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Monday AM 1 Opening Session 2011 Mansfield Lecture ... - ISMRM

Monday AM 1 Opening Session 2011 Mansfield Lecture ... - ISMRM

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Wednesday PM<br />

17:00 453. Molecular MRI of Liver Fibrosis by Fibrin-Fibronectin Targeted Contrast Agent in an Experimental Mouse<br />

Model<br />

April M. Chow 1,2 , Mingqian Tan 3 , Darwin S. Gao 1,4 , Shu Juan Fan 1,4 , Jerry S. Cheung 1,4 , Kwan Man 5 , Zheng-Rong Lu 3 ,<br />

Ed X. Wu 1,4<br />

1 Laboratory of Biomedical Imaging & Signal Processing, The University of Hong Kong, Pokfulam, Hong Kong SAR, China, People's<br />

Republic of; 2 Medical Physics & Research Department, Hong Kong Sanatorium & Hospital, Happy Valley, Hong Kong SAR, China,<br />

People's Republic of; 3 Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA; 4 Department<br />

of Electrical & Electronic Engineering, The University of Hong Kong, Pokfulam, Hong Kong SAR, China, People's Republic of;<br />

5 Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong SAR, China, People's Republic of<br />

17:12 454. In Vivo Dynamic Contrast Enhanced MRI of Novel Contrast Agents Targeted to the Estrogen Receptor<br />

Adi Pais 1 , Gunanathan Chidambaram 2 , Inbal Biton 3 , Raanan Margalit 1 , David Milstein 2 , Hadassa Degani 1<br />

1 Biological Regulation, Weizmann Institute of Science, Rehovot, Israel; 2 Organic Chemistry, Weizmann Institute of Science, Rehovot,<br />

Israel; 3 Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel<br />

17:24 455. MRI with Magnetic Nanoparticles Serves As a Biomarker For the Inflammation Associated with the Early,<br />

Insulitic Phase of Type I Diabetes<br />

Alexander R. Guimaraes 1,2 , Jason L. Gaglia 3,4 , Mukesh G. Harisinghani 2 , Christophe Benoist 3,4 , Diane Mathis 3,4 , Ralph<br />

Weissleder 1<br />

1 Center for Systems Biology, Boston, MA, USA; 2 Radiology/Massachusetts General Hospital, Division of Abdominal Imaging &<br />

Interventional Radiology, Boston, MA, USA; 3 Pathology, Harvard Medical School, Boston, MA, USA; 4 Section on Immunology &<br />

Immunogenetics, Joslin Diabetes Center, Boston, MA, USA<br />

17:36 456. MRI of Cells & Mice At 1 & 7Tesla with Gd-Targeting Agents: When the Low Field is Better!<br />

Simonetta Geninatti-Crich 1 , Diego Alberti 1 , Ibolya Szabo 1 , Dario Longo 1 , Silvio Aime 1<br />

1 University of Torino, Torino, Italy<br />

17:48 457. Enhanced Relaxivity of Hydroxyapatite-Targeted Gadolinium Contrast Agents<br />

Jonathan Marmurek 1,2 , Khaled Nasr 3 , Elena Vinogradov 2 , Ananth J. Madhuranthakam 4 , John V. Frangioni 3 , Robert E.<br />

Lenkinski 2<br />

1 Harvard-MIT Division of Health Sciences & Technology, Cambridge, MA, USA; 2 Radiology, Beth Israel Deaconess Medical Center,<br />

Harvard Medical School, Boston, MA, USA; 3 Hematology & Oncology, Beth Israel Deaconess Medical Center, Harvard Medical<br />

School, Boston, MA, USA; 4 Global Applied Science Laboratory, GE Healthcare, Boston, MA, USA<br />

Stroke - Clinical Studies<br />

Room 512A-G 16:00-18:00 Moderators: Jeffry R. Alger & Charlotte Rosso<br />

16:00 458. Ischemic Penumbra in Acute MCA Stroke: Comparison of the PWI-DWI Mismatch & the ADC-Based<br />

NEURINFARCT Methods<br />

Aurelie Drier 1,2 , Thomas Tourdias 3 , Igor Sibon 4 , Yohan Attal 5 , Gurkan Mutlu 6 , Stéphane Lehéricy 1,2 , Yves Samson 6 ,<br />

Jacques Chiras 1 , Didier Dormont 1 , Jean-Marc Orgogozo 4 , Vincent Dousset 3 , Charlotte Rosso 6<br />

1 Neuroradiology, Pitié Salpêtrière Hospital, Paris, France; 2 Centre de NeuroImagerie de Recherche - CENIR,CRICM U795, Paris,<br />

France; 3 Neuroradiology, CHU Pellegrin, Bordeaux, France; 4 Neurology, CHU Pellegrin, Bordeaux, France; 5 CRICM, CNRS,<br />

UMR7225 équipe NEMESIS, Paris, France; 6 Urgences cérébro-vasculaires, Pitié Salpêtrière Hospital, Paris, France<br />

16:12 459. Bolus Delay & Dispersion in Predictor Models in Acute Stroke<br />

Lisa Willats 1 , Alan Connelly 1,2 , Soren Christensen 3,4 , Geoffrey Donnan 2,5 , Stephen Davis 4,6 , Fernando Calamante 1,2<br />

1 Brain Research Institute, Florey Neuroscience Institutes , Melbourne, Australia; 2 Department of Medicine, University of Melbourne,<br />

Australia; 3 Department of Radiology, University of Melbourne, Australia; 4 Royal Melbourne Hospital, Melbourne, Australia; 5 Florey<br />

Neuroscience Institutes, Melbourne, Australia; 6 Department of Neurology, University of Melbourne, Australia<br />

16:24 460. Comparison of Pseudo-Continuous Arterial Spin-Labeled & Dynamic Susceptibility Contrast Enhanced<br />

Perfusion Imaging in Acute Ischemic Stroke<br />

Danny J. J. Wang 1 , David S. Liebeskind 1 , Qing Hao 1 , Joe X. Qiao 2 , Rana Fiazv 1 , Matthias Gunther 3,4 , Whitney B.<br />

Pope 2 , Samuel Hou 2 , Lirong Yan 1 , Jeffrey L. Saver 1 , Noriko Salamon 2 , Jeffry R. Alger 1,2<br />

1 Neurology, UCLA, Los Angeles, CA, USA; 2 Radiology, UCLA, Los Angeles, CA, USA; 3 Faculty of Physics & Electronics,<br />

University of Bremen, Bremen, Germany; 4 Fraunhofer MEVIS-Institute for Medical Image Computing, Bremen, Germany<br />

16:36 461. Reversal of Abnormal ADC Lags Reperfusion & Does Not Necessarily Represent Tissue Salvage<br />

Hongyu An 1 , Andria L. Ford 2 , Katie D. Vo 3 , William J. Powers 4 , Jin-Moo Lee 2 , Weili Lin 1<br />

1 Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; 2 Neurology, Washington University in St. Louis, St.<br />

Louis, MO, USA; 3 Radiology, Washington University in St. Louis, St. Louis, MO, USA; 4 Neurology, University of North Carolina at<br />

Chapel Hill, Chapel Hill, NC, USA<br />

65

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