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Monday AM 1 Opening Session 2011 Mansfield Lecture ... - ISMRM

Monday AM 1 Opening Session 2011 Mansfield Lecture ... - ISMRM

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Poster <strong>Session</strong>s<br />

126<br />

958. MRI-Guided Electrochemotherapy (ECT) in a Rat Model of Hepatocellular Carcinoma<br />

Yang Guo 1 , Yue Zhang 2,3 , Ning Jin 2,4 , Jodi Nicolai 2 , Rachel Klein 2 , Guang-Yu Yang 5 , Reed Omary 2,4 , Andrew Larson 2,4<br />

1 Radiology, Northwestern University, Chicago, IL, United States; 2 Department of Radiology, Northwestern University, Chicago, IL,<br />

United States; 3 Biomedical Engineering , University of Illinois at Chicago, Chicago, IL, United States; 4 Department of Biomedical<br />

Engineering , Northwestern University, Chicago, IL, United States; 5 Department of Pathology, Northwestern University, Chicago, IL,<br />

United States<br />

959. Characterizing Breast Tumor Lipid Metabolism by Integrating Magnetic Resonance Spectroscopic Imaging<br />

with MALDI Mass Spectrometric Imaging<br />

Lu Jiang 1 , Kamila Chughtai 2 , Dmitri Artemov 1 , Paul Winnard Jr. 1 , Venu Raman 1 , Zaver Bhujwalla 1 , Ron Heeren 2 ,<br />

Kristine Glunde 1<br />

1 ICMIC, Russell H. Morgan Department of Radiology & Radiological Science, Johns Hopkins Medical School, Baltimore, MD,<br />

United States; 2 FOM-Institute for Atomic & Molecular Physics, Amsterdam, Netherlands<br />

960. Trifluoromisonidazole Detects Hypoxia - An In Vivo & In Vitro Multimodality Study<br />

Ellen Ackerstaff 1 , Makiko Suehiro 1 , Natalia Kruchevsky 1 , Sean Carlin 1 , Eric H. Rosenfeld 1 , Paul Burgman 1 , Guangbin<br />

Yang 1 , Geralda Torchon 1 , Ouathek Ouerfelli 1 , Pat B. Zanzonico 1 , Kristen L. Zakian 1 , Clifton C. Ling 1 , Jason A.<br />

Koutcher 1<br />

1 Memorial Sloan-Kettering Cancer Center, New York, NY, United States<br />

961. Chronic Administration of MRSI Agent IEPA Increases Tumor PH; Has Potential to Bias PH Measurement<br />

Heather H. Cornnell 1 , Ihor Luhach 1 , Gary Martinez 1 , Arig Ibrahim Hashim 1 , Robert A. Gatenby 2 , Robert J. Gillies 1<br />

1 Department of Imaging, Moffitt Cancer Center & Research Instutite, Tampa, FL, United States; 2 Department of Radiology, Moffitt<br />

Cancer Center & Research Instutite, Tampa, FL, United States<br />

962. Assessment of Tumour Glucose Uptake using Gluco-CEST<br />

Simon Walker-Samuel 1 , Peter Johnson 2 , Barbara Pedley 2 , Mark F. Lythgoe* 1 , Xavier Golay* 3<br />

1 UCL Centre for Advanced Biomedical Imaging, Department of Medicine & Institute of Child Health, University College London,<br />

London, United Kingdom; 2 Institute of Cancer, University College London, United Kingdom; 3 Institute of Neurology, University<br />

College London, United Kingdom<br />

963. Localized Hypoxia Results in Spatially Heterogeneous Metabolic Signatures in Breast Tumor Models<br />

Lu Jiang 1 , Dmitri Artemov 1 , Paul Winnard Jr. 1 , Venu Raman 1 , Zaver Bhujwalla 1 , Kristine Glunde 1<br />

1<br />

ICMIC, Russell H. Morgan Department of Radiology & Radiological Science, Johns Hopkins Medical School, Baltimore, MD,<br />

United States<br />

964. Metabolic Characterization of the Cachectic Phenotype<br />

Marie-France Penet 1 , Paul T. Winnard Jr. 1 , Radharani Marik 1 , Sridhar Nimmagadda 1 , Martin G. Pomper 1 , Zaver M.<br />

Bhujwalla 1<br />

1<br />

JHU ICMIC Program, Russell H. Morgan Department of Radiology & Radiological Science, The Johns Hopkins University School<br />

of Medicine, Baltimore, MD, United States<br />

965. In Vivo Magnetic Resonance Studies of Glycine Metabolism & Glutathione Distribution in a Rat Mammary<br />

Tumour<br />

Peter Edward Thelwall 1 , Nicholas E. Simpson 2 , Zahid N. Rabbani 3 , Daniel Clark 2 , Roxana Pourdeyhimi 4 , Jeffrey M.<br />

Macdonald 4 , Stephen J. Blackband 2 , Michael P. Gamcsik 4<br />

1 Newcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, Tyne & Wear, United Kingdom; 2 University of<br />

Florida, United States; 3 Duke University Medical Centre, United States; 4 University of North Carolina / NC State University, United<br />

States<br />

966. Characterization of Macromolecular Transport in Hypoxic Tumor Environments with Disrupted Collagen I<br />

Fibers<br />

Samata M. Kakkad 1 , Marie-France Penet 1 , Arvind Pathak 1 , Meiyappan Solaiyappan 1 , Venu Raman 1 , Kristine Glunde 1 ,<br />

Zaver M. Bhujwalla 1<br />

1<br />

JHU ICMIC Program, Russell H. Morgan Department of Radiology & Radiological Science, Johns Hopkins University School of<br />

Medicine, Baltimore, MD, United States<br />

967. Arterial Spin Labeling Perfusion Measurements Reflect Histologic Microvessel Density in an Experimental<br />

Model of Tumor Response & Eventual Resistance to Antiangiogenic Therapy<br />

Xiaoen Wang 1 , Liang Zhang 2 , Michael P. Collins 3 , Brittany Bahamon 3 , Sabina Signoretti 3 , Michael B. Atkins 2 , David<br />

C. Alsop 4 , Rupal S. Bhatt 2<br />

1 Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA, United States; 2 Division of<br />

Hematology-Oncology & Cancer Biology, Beth Israel Deaconess Medical Center, Boston, MA, United States; 3 Department of<br />

Pathology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States; 4 Department of Radiology, Beth<br />

Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States

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