Poster <strong>Session</strong>s 294 2754. Multi-Parameter Mapping of the Human Cervical Cord at 3.0T in Less than 20 Minutes Rebecca Sara Samson 1 , Olga Ciccarelli 2 , Carolina Kachramanoglou 2 , Antoine Lutti 3 , David J. L. Thomas 2 , Nikolaus Weiskopf 3 , Claudia A. M. Wheeler-Kingshott 1 1 Department of Neuroinflammation, UCL Institute of Neurology, London, England, United Kingdom; 2 Department of Brain Repair & Rehabilitation, UCL Institute of Neurology, London, England, United Kingdom; 3 Functional Imaging Laboratory, UCL Institute of Neurology, London, England, United Kingdom 2755. A New 3D Method for Water and Relaxation Time Mapping: Comparison to the 2D “gold Standard” Ana Maria Oros-Peusquens 1 , Fabian Keil 1 , Vincent Gras 1 , Zaheer Abbas 1 , Daniel Brenner 1 , Miriam Rabea Kubach 1 , Klaus Hans Mannfred Möllenhoff 1 , Nadim Jon Shah 1,2 1 Institute of Neuroscience & Medicine - 4, Forschungszentrum Juelich, Juelich, Germany; 2 Department of Neurology, Faculty of Medicine, JARA, RWTH Aachen University, Aachen, Germany 2756. Evaluation of Principal Component Model-Based Algorithm for T 2 Estimation of Small Objects Chuan Huang 1 , Christian G. Graff 2 , Ali Bilgin 3,4 , Maria I. Altbach 5 1 Mathematics, University of Arizona, Tucson, AZ, United States; 2 Division of Imaging & Applied Mathematics, Food & Drug Administration; 3 Biomedical Engineering, University of Arizona; 4 Electrical & Computer Engineering, University of Arizona; 5 Radiology, University of Arizona 2757. Spatially Resolved Two-Dimensional T 1-T 2 Relaxometry in the Human Brain using Inversion-Recovery Spin- Echo Measurements & NNLS Valentin Gereon Kemper 1 , Ana-Maria Oros-Peusquens 1 , Nadim Jon Shah 1,2 1 Institute of Neuroscience & Medicine, Research Centre Juelich, Juelich, 52425, Germany; 2 Department of Neurology, Faculty of Medicine, JARA, RWTH Aachen University, Aachen, 52074, Germany 2758. Fast Proton Density Mapping using Bias Field Correction Steffen Volz 1 , Ulrike Nöth 1 , Ralf Deichmann 1 1 Brain Imaging Center (BIC), Goethe University Frankfurt, Frankfurt, Germany 2759. A Novel Method for Characterizing T 2 Spectra Marshall S. Sussman 1 , Walter Kucharczyk 1 1 Medical Imaging, University Health Network, Toronto, Ontario, Canada 2760. Comparison of Two MRI-UTE Sequences for the Quantification (T 1) of the Human Achilles Tendon Peter Wright 1 , Richard Hodgson 2 , Vladimir Jellus 3 , Lars Lauer 3 , Matthew Robson 4 1 LMBRU, Leeds Teaching Hospitals NHS Trust, Leeds, Yorkshire, United Kingdom; 2 LMBRU, University of Leeds, United Kingdom; 3 Siemens AG, Erlangen, Germany; 4 University of Oxford, United Kingdom 2761. Transverse Relaxometry with Non-180° Refocusing Pulses Julien Sénégas 1 , Nicolas Neu 2 , Jochen Keupp 1 1 Philips Research Laboratories, Hamburg, Germany; 2 Ecole des Mines de Paris, France 2762. A Four Parameter Fitting Method to Quantify Fully the Sources of Phase Contrast in Gradient Echo MRI Sam Wharton 1 , Richard Bowtell 1 1 Sir Peter <strong>Mansfield</strong> Magnetic Resonance Centre, University of Nottingham, Nottingham, United Kingdom 2763. Region Based Joint Bi-Exponential T 2 Fitting for Small Lesions Chuan Huang 1 , Christian G. Graff 2 , Eric W. Clarkson 3,4 , Ali Bilgin 5,6 , Maria I. Altbach 3 1 Mathematics, University of Arizona, Tucson, AZ, United States; 2 Division of Imaging & Applied Mathematics, Food & Drug Administration; 3 Radiology, University of Arizona; 4 Optical Sciences, University of Arizona; 5 Biomedical Engineering, University of Arizona; 6 Electrical & Computer Engineering, University of Arizona 2764. Accurate T 1 & T 2 Quantification in Look-Locker 2D SSFP Imaging with Flip Angle Profile Correction Mitchell Anthony Cooper 1,2 , Thanh D. Nguyen 3 , Pascal Spincemaille 3 , Martin R. Prince 3 , Jonathan W. Weinsaft 4 , Yi Wang 1,3 1 Biomedical Engineering, Cornell University, Ithaca, NY, United States; 2 Radiology, Weill Cornell Medical College , New York, United States; 3 Radiology, Weill Cornell Medical College, New York, United States; 4 Cardiology, Weill Cornell Medical College, New York, United States 2765. In Vivo T 2 Measurements of the Right Ventricle Inferior Wall: Comparison with the Left Ventricle Brice Fernandez 1,2 , Maelene Lohezic 1,2 , Lucien Hammen 2,3 , Marine Beaumont 4,5 , Damien Mandry 2,4 , Pierre-André Vuissoz 2,3 , Jacques Felblinger 2,3 1 Global Applied Science Laboratory, GE Healthcare, Nancy, France; 2 IADI Lab, Nancy-Université, Nancy, France; 3 U947, INSERM, Nancy, France; 4 CHU de Nancy, Nancy, France; 5 CIT801, INSERM, Nancy, France
Chemical Exchange Saturation Transfer Exhibition Hall <strong>Monday</strong> 14:00-16:00 2766. Feasibility of CEST Imaging on the Guinea Pig Stifle at 9.4 T Matthew Fenty 1 , Victor Babu Kassey 1 , Feliks Kogan 1 , Ravinder Reddy 1 1 CMROI, Radiology, University of Pennsylvania, Philadelphia, PA, United States Poster <strong>Session</strong>s 2767. Chemical Exchange Saturation Transfer Effect from Phospho-Creatine (PCr) & Adenosine-Tri-Phosphate (ATP) Mohammad Haris 1 , Kejia Cai 1 , Anup Singh 1 , Victor Babu Kc 1 , Hari Hariharan 1 , Ravinder Reddy 1 1 CMROI, Radiology, University of Pennsylvania, Philadelphia, PA, United States 2768. Quantitative Modeling of In-Vivo Amide Proton Transfer Measurements in the Human Brain Indicates a Dominant Signal Contribution from Proteins with Short T2 Relaxation Times Rachel Scheidegger 1,2 , Elena Vinogradov 1,3 , Weiying Dai 1,3 , David C. Alsop 1,3 1 Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States; 2 Health Sciences & Technology, Harvard-MIT, Cambridge, MA, United States; 3 Radiology, Harvard Medical School, Boston, MA, United States 2769. Amide Proton Transfer Imaging with Continuous Wave Dual Frequency Saturation Can Detect the Amide Proton Peak in the Z-Spectrum Acquired at 3T Rachel Scheidegger 1,2 , Elena Vinogradov 1,3 , Weiying Dai 1,3 , David C. Alsop 1,3 1 Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States; 2 Health Sciences & Technology, Harvard-MIT, Cambridge, MA, United States; 3 Radiology, Harvard Medical School, Boston, MA, United States 2770. Optimization of Pulsed-GagCEST at 3.0T Gopal Varma 1 , David C. Alsop 1 , Robert E. Lenkinski 1 , Elena Vinogradov 1 1 Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States 2771. Chemical Exchange Transfer Imaging of Creatine Anup Singh 1 , Mohammad Haris 1 , Kejia Cai 1 , Hari Hariharan 1 , Ravinder Reddy 1 1 CMROI, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States 2772. High Resolution Imaging of Myo-Insitol in Alzhemier’s Disease Pathology Mohammad Haris 1 , Anup Singh 1 , Kejia Cai 1 , Kavindra Nath 2 , Rachelle Berger 1 , Ari Borthakur 1 , Hari Hariharan 1 , Ravinder Reddy 1 1 CMROI, Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2 LMI, Radiology, University of Pennsylvania 2773. CEST MRI of Human Liver at 3T Kejia Cai 1 , Anup Singh 1 , Kalli Grasley 1 , Mohammad Haris 1 , Damodar Reddy 1 , Hari Hariharan 1 , Ravinder Reddy 1 1 CMROI, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States 2774. Identification of Endogenous Proteins Correlated with Amide Proton Transfer (APT) Imaging Contrast using Proteomic Analysis Kun Yan 1 , Zongming Fu 2 , Jennifer Van Eyk 3 , Silun Wang 1 , Jinyuan Zhou 1 1 Radiology, Johns Hopkins University, Baltimore, MD, United States; 2 Pediatrics, Johns Hopkins University, Baltimore, MD, United States; 3 Bayview Proteomics Center, Johns Hopkins University, Baltimore, MD, United States 2775. Keyhole Chemical Exchange Saturation Transfer Gopal Varma 1 , Robert E. Lenkinski 1 , Elena Vinogradov 1 1 Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States 2776. 3D Whole Brain Pulsed CEST Acquisition at 7T Craig K Jones 1,2 , Daniel Polders 3 , Jun Hua 1 , Hans Hoogduin 4 , He Zhu 1 , Jinyuan Zhou 1,2 , Peter C. M. van Zijl 1,2 1 FM Kirby Center, Kennedy Krieger Institute, Baltimore, MD, United States; 2 Department of Radiology & Radiological Sciences, Johns Hopkins Medical Institutes, Baltimore, MD, United States; 3 Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands; 4 Brain Division, University Medical Center Utrecht, Utrecht, Netherlands 2777. Computational Modeling & Optimized Detection of PARACEST Contrast Agents with Echo Planar Imaging Nevin McVicar 1,2 , Alex Li 2 , Adrienne Campbell 3 , Marty Klassen 2 , Rob Bartha 1,2 1 Medical Biophysics, University of Western Ontario, London, ON, Canada; 2 Centre for Functional & Metabolic Mapping, Robarts Research Institute; 3 Division of Medicine & Institute of Child Health, UCL Centre for Advanced Biomedical Imaging, London, United Kingdom 2778. Modeling MT Effect of Bound Water Pool & Its Use in Correction of CEST Contrast for MT Asymmetry Anup Singh 1 , Kejia Cai 1 , Mohammad Haris Haris 1 , Hari Hariharan 1 , Ravinder Reddy 1 1 CMROI, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States 295
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