of Radiology, Academical Medical Center, Amsterdam, Netherlands 2300. In Vivo Characterization of Developing Rabbit Brain with Diffusion Tensor MRI & Tractography Yi-Wen Peng 1 , Yong-Jheng Wun 2 , Cheng-Hung Lai 1 , Jun-Cheng Weng 2,3 1 Department of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan; 2 School of Medical Imaging & Radiological Sciences, Chung Shan Medical University, Taichung, Taiwan; 3 Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung, Taiwan 2301. Diffusion Tensor Imaging for Evaluation of Radiation-Induced Developmental Abnormalities in the White Matter Shigeyoshi Saito 1 , Tsuneo Saga 1 , Ichio Aoki 1 1 Molecular Imaging Center (MIC), National Institute of Radiological Sciences (NIRS), Chiba, Japan 2302. Diffusion Abnormality in Olfactory Bulbs of Type-I Diabetic Rats Li feng Gao 1 , Ming Ming Huang 1 , Hao Lei 1 1 State Key Laboratory of Magnetic Resonance & Atomic & Molecular Physics, Wuhan Institute of Physics & Mathematics, the Chinese Academy of Science, Wuhan, China, People's Republic of 2303. Monitoring Myelination by Transplanted Oligodendrocyte Precursors in Dysmyelinated Mice with MT & DT Imaging Piotr Walczak 1,2 , Jiangyang Zhang 1 , Galit Pelled 1,3 , Segun Bernard 1,2 , Shashikala Galpoththawela 1,2 , James T. Campanelli 4 , Jeff W. M. Bulte 1,2 1 Russel H. Morgan Department of Radiology & Radiological Science, Division of MR Research, Johns Hopkins University, Baltimore, MD, United States; 2 Cellular Imaging Section & Vascular Biology Program, Institute for Cell Engineering, Johns Hopkins University, Baltimore, MD, United States; 3 F. M. Kirby Research Center for Functional Brain Imaging , Kennedy Krieger Institute, Baltimore, MD, United States; 4 Q Therapeutics, Inc., Salt Lake City, UT, United States 2304. Mouse Embryo Phenotyping with Contrast-Enhanced Micro-Diffusion Tensor Imaging Bernard M. Siow* 1,2 , Jon O. Cleary* 1,3 , Nicholas D. Greene 4 , Pankaj Daga 3 , Marc Modat 2 , Roger J. Ordidge 3 , Sebastien Ourselin 2 , Daniel Alexander 2 , Mark F. Lythgoe 1 1 Centre for Advanced Biomedical Imaging, Department of Medicine and Institute of Child Health, UCL, London, United Kingdom; 2 Centre for Medical Image Computing, UCL, London, United Kingdom; 3 Department of Medical Physics and Bioengineering, UCL, London, United Kingdom; 4 Neural Development Unit, Institute of Child Health, UCL, London, * Equal Contribution 2305. Using Structural MRI & DTI to Map Plastic Changes in the Mouse Brain Resulting from Deep Brain Stimulation M. Mallar Chakravarty 1 , 2 , Clement Hamani 3 , 4 , Jacob Ellegood 1 , Mustansir Diwan 3 , Christine Laliberté 1 , Jonathon Bishop 1 , Jun Dazai 1 , Brian J Nieman 1 , Jose N Nobrega 3 , R Mark Henkelman 1 , Jason P Lerch 1 1 Mouse Imaging Centre (MICe), the Hospital for Sick Children, Toronto, Ontario, Canada; 2 Rotman Research Institute, Baycrest, Toronto, Ontario, Canada; 3 Neuroimaging Research Section, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; 4 Division of Neurosurgery, Toronto Western Hospital, Toronto, Ontario, Canada 2306. Bilateral Enucleation Before & After the Critical Period for the Specification of Interhemispheric Axonal Connectivity Induces Similar Changes on White Matter Fractional Anisotropy Christopher D. Kroenke 1 , Jaime F. Olavarria 2 , Andrew S. Bock 2 , Erin N. Taber 1 , Byung Park 1 1 Oregon Health & Science University, Portland, OR, United States; 2 University of Washington, Seattle, WA, United States 2307. Superoxide Dismutase Overexpression Improves FA & ADC in the Brains of a Mouse Model of Alzheimer's Disease Brittany R. Bitner 1,2 , Taeko Inoue 1 , Lingyun Hu 1 , Chi An Chiang 3 , Robia G. Pautler 1,2 1 Molecular Physiology & Biophysics, Baylor College of Medicine, Houston, TX, United States; 2 Translational Biology & Molecular Medicine, Baylor College of Medicine, Houston, TX, United States; 3 Neuroscience, Baylor College of Medicine 2308. In-Vivo Mouse Brain DT-MRI: Assessment of Gender Specific Response to the Thyroid Hormone Remyelinating Treatment Laura-Adela Harsan 1 , Alexandru Parlog 1 , Neele Hübner 1 , Jürgen Hennig 1 , Dominik von Elverfeldt 1 1 Department of Radiology, Medical Physics, University Hospital Center, Freiburg, Germany 2309. Correlation between DTI & Visual Evoked Potential in Mice with Optic Neuritis Dan Xu 1 , Hsiao-Fang Liang 2 , Wei-Xing Shi, Shu-Wei Sun 3 1 Pharmaceutical Sciences & Basic Sciences, Schools of Pharmacy & Medicine, Loma Linda University, Loma Linda, CA, United States; 2 Biophysics & Bioengineering, Loma Linda University; 3 Biophysics & Bioengineering, Loma Linda University, Loma Linda, CA, United States 2310. α7 Nicotinic Receptor Mediation of CNS Inflammatory Response Examined by Magnetic Resonance Imaging & Bioluminescence Imaging 251
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