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Monday AM 1 Opening Session 2011 Mansfield Lecture ... - ISMRM

Monday AM 1 Opening Session 2011 Mansfield Lecture ... - ISMRM

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Friday <strong>AM</strong><br />

86<br />

California San Francisco, San Francisco, CA, USA; 5 Department of BioEngineeing & Therapeutic Sciences, Unviersity of California<br />

San Francisco, San Francisco, CA, USA; 6 Department of Neurology, University of California San Francisco, San Francisco, CA, USA<br />

13:50 603. Quantitative Characterization of Cortical Pathology in Multiple Sclerosis using Surface-Based Analysis of T 2*<br />

Relaxation At 7T<br />

Julien Cohen-Adad 1,2 , Karl G. Helmer 1,2 , Allen Scott Nielsen 3 , Doug Greve 1,2 , Thomas Benner 1,2 , Rip Philip Kinkel 2,3 ,<br />

Bruce R. Rosen 1,2 , Caterina Mainero 1,2<br />

1 A. A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA;<br />

2 Harvard Medical School, Boston, MA, USA; 3 Beth Israel Deaconess Medical Center, Boston, MA, USA<br />

14:00 604. Multiple Sclerosis Alters Intra-cellular Sodium Concentration & Intra-cellular Volume Fraction: An In-Vivo 7T<br />

MRI study<br />

Lazar Fleysher 1 , Niels Oesingmann 2 , Ryan Brown 1 , Hina Jaggi 1 , Graham Wiggins 1 , Daniel Sodickson 1 , Joseph<br />

Herbert 3 , Matilde Inglese 1<br />

1 2 3<br />

Radiology, NYU School of Medicine, New York, USA; Siemens Medical Solutions USA, Malvern, PA, USA; Neurology, NYU<br />

School of Medicine, New York, USA<br />

14:10 605. Atlas-Based Quantification of Brain Normal-Appearing White & Gray Matter Volume, Relaxation Time &<br />

Diffusion Tensor Metrics in Multiple Sclerosis<br />

Khader M. Hasan 1 , Indika S. Walimuni 1 , Sushmita Datta 1 , Flavia Nelson 2 , Jerry S. Wolinsky 3 , Ponnada A. Narayana 4<br />

1 Radiology, UTHSCH, Houston, TX, USA; 2 Neurology, UTHSCH, Houston, TX; 3 Neurology, UTHSCH, Houston, Texasa, USA;<br />

4 Radiology, UTHSCH, Houston, Uexasa, USA<br />

14:20 606. Ten-Year Brain Atrophy Rate & Its Relevance to Disability in Multiple Sclerosis<br />

Antonio Giorgio 1 , Maria Laura Stromillo 1 , Maria Letizia Bartolozzi 2 , Francesca Rossi 3 , Marco Battaglini 3 , Anita<br />

Blandino 3 , Leonello Guidi 2 , Patrizia Maritato 2 , Antonio Federico 3 , Nicola De Stefano 3<br />

1 Department of Neurological & Behavioral Sciences , University of Siena, Siena, Italy; 2 Neurology Unit, Hospital of Empoli, Italy;<br />

3 Department of Neurological & Behavioral Sciences, University of Siena, Siena, Italy<br />

14:30 607. Reversible NAA Decreases in Active MS Lesions Are Not Due Solely to Water Content Changes<br />

Irene Vavasour 1 , Cornelia Laule 1,2 , Madeleine Hodgson 3 , David Li 1 , Anthony Traboulsee 4 , Burkhard Maedler 5 ,<br />

Alexander MacKay 1,3<br />

1 Radiology, University of British Columbia, Vancouver, British Columbia, Canada; 2 Pathology & Laboratory Medicine, University of<br />

British Columbia, Vancouver, British Columbia, Canada; 3 Physics & Astronomy, University of British Columbia, Vancouver, British<br />

Columbia, Canada; 4 Medicine (Neurology), University of British Columbia, Vancouver, British Columbia, Canada; 5 Neurosurgery,<br />

University of Bonn, Germany<br />

14:40 608. Quantitative Assessment of Iron in Multiple Sclerosis Lesions<br />

Christian Langkammer 1 , Michael Khalil 1 , Christian Enzinger 1 , Mirja Wallner-Blazek 1 , Margit Jehna 1 , Siegried Fuchs 1 ,<br />

Franz Fazekas 1 , Stefan Ropele 1<br />

1 Department of Neurology, Medical University of Graz, Graz, Austria<br />

14:50 609. Longitudinal Tract-Based Spatial Statistics Analysis Reveals Left & Right Asymmetric DTI Alterations in<br />

Relapsing Remitting Multiple Sclerosis<br />

Salem Hannoun 1 , Francoise Durand-Dubief 1,2 , Christian Confavreux 2 , Francois Cotton 1 , Dominique Sappey-<br />

Marinier 1,3<br />

1 CREATIS, University of Lyon, Lyon, Rhone-Alpes, France; 2 Neurological Hospital, Lyon, Rhone-Alpes, France; 3 CERMEP-<br />

Imagerie du Vivant, Lyon, Rhone-Alpes, France<br />

15:00 610. Axonal Damage in the Making: Neurofilament Phosphorylation & Magnetization Transfer in MS Non-Lesional<br />

White Matter<br />

Klaus Schmierer 1,2 , Dan Tozer 2 , Axel Petzold 2,3<br />

1 Barts and the London School of Medicine & Dentistry, London, England, United Kingdom; 2 Neuroinflammation, UCL Institute of<br />

Neurology, London, United Kingdom; 3 Free University Medical Centre, Amsterdam, Netherlands

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