Monday AM 1 Opening Session 2011 Mansfield Lecture ... - ISMRM

Friday AM
Sunrise Educational Course
Absolute Beginners' Guide to Anatomical & Functional MRI of the Brain
Room 710B 07:00-08:00 Moderator: Thomas T. Liu
07:00 Perfusion Imaging
Matthias Günther
07:30 Perfusion Processing
Michael A. Chappell
Plenary Lectures
MRI in the Compromised Pregnancy
Plenary Hall 08:15-09:30 Organizers: Penny Anne Gowland & Evis Sala
08:15 691. The Problems of Managing the Compromised Pregnancy
Phillip N. Baker
University of Alberta, Edmonton, AB, Canada
One in five first pregnancies is complicated by a major pregnancy complication, often without preceding signs or symptoms. the placenta
is key to the pathogenesis of two of these complications, preeclampsia and fetal growth restriction (FGR), and this provides the opportunity
for predictive and diagnostic tests. Current methodologies include placental hormone measurement, ultrasound assessment of placental
morphology and uterine artery Doppler. Once a diagnosis of preeclampsia/FGR has been made, ultrasound assessment of fetal growth and
wellbeing is a crucial determinant of the timing of delivery. the role of MR assessment of the placenta is unproven.
08:35 692. Novel MR for Fetal Morphometry
Colin Studholme
University of Washington, Seattle, WA, USA
Advances in MRI and post processing have revolutionized our ability to quantify early human brain growth in-utero. Motion correction of
fast multi-slice imaging permits the formation of true 3D images of the moving fetal head in the majority rather than a fraction of cases,
and allows large scale studies of normal human fetal brain growth. New methods allow automated morphometric analysis of transient
tissue zones. These studies reveal the process of early sulcal formation, the emergence of brain asymmetry in-utero and promise to provide
a host of focal biomarkers that can be used to probe neurological development in clinical cases.
09:05 693. Fetal MR- Beyond Morphology
Daniela Prayer
Medical University of Vienna, Vienna, Austria
Diffusion-tensor imaging and tractography, fMRI diffusion-based perfusion measurements, spectroscopy, and dynamic movement studies
can be used prenatally to acquire information about normal and pathological maturational processes that exceed the visualization of pure
morphological details. These applications have become possible as a consequence of speeding up sequences that may be used in unsedated
fetuses. the additional information provided by these methods do not only enhance the understanding of normal developmental processes,
they also offer opportunities to recognize disorders of normal development earlier, describe them more accurately, and thus improve the
quality of counseling and perinatal management.
Animal Models of Brain Disease Other than Stroke
Room 510 10:30-12:30 Moderators: Emmanuel L. Barbier & Youssef Z. Wadghiri
10:30 694. Neuroanatomical Abnormalities in a Neuroligin 3 R451C Knockin Mouse Model of Autism
Jacob Ellegood 1 , Jason P. Lerch 1 , R. M. Henkelman 1
1 Mouse Imaging Centre, the Hospital for Sick Children, Toronto, Ontario, Canada
10:42 695. High-Field (9.4 T) MRI of Brain Dysmyelination by Quantitative Mapping of Magnetic Susceptibility
Chunlei Liu 1,2 , Wei Li 1 , G. Allan Johnson 2 , Bing Wu 1
1 Brain Imaging and Analysis Center, Duke University, Durham, NC, USA; 2 Radiology, Duke University, Durham, NC, USA
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