Poster <strong>Session</strong>s Exhibition Hall Tuesday 13:30-15:30 Computer 93 13:30 4078. Whole Brain 3D Spiral Imaging for Multi-Component T 2 Relaxometry of Multiple Sclerosis in 10 Minutes: A Feasibility Study at 3 Tesla Thanh D. Nguyen 1 , Cynthia Wisnieff 2 , Joseph Comunale 1 , Mitchell Cooper 2 , Dushyant Kumar 1 , Ashish Raj 1 , Martin R. Prince 1 , Yi Wang 1 , Tim Vartanian 3 , Susan A. Gauthier 3 1 Radiology, Weill Cornell Medical College, New York, NY, United States; 2 Biomedical Engineering, Cornell University, Ithaca, NY, United States; 3 Neurology, Weill Cornell Medical College, New York, NY, United States 14:00 4079. FLAIR-SWI: A Combination of 3 Tesla FLAIR & 7 Tesla SWI Phase for Multiple Sclerosis Research Günther Grabner 1,2 , Assunta Dal-Bianco 3 , Melanie Schernthaner 1 , Karl Vass 3 , Hans Lassmann 4 , Siegfried Trattnig 1,2 1 Department of Radiology, Medical University of Vienna, Vienna, Austria; 2 MR Centre of Excellence, Medical University of Vienna, Vienna, Austria; 3 Department of Neurology, Medical University of Vienna, Vienna, Austria; 4 Center for Brain Research, Medical University of Vienna, Vienna, Austria 14:30 4080. Regional Gray & White Matter Atrophy are Largely Unrelated in Relapsing Remitting Multiple Sclerosis Elisabetta Pagani 1 , Maria Assunta Rocca 1,2 , Gianna Riccitelli 1 , Vittorio Martinelli 2 , Marta Radaelli 2 , Andrea Falini 3 , Giancarlo Comi 2 , Massimo Filippi 1,2 1 Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, Scientific Institute & University Hospital San Raffaele, Milan, MI, Italy; 2 Department of Neurology, Scientific Institute & University Hospital San Raffaele, Milan, MI, Italy; 3 Department of Neuroradiology, Scientific Institute & University Hospital San Raffaele, Milan, Italy 15:00 4081. Similar Global N-Acetylaspartate in Benign & Non-Benign Multiple Sclerosis Daniel J. Rigotti 1 , Lutz Achtnichts 2 , Oded Gonen 1 , James S. Babb 1 , Yvonne Naegelin 2 , Kerstin Bendtfield 2 , Jochen Hirsch 2 , Michael Amann 2 , Robert I. Grossman 1 , Ludwig Kapposs 2 , Achim Gass 2 1 2 Radiology, New York University School of Medicine, New York, NY, United States; Neurology & Neuroradiology, University Hospital Basel, Basel, Switzerland Exhibition Hall Wednesday 13:30-15:30 Computer 93 13:30 4082. Normalization of Magnetization Transfer Ratio MRI for Multicentre Clinical Trials Robert Allan Brown 1 , Sridar Narayanan 1 , Harold Atkins 2 , Mark S. Freedman 3 , Douglas L. Arnold 1 1 Montreal Neurological Institute, McGill University, Montreal, QC, Canada; 2 Division of Hematology, Ottawa Hospital Regional Cancer Centre, Ottawa, ON, Canada; 3 Department of Medicine (Neurology), the Ottawa Hospital, Ottawa, ON, Canada 14:00 4083. Sensitive Detection of Myelination Change in Multiple Sclerosis by McDESPOT Jason Su 1 , Hagen H. Kitzler 2 , Michael Zeineh 1 , Cyndi Harper-Little 3 , Andy Leung 4 , Marcelo Kremenchutzky 5 , Sean C. Deoni 6 , Brian Keith Rutt 1 1 Department of Radiology, Stanford University, Stanford, CA, United States; 2 Department of Neuroradiology, Technische Universitaet Dresden, Dresden, Germany; 3 Robarts Research Institute, University of Western Ontario, London, Ontario, Canada; 4 Department of Diagnostic Radiology & Nuclear Medicine, University of Western Ontario, London, Ontario, Canada; 5 Department of Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada; 6 Brown University, Providence, RI, United States 14:30 4084. A New Quantitative MRI Contrast for Measuring White Matter Myelin Aviv A. Mezer 1 , Nikola Stikov 2 , Kendrick Kay, Robert Dougherty, Jason Yeatman, Josef Parvizi 3 , Brian Wandell 1 Psychology, Stanford University, Stanford, CA, United States; 2 Electrical Engineering, Stanford University, Stanford, CA, United States; 3 Neurology, Stanford University, Stanford, CA, United States 15:00 4085. Voxel-Wise Assessment of WM Architecture Integrity in MS Patients with Different Clinical Phenotypes Elisabetta Pagani 1 , Maria Assunta Rocca 1,2 , Gianna Riccitelli 1 , Vittorio Martinelli 2 , Filippo Martinelli-Boneschi 2 , Andrea Falini 3 , Giancarlo Comi 2 , Massimo Filippi 1,2 1 Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, Scientific Institute & University Hospital San Raffaele, Milan, Italy; 2 Department of Neurology, Scientific Institute & University Hospital San Raffaele, Milan, Italy; 3 Department of Neuroradiology, Scientific Institute & University Hospital San Raffaele, Milan, Italy Exhibition Hall Thursday 13:30-15:30 Computer 93 13:30 4086. Brain Atlas-Based Lesion Spatial Distribution & Modeling of Wallerian Degeneration in Multiple Sclerosis Khader M. Hasan 1 , Indika S. Walimuni 1 , Sushmita Datta 1 , Flavia Nelson 2 , Jerry S. Wolinsky 3 , Ponnada A. Narayana 4 1 Radiology, UTHSCH, Houston, TX, United States; 2 Neurology, UTHSCH, Houston, TX; 3 Neurology, UTHSCH, Houston, Texasa, United States; 4 Radiology, UTHSCH, Houston, Uexasa, United States 424
Poster <strong>Session</strong>s 14:00 4087. Voxel-Wise Assessment of White Matter Architecture Integrity in Patients with Relapsing Remitting Multiple Sclerosis Gianna Riccitelli 1 , Maria Assunta Rocca 1,2 , Elisabetta Pagani 1 , Vittorio Martinelli 2 , Paolo Rossi 2 , Andrea Falini 3 , Giancarlo Comi 2 , Massimo Filippi 1,2 1 Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, Scientific Institute & University Hospital San Raffaele, Milan, MI, Italy; 2 Department of Neurology, Scientific Institute & University Hospital San Raffaele, Milan, MI, Italy; 3 Department of Neuroradiology, Scientific Institute & University Hospital San Raffaele, Milan, Italy 14:30 4088. FLAIR MIPS: Increased White Matter Lesion Conspicuity Kenneth L. Weiss 1 , Virginia B. Hill 2 , Kenneth J. Herbert 1 , Senthur J Thangasamy 1 , Yichun Lin 3 , Jun Ying 4 , Jane L. Weiss 5 , Maria J. Melanson 6 1 Department of Radiology, University of Cincinnati, Cincinnati, OH, United States; 2 Department of Radiology, Cleveland Clinic Regional Radiology, Cleveland, OH, United States; 3 College of Medicine, Cincinnati, OH, United States; 4 Department of Public Health Science, University of Cincinnati, Cincinnati, OH, United States; 5 Division of Research, WestImage, Cincinnati, OH, United States; 6 Department of Neurology, University of Cincinnati, Cincinnati, OH, United States 15:00 4089. Is Increased Normal White Matter Glutamate Concentrations a Precursor of Gliosis & Disease Progression in Multiple Sclerosis? Olof Dahlqvist Leinhard 1,2 , Jacek Jaworski 3 , Anne Aalto 4 , Anders Grönqvist 5 , Anders Tisell 1,2 , Örjan Smedby 2,4 , Anne- Marie Landtblom 3,6 , Peter Lundberg 5,7 1 Dept of Radiation physics (IMH), Linköping University, Linköping, Sweden; 2 Center for Medical Image Science & Visualization (CMIV), Linköping University, Linköping, Sweden; 3 Department of Neurology, Linköping University Hospital, Linköping, Sweden; 4 Dept of Radiology (IMH), Linköping University, Linköping, Sweden; 5 Dept of Radiation Physics (CKOC), Linköping University Hospital, Linköping, Sweden; 6 Division of Clinical Immunology, Unit of Autoimmunity and Immune Regulation (IKE), Linköping University, Linköping, Sweden; 7 Dept of Radiation physics (IMH), Center for Medical Image Science & Visualization (CMIV), Linköping University, Linköping, Sweden White Matter Diseases Exhibition Hall <strong>Monday</strong> 14:00-16:00 Computer 94 14:00 4090. Detecting Histological Changes in Traumatic Brain Injury with Magnetization Transfer Imaging Nikolaus Krebs 1,2 , Michaela Soellinger 3 , Michael Scarpatetti 4 , Christian Langkammer 1,3 , Monika Gloor 5 , Stefan Ropele 3 , Franz Fazekas 3 , Kathrin Yen 1 , Eva Scheurer 1 1 Ludwig Boltzmann Institute for Clinical-Forensic Imaging, Graz, Austria; 2 Institute of Forensic Medicine, Medical University of Graz, Graz, Austria; 3 Department of Neurology, Medical University of Graz, Graz, Austria; 4 Institute of Pathology, Medical University of Graz, Graz, Austria; 5 Division of Radiological Physics, University of Basel Hospital, Basel, Switzerland 14:30 4091. Reduced Callosal Thickness & Volume Due to Myelin Deficit in RLS: Thickness Measurement & Volumetric Study Byeong-Yeul Lee 1,2 , Jong M. Kim 3 , Yeun Chul Ryu 1 , James R. Connor 4 , Qing X. Yang 1,4 1 Center for NMR Research, Radiology, Penn State College of Medicine, Hershey, PA, United States; 2 Bioengineering, Penn State College of Medicine, Hershey, PA, United States; 3 Biomedical Engineering, Duke University, Durham, NC, United States; 4 Neurosurgery, Penn State College of Medicine, Hershey, PA, United States 15:00 4092. MR Spectroscopy of the Motor Cortex in Cervical Spondylotic Myelopathy: Pre & Post Surgery Observations Izabela Kowalczyk 1,2 , Neil Duggal 1,3 , Robert Bartha 1,2 1 Medical Biophysics, the University of Western Ontario, London, Ontario, Canada; 2 Centre for Functional & Metabolite Mapping, Robarts Research Institute, London, Ontario, Canada; 3 Clinical Neurological Sciences, University Hospital, London Health Sciences Centre, London, Ontario, Canada 15:30 4093. Loss of Callosal Fibre Integrity in Healthy Elderly with Small Vessel Disease Martin Griebe 1 , Alex Förster 1 , Michèle Wessa 2 , Christina Rossmanith 1 , Tamara Sauer 1 , Kathrin Zohsel 1 , Andrea V. King 2 , Michael G. Hennerici 1 , Achim Gass 1 , Kristina Szabo 1 1 Department of Neurology, UniversitätsMedizin Mannheim, University of Heidelberg, Mannheim, Germany; 2 Department of Cognitive & Clinical Neuroscience, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany Exhibition Hall Tuesday 13:30-15:30 Computer 94 13:30 4094. Metabolic Characterization of Gray & White Matter in Mild Traumatic Brain Injury with 3D Proton MR Spectroscopy Ivan Kirov 1 , Assaf Tal 1 , James Babb 1 , Joseph Reaume 1 , Robert Grossman 1 , Oded Gonen 1 1 Radiology, New York University, New York, NY, United States 425
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