Tuesday <strong>AM</strong> Bridging the Gap between MR & ER Room 520B-F 10:30-12:30 Moderators: Jalal B. Andre & Daniela Prayer 10:30 Imaging Requirements in the Emergency Room James V. Quinn 11:00 Neurological Emergencies: MR vs CT Nancy J. Fischbein 11:30 From the ER to the MR Suite at a Major Academic Hospital: A Body Imager's Perspective Elmar M. Merkle 12:00 ER: A Challenge for MR Technology Steven M. Conolly Manganese Enhanced MRI - Advances & Applications Room 710A 10:30-12:30 Moderators: Nicholas A. Bock & Daniel H. Turnbull 10:30 234. In Vivo Manganese-Enhanced MRI of Conditioned Fear Response Iris Yuwen Zhou 1,2 , Abby Y. Ding 1,2 , Qi Li 3,4 , Frank Yik Hin Lee 1,2 , Shujuan J. Fan 1,2 , Kevin Chuen Wing Chan 1,2 , Grainne M. McAlonan 3,4 , Ed Xuekui Wu 1,2 1 Laboratory of Biomedical Imaging & Signal Processing, the University of Hong Kong, Hong Kong SAR, China, People's Republic of; 2 Department of Electrical & Electronic Engineering, the University of Hong Kong, Hong Kong SAR, China, People's Republic of; 3 4 Department of Psychiatry, the University of Hong Kong; Centre for Reproduction Growth & Development, the University of Hong Kong 10:42 235. Mapping CNS Response to Leptin by MEMRI A-B-M-A Asad 1 , Serene Y. L. Tong 1 , Ma Wei 2 , Weiping Han 2 , Kai-Hsiang Chuang 1 1 Magnetic Resonance Imaging Group, Singapore Bioimaging Consortium, A*STAR, Singapore, Singapore; 2 Lab of Metabolic Medicine, Singapore Bioimaging Consortium, A*STAR, Singapore, Singapore 10:54 236. Biocompatible & pH Sensitive PLGA Encapsulated Mno Nanocrystals for Molecular & Cellular MRI Margaret F. Bennewitz 1 , Michael K. Nkansah 1 , Tricia L. Lobo 2 , Erik M. Shapiro 1,2 1 Department of Biomedical Engineering, Yale University, New Haven, CT, USA; 2 Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA 11:06 237. In-Vivo Detection of Cell Cycle Arrest using Manganese-Enhanced MRI (MEMRI) Shigeyoshi Saito 1 , Sumitaka Hasegawa 1 , Takako Furukawa 1 , Tsuneo Saga 1 , Ichio Aoki 1 1 Molecular Imaging Center (MIC), National Institute of Radiological Sciences (NIRS), Chiba, Japan 11:18 238. MEMRI Atlas of Neonatal Mouse Brain Development Kamila Urszula Szulc 1 , Brian J. Nieman 2 , Edward Jospeh Houston 1 , Alexandra L. Joyner 3 , Daniel H. Turnbull 1,4 1 Kimmel Center for Biology & Medicine at the Skirball Institute of Biomolecular Medicine, NYU School of Medicine, New York, NY, USA; 2 Mouse Imaging Center, Hospital for Sick Children, Toronto, Canada; 3 Developmental Biology Program, Sloan-Kettering Institute, New York, NY, USA; 4 Radiology, NYU School of Medicine, New York, NY, USA 11:30 239. Brain Regions Showing Manganese Accumulation in the Human versus the Rat Brain Ulrike Dydak 1,2 , Jun Xu 1,2 , Ashritha Epur 2 , Xiangrong Li 3 , Seth Streitmatter 1 , Li-Ling Long 3 , Wei Zheng 1 , Yue-Ming Jiang 4 1 School of Health Sciences, Purdue University, West Lafayette, IN, USA; 2 Department of Radiology & Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA; 3 Department of Radiology, Guangxi Medical University, Nanning, China, People's Republic of; 4 Department of Health Toxicology, Guangxi Medical University, Nanning, China, People's Republic of 11:42 240. Mn Distribution in Rat Hippocampus: Correlative use of Synchrotron X-Ray Microprobe & MEMRI Alexia Daoust 1,2 , Emmanuel Luc Barbier 1,2 , Sylvain Bohic 1,3 1 INSERM U836, Grenoble, France; 2 Grenoble Institut des Neurosciences, Université Joseph Fourier, Grenoble, France; 3 European Synchrotron Radiation Facility (ESRF), Grenoble, France 11:54 241. Detection of Altered Axonal Transport a Mouse Model of Neurofibromatosis using Manganese Enhanced MRI Kevin M. Bennett 1 , Shannon S. Olfers 2 , Vinodh Narayanan 2 1 School of Biological & Health Systems Engineering, Arizona State University, Tempe, Az, USA; 2 Developmental Neurogenetics Laboratory, Barrow Neurological Institute, Phoenix, Az, USA 34
Tuesday <strong>AM</strong> 12:06 242. Aging Impacts Significantly on Neuronal Transport in Normal Mice but Not in an Accelerated Mouse Model of Amyloid Beta Pathology Umer Abdur Rahim Khan 1 , Anne Bertrand 1,2 , Hoang Minh Dung 1 , Dmitry Novikov 1 , Lindsay Kathleen Hill 1 , Benjamin Winthrope Little 1 , Hameetha B. Rajamohamed Sait 3 , Mesha Shamsie 1 , Einar M. Sigurdsson 3 , Youssef Zaim Wadghiri 1 1 Radiology, New York University Langone Medical Center, New York, NY, USA; 2 URA CEA-CNRS 2210, Mircen, Fontenay-Aux- Roses, France; 3 Physiology & Neuroscience, New York University Langone Medical Center, New York, NY, USA 12:18 243. Paraformaldehyde & Glutaraldehyde Fixations Preserve Manganese Enhancement in Ex Vivo Mouse Brain MRI Yutong Liu 1 , Larisa Poluektova 2 , Balasrinivasa Sajja 1 , Howard Gendelman 2 , Boska Michael 1 1 Radiology, UNMC, Omaha, NE, USA; 2 Pharmacology/Exp Neuroscience, UNMC, Omaha, NE, USA Human Brain Tumors: Response to Therapy Room 710B 10:30-12:30 Moderators: Meng Law & Brian D. Ross 10:30 244. Graded Functional Diffusion Maps (Fdms) Predict Survival in Recurrent Glioblastoma Treated with Bevacizumab Benjamin M. Ellingson 1 , Timothy F. Cloughesy 2 , Albert Lai 2 , Phioanh L. Nghiemphu 2 , Whitney B. Pope 1 1 2 Radiological Sciences, University of California Los Angeles, Los Angeles, CA, USA; Neurology, University of California Los Angeles, Los Angeles, CA, USA 10:42 245. Combined 31 P & 1 H MRSI in Recurrent Glioblastomas Prior & Post Antiangiogenetic Therapy Ulrich Pilatus 1 , Oliver Bähr 2 , Joachim Steinbach 2 , Elke Hattingen 1 1 Institute of Neuroradiology, Goethe University Frankfurt, Frankfurt/Main, Germany; 2 Senckenbergisches Institut für Neuroonkologie, Goethe University Frankfurt, Frankfurt/Main, Germany 10:54 246. MR Spectroscopy as a Biomarker to Predict the Responses of Glioblastoma to an Anti-Angiogenic Treatment Heisoog Kim 1 , Ciprian Catana 1 , Eva-Maria Ratai 1 , Ovidiu C. Andronesi 1 , Tracy T. Batchelor 2 , Rakesh K. Jain 3 , A. Gregory Sorensen 1 1 Radiology, A. A. Martinos Center, Charlestown, MA, USA; 2 Neurology, Massachusetts General Hospital, Boston, MA, USA; 3 Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA 11:06 247. Increased Blood Flow during Anti-VEGF Induced Vascular Normalization Kyrre E. Emblem 1 , Pavlina Polaskova 1 , Dominique L. Jennings 1 , Elizabeth R. Gerstner 2 , Tracy T. Batchelor 2 , Rakesh K. Jain 3 , A. Gregory Sorensen 1 1 A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA; 2 Pappas Center for Neuro- Oncology, Massachusetts General Hospital, Boston, MA, USA; 3 Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA 11:18 248. Improved Localization of BOLD Activation in Patients with Brain Tumors using Vasoreactivity Maps Henning U. Voss 1 , Kyung K. Peck 2 , Nicole M. Petrovich Brennan 2 , Amir Iranmahboob 2 , Bob L. Hou 3 , Andrei I. Holodny 2 1 Dept. of Radiology, Weill Cornell Medical College, New York, NY, USA; 2 Dept. of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA; 3 Dept. of Radiology, West Virginia University, Morgantown, VA, USA 11:30 249. Serial Changes in Diffusion Imaging Parameters Vary with Treatment Regimen for Patients with Newly Diagnosed Glioblastoma Multiforme Laleh Jalilian 1 , Emma Essock-Burns 2 , Yan Li 1 , Soonmee Cha 1,3 , Susan Chang 3 , Michael Prados 3 , Nicholas Butowski 3 , Sarah J. Nelson 1,2 1 Radiology & Biomedical Imaging, UCSF, San Francisco, CA, USA; 2 Bioengineering, UCSF, San Francisco, CA, USA; 3 Neurological Surgery, UCSF, San Francisco, CA, USA 11:42 250. How Blood Perfusion Maps are Analyzed Can Greatly Improve the Predictive Potential For Assessing Survival in Patients Treated For Gliomas Benjamin Lemasson 1 , Stefanie Galbán 2 , Christina Tsien 2 , Charles R. Meyer 1,3 , Timothy D. Johnson 4 , Thomas Leonard Chenevert 1 , Alnawaz Rehemtulla 1,2 , Brian Dale Ross 1 , Craig J. Galbán 1 1 Radiology, University of Michigan, Ann Arbor, MI, USA; 2 Radiation Oncology, University of Michigan, Center for Molecular Imaging, Ann Arbor, MI, USA; 3 Biomedical, University of Michigan, Center for Molecular Imaging, Ann Arbor, MI, USA; 4 Biostatistics, University of Michigan, Ann Arbor, MI, USA 35
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