Monday AM 1 Opening Session 2011 Mansfield Lecture ... - ISMRM

Poster Sessions
244
United States; 4 Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, United States; 5 Department of Psychiatry
& Behavioral Medicine, Medical College of Wisconsin, Milwaukee, WI, United States
Animal Models in Neurodegenerative Diseases
Exhibition Hall Tuesday 13:30-15:30
2227. Early Anatomical & Microstructural Changes Induced in Rat Brain by Vitamin a Deprivation: A Longitudinal
MRI Study
Bassem Hiba 1 , Bader Chaarani 1 , M. C. Beauvieux 1 , G. Rafard 1 , Michèle Allard 2 , Alan Stephant 1 , Jean Michel
Franconi 1 , Jean Louis Gallis 1
1 UMR 5536 RMSB, CNRS-UB2, Bordeaux, France; 2 UMR 5231, CNRS-UB2, Bordeaux, France
2228. T 1ρ MRI as a Marker of Neurofibrillary Tangles in a Mouse Model of Alzheimer’s Disease
Rachelle Berger 1 , Matthew Fenty 2 , Michiyo Iba 3 , Virginia M.-Y. Lee 3 , John A. Detre 4 , Ari Borthakur 5
1 Biochemistry & Molecular Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA, United States; 2 CMROI,
Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, PA, United States; 3 CNDR, Department of
Pathology & Lab Medicine, University of Pennsylvania School of Medicine; 4 CfN, Department of Neurology, University of
Pennsylvania School of Medicine; 5 CMROI, Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia,
PA, United States
2229. A Diffusion Kurtosis Imaging (DKI) Based Correlate for Plaque Load in the APPPS 1 Mouse Model for
Alzheimer's Disease (AD)
Greetje Vanhoutte 1 , Sandra Pereson 2 , Bob Asselbergh 2 , Christine Van Broeckhoven 2 , Anne-Marie Van Der Linden 1
1 Biomedical Sciences, Bio-Imaging Lab, University of Antwerp, Antwerp, Belgium; 2 Molecular Genetics, VIB & Institute Born-
Bunge, University of Antwerp, Antwerp, Belgium
2230. Ultra-High Field Magnetic Resonance Microimaging in Zebrafish Model of Cystic Leukoencephalopathy
Alia Alia 1 , Haud Noémie 2 , Firat Kara 1 , Adam Hurlstone 2
1 Leiden Institute of Chemistry, Leiden University, Leiden, South holland, Netherlands; 2 University of Manchester, United Kingdom
2231. Changes in Glucose Level with Age & Its Correlation with Severity of Plaque Deposition in a Transgenic Model
of Alzheimer’s Disease
Firat Kara 1 , Kristin Möbius 1 , Mark A. van Buchem 2 , Huub J. M. de Groot 1 , Reinhard Schliebs 3 , Alia Alia 1,4
1 Leiden Institute of Chemistry, Leiden University, Leiden, South holland, Netherlands; 2 Department of Radiology, Leiden University
Medical Centrum, Leiden, South Holland, Netherlands; 3 Department of Neurochemistry, University of Leipzig, Leipzig, Germany;
4 Department of Radiology, Leiden University Medical Centrum, Leiden, Netherlands
2232. In Vivo Neuronal Transport Impairment Reflects the Level of Abnormal Tau in a Mouse Model of Tauopathy :
A Track-Tracing Memri Study
Anne Bertrand 1,2 , Umer Khan 2 , Dung Minh Hoang 2 , Dmitry Novikov 2 , Pavan Krishnamurthy 3 , Hameetha Banu
Rajamohamed Sait 3 , Benjamin Winthrop Little 2 , Einar M. Sigurdsson 3 , Youssef Zaim Wadghiri 2
1 URA CEA-CNRS 2210, MIRCen, Fontenay-Aux-Roses, France; 2 Radiology, NYULMC, New York, United States; 3 Physiology &
Neuroscience, NYULMC, New York, United States
2233. Detection of Treatment Effects with 1 H MRS in Transgenic Mouse Model of Alzheimer’s Disease
Malgorzata Marjanska 1 , Stephen D. Weigand 2 , Geoffry L. Curran 2 , Thomas M. Wengenack 2 , Joseph F. Poduslo 2 ,
Michael Garwood 1 , Clifford R. Jack, Jr. 2
1 2
Radiology, University of Minnesota, Minneapolis, MN, United States; Mayo Clinic College of Medicine, Rochester, MN, United
States
2234. 3D Quantitative Micro-MRI Mapping of Alzheimer’s Plaques in Transgenic Mice using Aβ1-42 Targeted-
USPIOs
Dung Minh Hoang 1 , Jing Yang 2 , Lindsay K. Hill 1 , Wai Tsui 3 , Yanjie Sun 2 , Yongsheng Li 2 , Mony De Leon 3 , Thomas
Wisniewski 2,3 , Youssef Zaim Wadghiri 1
1 Radiology, NYU School of Medicine, New York, NY, United States; 2 Neurology, NYU School of Medicine, New York, NY, United
States; 3 Psychiatry, NYU School of Medicine, New York, NY, United States
2235. Response to Donepezil Challenge in Rat Brain by RCBV-Based PhMRI
Thomas Kaulisch 1 , Holger Rosenbrock 2 , Detlef Stiller 3
1 In-Vivo Imaging, Target Discovery Research , Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany; 2 CNS Diseases
Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany; 3 In-Vivo Imaging, Target Discovery Research,
Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany