Poster <strong>Session</strong>s 168 Donghoon Lee 1 , Kenneth Marro 1 , Mark Mathis 1 , Eric Shankland 1 , Cecil Hayes 1 1 University of Washington, Seattle, WA, United States 1396. Multi-Variate Pattern Analysis for Identification of Metabolites that are Predictive of Malignant Transformation in Gliomas using HRMAS Spectra from Image Guided Tissue Samples Alexandra Constantin 1 , Adam Elkhaled 2 , Trey Jalbert 2 , Radhika Srinivasan 2 , Soonmee Cha 3 , Susan M. Chang 3 , Ruzena Bajcsy 1 , Sarah J. Nelson 2 1 Electrical Engineering & Computer Science, University of California, Berkeley, CA, United States; 2 Department of Radiology & Biomedical Imaging, University of California, San Francisco, CA, United States; 3 Department of Neurological Surgery, University of California, San Franisco, CA, United States 1397. Ex Vivo Ischemic Kidney Damage 23 Na Relaxometry Christoffer Laustsen 1,2 , Steffen Ringaard 1 , Mads Damkjær 3 , Michael Pedersen 1 1 Klinisk Institut, The MR Research Centre, Aarhus University, Aarhus, Denmark; 2 Danish Research Centre for Magnetic Resonance, Hvidovre Hospital, Hvidovre, Denmark; 3 Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark 1398. Improved Data Analysis for Two-Dimensional J-Resolved 1 H-MRS: Application in Brain Tumors Changho Choi 1 , Sandeep Ganji 1 , Elizabeth Maher 2 1 Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States; 2 Internal Medicine & Neuro-oncology, University of Texas Southwestern Medical Center, Dallas, TX, United States 1399. GABA Fitting for MEGA-PRESS Sequences with Different Selective Inversion Frequencies Zaiyang Long 1,2 , James Brown Murdoch 3 , Jun Xu 1,2 , Ulrike Dydak 1,2 1 School of Health Sciences, Purdue University, West Lafayette, IN, United States; 2 Department of Radiology & Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States; 3 Toshiba Medical Research Institute USA, Mayfield Village, OH, United States 1400. Simple Implementation of an Inductively Coupled Synthetic Signal Injection Method on a Clinical MR Scanner for Absolute Quantification Donghoon Lee 1 , Kenneth Marro 1 , Eric Shankland 1 , Mark Mathis 1 , Timothy Wilbur 1 , Gregory Wilson 1,2 , Jeff Stevenson 1 , Cecil Hayes 1 , Kenneth Maravilla 1 1 University of Washington, Seattle, WA, United States; 2 MR Clinical Science, Philips Healthcare, Cleveland, OH, United States 1401. Synthetic Signal Injection using a Single RF Channel Kenneth I. Marro 1 , Donghoon Lee 1 , Eric G. Shankland 1 , C. Mark Mathis 1 , Cecil E. Hayes 1 1 Radiology, University of Washington, Seattle, WA, United States 1402. Quantitative Measurement of N-Acetylaspartyl Glutamate (NAAG) at 3 Tesla using TE-Averaged PRESS Spectroscopy & Lineshape Deconvolution Yan Zhang 1 , Shizhe Li 1 , Christine Rebsch 1 , Stefano Marenco 1 , Jun Shen 1 1 National Institute of Mental Health, Bethesda, MD, United States 1403. A Multi-Purpose Simulator of Coupled Spin Systems for MR Localized Spectroscopy & Spectroscopic Imaging Zenon Starcuk Jr. 1 , Jana Starcukova 1 , Danielle Graveron-Demilly 2 1 Magnetic Resonance & Bioinformatics, Institute of Scientific Instruments, Academy of Sciences of the Czech Republic, Brno, Czech Republic; 2 Creatis-LRMN, Université Claude Bernard Lyon 1, France 1404. The Classification of In Vivo Proton Magnetic Resonance Spectroscopy of Brain Abscesses using Principal Component Analysis (PCA) Ssu-Ying Lu 1 , Cheng-Wen Ko, Tzu-Chao Chuang, Ping-Hong Lai 2,3 1 2 3 National Sun Yat-sen University, Kaohsiung, Taiwan; Veterans General Hospital-Kaohsiung; School of Medicine, National Yang- Ming University, Taipei, Taiwan 1405. Quantification of Rat Brain Metabolites by ProFit: Preliminary Evaluation of High Fat Diet Induced Obesity Bhaskaran David Prakash 1 , Arunima Pola 1 , Na Agarwal 1 , Sambasivam S. Velan 1 1 Laboratory of Molecular Imaging, Singapore Bioimaging Consortium, Singapore, Singapore 1406. Experimental Errors as Alternative to the Theoretical Cramér-Rao Minimum Variance Bounds in MRS: ER- ARSOS - Error Estimation by Multiple Quantification of Recombined ARSOS-Filtered Output Signals Johannes Slotboom 1 , Dirk van Ormondt 2 , Olivier Scheidegger 1 , Caspar Brekenfeld 1 , Roland Wiest 1 , Gerhard Schroth 1 , Danielle Graveron-Demilly 3 1 DRNN-DIN/SCAN, University Hospital Berne, Berne, Switzerland; 2 Applied Physics, Delft University of Technology, Delft, Netherlands; 3 Laboratoire Creatis-LRMN, Université Claude Bernard LYON 1, Lyon, France
Poster <strong>Session</strong>s 1407. Cross-Validation of PRESS, MEGA-PRESS Editing & 2D JPRESS for Neurotransmitter & Antioxidant Detection at 3T using the ERETIC Reference Standard Mariska Petra Luttje 1 , Michael Wyss 1,2 , Niklaus Zölch 1,2 , Alexander Fuchs 1 , Richard A. E. Edden 3,4 , Susanne Heinzer 5 , Peter Bösiger 1 , Anke Henning 1 1 2 3 Institute for Biomedical Engineering, University & ETH Zurich, Zurich, Switzerland; Contributed equally; Russell H. Morgan Department of Radiology & Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States; 4 5 F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States; Philips AG, Zurich, Switzerland 1408. Measuring Tissue PH Heterogeneity by 31 P NMR Spectroscopy Norbert W. Lutz 1 , Yann LeFur 1 , Patrick J. Cozzone 1 1 Dept. of Medicine La Timone, Marseille, France 1409. Quantitative In Vivo Magnetic Resonance Spectroscopy using Synthetic Signal Injection Kenneth I. Marro 1 , Donghoon Lee 1 , Eric G. Shankland 1 , C. Mark Mathis 1 , Cecil E. Hayes 1 , Martin J. Kushmerick 1,2 1 2 Radiology, University of Washington, Seattle, WA, United States; Physiology & Biophysics, University of Washington, Seattle, WA, United States 1410. VeSPA: Integrated Applications for RF Pulse Design, Spectral Simulation & MRS Data Analysis Brian J. Soher 1 , Philip Semanchuk 1 , David Todd 2 , Jeffrey Steinberg 1,3 , Karl Young 2 1 Radiology, Duke University Medical Center, Durham, NC, United States; 2 Radiology, Northern California Institute of Research & Education, San Francisco, CA, United States; 3 Singapore Bioimaging Consortium, Agency for Science, Technology & Research 1411. Repeatability of 2D Magnetic Resonance Spectroscopic Imaging Lawrence Kenning 1 , Martin Lowry 1 , David John Manton 1 , Lindsay W. Turnbull 1 1 Centre for MR Investigations, University of Hull, Hull, United Kingdom 1412. New Technique for Metabolite Cycled Non-Water-Suppressed Proton Spectroscopy in the Human Brain at 7T Erin Leigh MacMillan 1 , Roland Kreis 1 , Alex Fuchs 2 , Maarten J. Versluis 3 , Chris Boesch 1 , Peter Boesiger 2 , Anke Henning 2 1 Dept. of Clinical Research, University of Bern, Bern, Switzerland; 2 Institute for Biomedical Engineering, University & ETH Zurich, Zurich, Switzerland; 3 Dept. of Radiology, Leiden University Medical Center, Leiden, Netherlands 1413. Detection Strategies at 7 Tesla using Clinical MRS Pulse Sequences Subechhya Pradhan 1,2 , John C. Gore 2,3 , Kevin W. Waddell 3,4 1 Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, 37232, United States; 2 Department of Physics & Astronomy, Vanderbilt University, Nashville, TN, United States; 3 Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States; 4 Department of Radiology & Radiological Sciences, Vanderbilt University, Nashville, TN, United States Spectroscopy Localization Exhibition Hall Tuesday 13:30-15:30 1414. Hadamard Encoding of 2D-Selective RF Excitations for Simultaneous Acquisition of Multiple, Irregularly Shaped Voxel in MR Spectroscopy Martin G. Busch 1,2 , Jürgen Finsterbusch 1,2 1 Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2 Neuroimage Nord, University Medical Centers Hamburg-Kiel-Lübeck, Hamburg-Kiel-Lübeck, Germany 1415. Segmented 2D-Selective RF Excitations with Weighted Averaging & Flip Angle Adaptation for MR Spectroscopy of Irregularly Shaped Voxel Jürgen Finsterbusch 1,2 , Martin G. Busch 1,2 1 Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2 Neuroimage Nord, University Medical Centers Hamburg-Kiel-Lübeck, Hamburg-Kiel-Lübeck, Germany 1416. Lactate Detection using Double Quantum Coherence Filtering with Spectral-Spatial Refocusing RF Pulses in a PRESS Sequence Haoyang Xing 1,2 , Yi Sui 1 , Qiyong Gong 3 , Xiaohong Joe Zhou 1,4 1 Center for MR Research, University of Illinois Medical Center at Chicago, Chicago, IL, United States; 2 College of Physical Science & Technology, Huaxi MR Research Center, Sichuan University, Chengdu, Sichuan, China, People's Republic of; 3 Huaxi MR Research Center, West China Hospital of Sichuan University, Chengdu, Sichuan, China, People's Republic of; 4 Departments of Radiology, Neurosurgery & Bioengineering, University of Illinois Medical Center at Chicago 1417. Accelerated 1 H-MRSI: Artifact Reduction by Target-Driven Reconstruction Thomas Kirchner 1 , Anke Henning 1 , Klaas Paul Pruessmann 1 , Peter Boesiger 1 169
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