Poster <strong>Session</strong>s Breast 130 1 Fondazione IRCCS Ist. Nazionale Tumori, Milano, Mi, Italy; 2 Cell Biology & Neurosciences, Istituto Superiore di Sanità, Roma, RM, Italy; 3 John Hopkins University, Baltimore, MA, United States 997. Endothelial Cell Proliferation is Not Affected by Downregulation of Choline Kinase Noriko Mori 1 , Mayur Gadiya 2 , Flonne Wildes 2 , Balaji Krishnamachary 2 , Zaver M. Bhujwalla 2 1 JHU ICMIC Program, The Russell H. Morgan Department of Radiology & Radiological Science, The Johns Hopkins University, School of Medicine , Baltimore, MD, United States; 2 JHU ICMIC Program, The Russell H. Morgan Department of Radiology & Radiological Science, The Johns Hopkins University, School of Medicine, Baltimore, MD, United States 998. Inflammation & Choline Metabolism Are Linked in Breast Cancer Ioannis Stasinopoulos 1 , Tariq Shah 1 , Yelena Mironchik 1 , Balaji Krishnamachary 1 , Zaver M. Bhujwalla 1,2 1 JHU ICMIC Program, Russell H. Morgan Department of Radiology & Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, United States; 2 The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD, United States 999. Comparison of NMR Lipid Profiles in Mitotic Arrest & Apoptosis as Indicators of Drug Resistance. Dominik Zietkowski 1 , Eszter Nagy 2 , Margaret A. Mobberley 3 , Geoffrey S. Payne 4 , Timothy A. Ryder 3 , Nandita M. de Souza 4 1 CRUK & EPSRC Cancer Imaging Centre , The Institute of Cancer Research, Sutton, Surrey, United Kingdom; 2 Section of Molecular Carcinogenesis, The Institute of Cancer Research, Sutton, Surrey, United Kingdom; 3 Department of Cellular Pathology, Imperial College Healthcare NHS Trust, London, United Kingdom; 4 CRUK & EPSRC Cancer Imaging Centre, The Institute of Cancer Research, Sutton, Surrey, United Kingdom 1000. The Metabolic Profile of Drug-Induced Autophagy in Cancer Gigin Lin 1 , Helen Troy 1 , Lauren Elizabeth Jackson 1 , Ian R. Judson 2 , John R. Griffiths 3 , Dow-Mu Koh 1 , Simon P. Robinson 1 , Martin O. Leach 1 , Yuen-Li Chung 1 1 CRUK & EPSRC Cancer Imaging Centre, Institute of Cancer Research & Royal Marsden Hospital, Sutton, Surrey, United Kingdom; 2 CRUK Centre of Cancer Therapeutics Unit, Institute of Cancer Research and Royal Marsden Hospital, Sutton, Surrey, United Kingdom; 3 CRUK Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom 1001. The Pi3K Inhibitor Ly294002 Downregulates Akt Phosphorylation & Reduces Cell Proliferation Without Decreasing the Phosphocholine Level in Ovarian Cancer Cells Egidio Iorio 1 , Chiara Alberti 2 , Paola Alberti 2 , Alessandro Ricci 1 , Maria Elena Pisanu 1 , Patrizia Pinciroli 2 , Silvana Canevari 2 , Franca Podo 1 , Antonella Tomasetti 2 1 2 Cell Biology & Neurosciences, Istituto Superiore di Sanità, Roma, RM, Italy; Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy 1002. Potential of 31 P Magnetic Resonance Spectroscopy of Bile in the Detection of Cholestatic Diseases Omkar B. Ijare 1 , Tedros Bezabeh 1 , Nils Albiin 2 , Annika Bergquist 2 , Urban Arnelo 2 , Matthias Lohr 2 , Ian C. P. Smith 1 1 2 National Research Council Institute for Biodiagnostics, Winnipeg, Manitoba, Canada; Karolinska University Hospital, Karolinska Institutet, Huddinge, Stockholm, Sweden 1003. Investigation of Mobile Lipid Resonances in Cervical Tissue Biopsies & Correlation with Cytoplasmic Lipid Droplets. Dominik Zietkowski 1 , Geoffrey Payne 2 , Nandita deSouza 2 1 CRUK & EPSRC Cancer Imaging Centre , The Institute of Cancer Research, Sutton, Surrey, United Kingdom; 2 CRUK & EPSRC Cancer Imaging Centre, The Institute of Cancer Research, Sutton, Surrey, United Kingdom 1004. Intracellular Selective Acidification of Human Melanoma Xenografts by Lonidamine: a 31 P Magnetic Resonance Spectroscopy Study Kavindra Nath 1 , David S. Nelson 1 , Andrew Ho 1 , Brian P. Weiser 2 , Rong Zhou 1 , Stephen Pickup 1 , Lin Z. J. Li 1 , Deenis Leeper 3 , Jerry D. Glickson 1 1 Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2 Pharmacology, University of Pennsylvania, Philadelphia, PA, United States; 3 Radiation Oncology, Thomas Jefferson University, Philadelphia, PA, United States Exhibition Hall <strong>Monday</strong> 14:00-16:00 1005. Magnetization Transfer Imaging of the Healthy Breast at 3T Lori R. Arlinghaus 1,2 , Richard D. Dortch 1,2 , Adrienne N. Dula 1,2 , Seth A. Smith 1,2 , John C. Gore 1,2 , Thomas E. Yankeelov 1,2 1 Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States; 2 Department of Radiology & Radiological Sciences, Vanderbilt University, Nashville, TN, United States
Poster <strong>Session</strong>s 1006. Consistency of Breast Density Measured from the Same Women using Different MR Scanners at 1.5T & 3.0T Jeon-Hor Chen 1,2 , Siwa Chan 3 , Daniel H-E Chang 1 , Muqing Lin 1 , Orhan Nalcioglu 1 , Min-Ying L. Su 1 1 Center for Functional Onco-Imaging & Department of Radiological Science, University of California Irvine, Irvine, CA, United States; 2 Department of Radiology, China Medical University Hospital, Taichung, Taiwan; 3 Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan 1007. Different Types of Errors in Segmentation of Breast Density using Computer-Aided Algorithms Jeon-Hor Chen 1,2 , Muqing Lin 1 , Fu-Ju Lei 2 , Jia-Pei Wu 2 , Siwa Chan 3 , Orhan Nalcioglu 1 , Min-Ying L. Su 1 1 Center for Functional Onco-Imaging & Department of Radiological Science, University of California Irvine, Irvine, CA, United States; 2 Department of Radiology, China Medical University Hospital, Taichung, Taiwan; 3 Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan 1008. Rapid Dixon Estimation of Water & Fat Equilibrium Magnetisation for Breast Density Measurements Maria a Schmidt 1 , Antonio de Stefano 2 , Erica Scurr 1 , James d'Arcy 1 , Martin O. Leach 1 1 Cancer Research UK & EPSRC Cancer Imaging Centre, Royal Marsden NHS Foundation Trust & Institute of Cancer Research, Sutton, England, United Kingdom; 2 Medical Physics, Portsmouth NHS Hospitals Trust, Portsmouth, England, United Kingdom 1009. Bilateral Breast Imaging using IDEAL Fat-Water Separation & an Undersampled 3D Radial BSSFP Acquisition Leah C. Henze-Bancroft 1 , Catherine J. Moran 2 , Scott B. Reeder 3,4 , Frederick Kelcz 4 , Walter F. Block 3 1 Department of Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, United States; 2 Department of Radiology, Stanford University, Stanford, CA; 3 Department of Medical Physics, University of Wisconsin - Madison, Madison, WI; 4 Department of Radiology, University of Wisconsin - Madison, Madison, WI 1010. Associations of Breast MR Derived Vascular, Shape & Texture Parameters with Histological Prognostic Indicators Martin D. Pickles 1 , Peter Gibbs 1 , Martin Lowry 1 , Lindsay W. Turnbull 1 1 Centre for MR Investigations, University of Hull, Hull, East Yorkshire, United Kingdom 1011. Diffusion Tensor Based Reconstruction of the Ductal Tree Marco Reisert 1 , Matthias Weigel 1 , Erez Eyal 2 , Dov Grobgeld 2 , Hadassa Degani 2 , Jürgen Hennig 1 1 Medical Physics, University Medical Center Freiburg, Freiburg, Baden Württemberg, Germany; 2 Biological Regulation Dept., Weizmann Institute of Science, Rehovot, Israel 1012. Dynamic Contrast-Enhanced Breast MRI using Flexible Radial Undersampling with Compressed Sensing Reconstruction Rachel Waichung Chan 1 , Elizabeth Anne Ramsay 2 , Edward Yiuwah Cheung 3 , Donald Bruce Plewes 1,2 1 Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; 2 Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; 3 University of Waterloo, Waterloo, Ontario, Canada 1013. Novel DCE-MRI Technique: Application to Breast Cancer Dmitri Artemov 1 , Wenlian Zhu 1 , Yoshinori Kato 1 1 Radiology, Johns Hopkins University, Baltimore, MD, United States 1014. Quantitative Magnetic Susceptibility Mapping (QSM) in Breast Disease Reveals Additional Information for MR-Based Characterization of Carcinoma & Calcification Ferdinand Schweser 1,2 , Karl-Heinz Herrmann 1 , Andreas Deistung 1 , Marie Atterbury 1,3 , Pascal A. Baltzer, Hartmut Peter Burmeister, Werner Alois Kaiser, Jürgen R. Reichenbach 1 1 Medical Physics Group, Dept. of Diagnostic & Interventional Radiology 1, Jena University Hospital, Jena, Germany; 2 School of Medicine, Friedrich Schiller University of Jena, Jena, Germany; 3 Dept. of Physics, Brown University, Providence, RI, United States 1015. Multicenter, Double-Blind, Randomized, Intraindividual Crossover Comparison of Gadobenate Dimeglumine & Gadopentetate Dimeglumine for MR Imaging of the Breast (DETECT) Laura Martincich 1 , Matthieu Faivre-Pierret 2 , Christian M. Zechmann 3 , Stefano Corcione 4 , Harrie C. M. van Den Bosch 5 , Wei-Jun Peng 6 , Antonella Petrillo 7 , Katja Siegmann 8 , Johannes T. Heverhagen 9 , Pietro Panizza 10 , Hans-Björn Gehl 11 , Felix Diekmann 12 , Federica Pediconi 13 , Lin Ma 14 , Fiona J. Gilbert 15 , Francesco Sardanelli 16 , Paolo Belli 17 1 Department of Diagnostic Imaging, Institute for Cancer Research & Treatment (IRCC), Candiolo, Torino, Italy; 2 Center Oscar Lambret, Lille, France; 3 German Cancer Research Center, Heidelberg, Germany; 4 University Hospital “S. Anna”, Ferrara, Italy; 5 Catharina Hospital, Eindhoven, Netherlands; 6 Cancer Hospital, Fudan University, Shanghai, China, People's Republic of; 7 National Cancer Institute, Fondazione G. Pascale, Napoli, Italy; 8 University Hospital Tuebingen, Tuebingen, Germany; 9 University Hospital, Philipps University, Marburg, Germany; 10 Ospedale San Raffaele, Milano, Italy; 11 Klinikum Bielefeld, Bielefeld, Germany; 12 Universitätsklinikum Charité, Berlin, Germany; 13 University of Rome “La Sapienza”, Rome, Italy; 14 Chinese People's Liberation Army (PLA) General Hospital, Beijing, China, People's Republic of; 15 Aberdeen Biomedical Imaging Centre, Aberdeen, United Kingdom; 16 Policlinico San Donato, San Donato Milanese, Italy; 17 Institute of Radiology, "A. Gemelli", Rome, Italy 1016. Ultrafast Dynamic Imaging of the Breast at Diagnostic Spatial Resolution using TWIST Ritse M. Mann 1 , Roel D. M. Mus 1 , Christian Geppert 2 , Jelle O. Barentsz 1 , Henkjan Huisman 1 131
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