Monday AM 1 Opening Session 2011 Mansfield Lecture ... - ISMRM

Thursday AM
11:06 554. Histological Verification of Oxygen-Enhanced MRI for Detection of Hypoxia
Inna V. Linnik 1,2 , Marietta Scott 3 , Neil Woodhouse 4 , John C. Waterton 3,5 , Helen Young 3 , Carsten Liess 3 , Hervé Barjat 3 ,
Jose Ulloa 3 , Cassandra L. Hodgkinson 6 , Timothy Ward 6 , Caroline Dive 6 , Darren Roberts 6 , Josephine H. Naish 1,7 ,
Geoffrey J. M. Parker 5,8
1 Imaging Science & Biomedical Engineering, School of Cancer & Enabling Sciences, University of Manchester, Oxford Road,
Manchester M13 9PT, United Kingdom; 2 Biomedical Imaging Institute, University of Manchester, Oxford Road, Manchester M13
9PT, United Kingdom; 3 Imaging, Translational Sciences, AstraZeneca, Alderley Park, Macclesfield, Cheshire, SK10 4TG, United
Kingdom; 4 Imaging, Translational Sciences, AstraZeneca, Alderley Park, Macclesfield, Cheshire, SK10 4TG , United Kingdom;
5 Imaging Science & Biomedical Engineering, School of Cancer & Enabling Sciences, University of Manchester, Oxford Road,
Manchester M13 9PT, United Kingdom; 6 Paterson Institute for Cancer Research, Manchester, United Kingdom; 7 Biomedical Imaging
Institute, University of Manchester, Oxford Road, Manchester M13 9PT, United Kingdom; 8 Biomedical Imaging Institute , University
of Manchester, Oxford Road, Manchester M13 9PT, United Kingdom
11:18 555. In Vivo Dynamic Contrast Enhanced MRI & Histopathological Assessment of Tumor Angiogenesis in Luminal-
Like & Basal-Like Breast Cancer Xenografts
Else Marie Huuse 1 , Siver Andre Moestue 1 , Tone Frost Bathen 1 , Anna Bofin 2 , Gunhild Mari Mælandsmo 3 , Lars A.
Akslen 4 , Olav Engebraaten 3,5 , Ingrid S. Gribbestad 1
1 Department of Circulation & Medical Imaging, Norwegian University of Science & Tehcnology (NTNU), Trondheim, Norway;
2 Department of Laboratory Medicine, Children's & Women's Health, NTNU, Trondheim, Norway; 3 Department of Oncology &
Department of Tumor Biology, Oslo University Hospital, Oslo, Norway; 4 The Gade Institute, Section for Pathology, University of
Bergen, Bergen, Norway; 5 Institute for Clinical Medicine, University of Oslo, Oslo, Norway
11:30 556. Dual PI3K/mTOR Inhibition Induces Structural Changes in Tumor Vasculature Assessed by Vessel Size
Imaging
Shelby Katherine Wyatt 1 , Sharon E. Ungersma 1 , Jason R. Oeh 2 , Calvin Ho 1 , Tim C. Cao 1 , Hartmut Koeppen 3 , Lori S.
Friedman 2 , Deepak Sampath 2 , Richard A. D. Carano 1
1 Biomedical Imaging, Genentech, Inc, South San Francisco, CA, USA; 2 Translational Oncology, Genentech, Inc, South San
Francisco, CA, USA; 3 Pathology, Genentech, Inc, South San Francisco, CA, USA
11:42 557. Genetic Manipulation of Proton Transport Mechanisms Generates Modulations of Intra & Extracellular Ph &
Growth Characteristics in Tumors
Norbert W. Lutz 1 , Johanna Chiche 2 , Yann LeFur 1 , Frederic Frassineti 3 , Laurent Daniel 3 , Jacques Pouyssegur 2 , Patrick
J. Cozzone 1
1 Dept. of Medicine La Timone, Marseille, France; 2 Institute of Developmental Biology & Cancer, University of Nice, Nice, France;
3 Dept. of Pathology La Timone, Marseille, France
11:54 558. Metabolic Profiling of Primary & Recurrent Mammary Gland Tumors in an Inducible Her2/neu Breast Cancer
Mouse Model using 1 H MRS
Dania Daye 1 , James Alvarez 2,3 , Suzanne Wehrli 4 , Mitchell Schnall 5 , Lewis Chodosh 2,3
1 Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA; 2 Department of Cancer Biology, University of
Pennsylvania; 3 Abramson Family Cancer Research Institute, University of Pennsylvania; 4 Nuclear Magnetic Resonance Core Facility,
Children's Hospital of Philadelphia; 5 Department of Radiology, University of Pennsylvania
12:06 559. MRI & MRS Characterization of Two Experimental Models of Ovarian Cancer with Different Glycolytic
Phenotypes
Rossella Canese 1 , Giorgia Nardo 2 , Marika Crescenzi 2 , Egidio Iorio 1 , Stefano Indraccolo 2
1 Istituto Superiore di Sanità, Rome, RM, Italy; 2 Istituto Oncologico Veneto -IRCCS, Padova, Italy
12:18 560. Magnetic Resonance Spectroscopic Imaging of Orthotopic Ovarian Cancer
Marie-France Penet 1 , Kristine Glunde 1 , Dmitri Artemov 1 , Franca Podo 2 , Zaver M. Bhujwalla 1
1 JHU ICMIC Program, Russell H. Morgan Department of Radiology & Radiological Science, The Johns Hopkins University School
of Medicine, Baltimore, MD, USA; 2 Department of Cell Biology & Neurosciences, Section of Molecular & Cellular Imaging, Istituto
Superiore di Sanità, Rome, Italy
The Short of It
Room 520B-F 10:30-12:30 Moderators: Garry E. Gold & Matthew F. Koff
10:30 561. Introduction
Won C. Bae
10:42 562. Clinical Ultra-Short TE-Enhanced T2* Mapping of Meniscus
Ashley Williams 1 , Yongxian Qian 2 , Constance R. Chu 1
1 Cartilage Restoration Center, University of Pittsburgh, Pittsburgh, PA, USA; 2 Department of Radiology, University of Pittsburgh
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