Poster <strong>Session</strong>s 124 939. Gadolinium Exposure Before or After Liver Transplantation: No Excess Risk of Nephrogenic Systemic Fibrosis (NSF)? Elise Eva Saddleton 1 , Anne Laumann 2 , Dennis P. West 2 , Steven M. Belknap 3 , Brenda Schmitz 1 , Beatrice J. Edwards 3 , Nicole Papariello 2 , Michael I. Abecassis 4 , Frank H. Miller 1 1 2 Radiology, Northwestern University, Chicago, IL, United States; Dermatology, Northwestern University, Chicago, IL, United States; 3 4 Medicine, Northwestern University, Chicago, IL, United States; Transplant Surgery, Northwestern University, Chicago, IL, United States 940. Nephrogenic Systemic Fibrosis: Portrait in the Medical Literature Gianpaolo Pirovano 1 , Cindy Schultz 2 , John R. Parker 2 , Miles A. Kirchin 3 , Alberto Spinazzi 1 1 Worldwide Medical Affairs, Bracco Diagnostics Inc., Princeton, NJ, United States; 2 Medical Communications, Bracco Diagnostics Inc., Princeton, NJ, United States; 3 Medical Communications, Bracco Imaging, Milan, Italy 941. Combined Off-Resonance Imaging & Relaxation in the Rotating Frame for Positive Contrast Imaging of Infection in a Murine Burn Model Testing a Novel Anti-Infective Compound Valeria Righi 1,2 , Melissa Starkey 3 , Jianxin He 3 , George Dai 2 , Vitaliano Tugnoli 4 , Laurence G. Rahme 3 , Ronald G. Tompkins 5 , Aria A. Tzika 1,2 1 Department of Surgery, NMR Surgical Laboratory, MGH & Shriners Burn Institute, Harvard Medical School, Boston, MA, United States; 2 Department of Radiology, Athinoula A. Martinos Center of Biomedical Imaging, Boston, MA, United States; 3 Department of Surgery, Molecular Surgery Laboratory, MGH & Shriners Burn Institute, Harvard Medical School, Boston, MA, United States; 4 Departement of Biochemistry, University of Bologna, Bologna, Italy; 5 Department of Surgery, MGH & Shriners Burn Institute, Harvard Medical School, Boston, MA, United States 942. Development of Nanoparticle-Based Magnetic Resonance Colonography Jihong Sun 1,2 , Weiliang Zheng 1 , Hong Yuan 3 , Tao Wu 1 , Xiaoming Yang 1,2 , Shizheng Zhang 1 1 Radiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China, People's Republic of; 2 Radiology, University of Washington School of Medicine, Seattle, WA, United States; 3 College of Pharmaceutical Science, Zhejiang University, Hangzhou, Zhejiang, China, People's Republic of Body - Animal Models Exhibition Hall Tuesday 13:30-15:30 943. 1 H-MRS Can Be Used to Investigate Creatine Metabolism in Multiple Organs Within a Single Examination in the Mouse Kiterie Maud Faller 1 , Craig A. Lygate 1 , Stefan Neubauer 1 , Jurgen E. Schneider 1 1 Cardiovascular Medicine, University of Oxford, Oxford, Oxfordshire, United Kingdom 944. Characterization of Liver Fibrosis by 1 H- & 31 P-MRS in CCl4-Treated Rats Yunjung Lee 1 , Hyungjoon Noh 1 , Keunhyung Kang 1 , Ok-Hee Kim 1 , Byung-Chul Oh 1 , Hyeonjin Kim 2 1 Lee Gil Ya Cancer & Diabetes Institute, Gachon University of Medicine & Science, Incheon, Korea, Republic of; 2 Radiology, Seoul National University Hospital, Seoul, Korea, Republic of 945. A New Technique for the Detection of Liver Damage by Evaluation of Impaired Exocytotic Activity of Kupffer Cells; an Experimental Study of Gadolinium Chloride-Induced Liver Injury in Rats Toshihiro Furuta 1,2 , Masayuki Yamaguchi 1 , Ryutaro Nakagami 1,3 , Masaaki Akahane 2 , Manabu Minami 4 , Kuni Ohtomo 2 , Hirofumi Fujii 1 1 Functional Imaging Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Japan; 2 Department of Radiology, The University of Tokyo Hospital, Tokyo, Japan; 3 Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan; 4 Department of Radiology, Tsukuba University Hospital, Tsukuba, Japan 946. Imaging of Hepatic Steatosis & Hyperpolarized Carbon Metabolism at 14T - Applications to a Murine Model of Non-Alcoholic Fatty Liver Disease Andrew G. Taylor 1 , Kayvan Keshari 1 , Robert Bok 1 , Subramaniam Sukumar 1 , Aliya Qayyum 1 , John Kurhanewicz 1 1 Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States 947. Comparison of Gd-DTPA & Gd-BOPTA for Studying Renal Perfusion & Filtration Mike Notohamiprodjo 1 , Michael Pedersen 2 , Christian Glaser 3 , Andreas D. Helck, Klaus-Peter Lodemann 4 , Bente Jespersen 5 , Michael Fischereder 6 , Maximilian F. Reiser, Steven P. Sourbron 7 1 Department of Clinical Radiology, University Hospitals Munich, Munich, Bavaria, Germany; 2 MR Research Centre, Aarhus University Hospital; 3 Department of Radiology, NYU Langone Medical Center; 4 Bracco Imaging Germany; 5 Department of Nephrology, Aarhus University Hospital; 6 Department of Nephrology, University Hospitals Munich; 7 Division of Medical Physics, University of Leeds
Poster <strong>Session</strong>s 948. MRI Biomarkers for Monitoring Progression in CKD: Preliminary Experience in a Reversible UUO Mouse Model Muhammad E. Haque 1 , Tammy Franklin 1 , Ujala Bokhary 1 , Liby Mathew 2 , Anthony Chang 3 , Tipu Puri 2 , Pottumarthi V. Prasad 1,4 1 Radiology, NorthShore University HealthSystem, Evanston, IL, United States; 2 Nephrology, University of Chicago, Chicago, IL; 3 Pathology, University of Chicago, Chicago, IL; 4 Radiology, University of Chicago, Chicago, IL, United States 949. MRI Characterization of Pathophysiological Changes in a Mouse Model of Acute Kidney Injury (AKI) Andreas Pohlmann 1 , Lajos Marko 2 , Babette Wagenhaus 1 , Uwe Hoff 3 , Erdmann Seeliger 4 , Dominik N Mueller 5 , Thoralf Niendorf 1 1 Berlin Ultrahigh Field Facility, Max Delbrueck Center for Molecular Medicine, Berlin, Germany; 2 Experimental & Clinical Research Center , Charité University Medicine, Berlin, Germany; 3 Clinic for Nephrology, Charité University Medicine, Berlin, Germany; 4 Institute of Vegetative Physiology, Charité University Medicine, Berlin, Germany; 5 Experimental & Clinical Research Center, Charité University Medicine, Berlin, Germany 950. Real-Time Multi-Slice MRI of Renal Filtration in the Mouse Amir Moussavi 1 , Martin Uecker 1 , Tilman Johannes Sumpf 1 , Roland Tammer 1,2 , Jens Frahm 1 , Susann Boretius 1 1 Biomedizinische NMR Forschungs GmbH am Max-Planck-Institut fuer biophysikalische Chemie, Goettingen, Germany; 2 DFG Research Center for Molecular Biology of the Brain (CMPB), Goettingen, Germany Cancer Animal Models - Characterization & Response Exhibition Hall Wednesday 13:30-15:30 951. In Vivo Imaging & Metabolism of Hyperpolarized 13 C Diethyl Succinate in Mice Niki Zacharias 1,2 , Napapon Sailasuta 3 , Henry Chan 3 , Meng Wei 3 , Robert W. Grubbs 1 , Brian D. Ross 3 , Pratip Bhattacharya 3 1 California Institute of Technology, Pasadena, CA, United States; 2 Enhanced Magnetic Resonance Laboratory, Huntington Medical Research Institutes, Pasadena, CA, United States; 3 Enhanced Megnetic Resonance Laboratory, Huntington Medical Research Institutes 952. Hyperpolarized 13 C MR Imaging & Corresponding Histopathology for the Non-Invasive Characterization of Metabolism in the TR<strong>AM</strong>P Model Kayvan R. Keshari 1 , Robert Bok, Subramaniam Sukumar, Mark Van Criekinge, Daniel Vigneron, John Kurhanewicz 1 UCSF, San Francisco, CA, United States 953. Optimized SPION Formulations for Molecular MRI of the Lung using Hyperpolarized Gases Rosa Tamara Branca 1 , Simone Degan, John Nouls 2 , Challa Kumar 3 , Sanchita Biswas 3 , Bastiaan Driehuys 2 1 Chemistry, Duke University, Durham, NC, United States; 2 Center for In Vivo Microscopy, Duke University; 3 Center for Advanced Microstructures & Devices, Louisiana State University, United States 954. Bifunctional Iron Oxide Nanoparticles for MR Imaging & Hyperthermia Therapy in Cancer Katherine Louise Parcell 1,2 , Tammy Louise Kalber 1,2 , Paul Southern 3 , Quentin a Pankhurst 3 , Sam M Janes 2 , Mark F. Lythgoe 1 1 UCL Centre for Advanced Biomedical Imaging, Division of Medicine & Institute of Child Health, University College London, London, United Kingdom; 2 Centre for Respiratory Research, University College London, London, United Kingdom; 3 Davy-Faraday Research Laboratories, the Royal Institution of Great Britain, London, United Kingdom 955. Extra-Cranial Measurements of Amide Proton Transfer using Exchange-Modulated Point-Resolved Spectroscopy (EXPRESS) Simon Walker-Samuel 1 , Peter Johnson 2 , Barbara Pedley 2 , Mark F. Lythgoe* 1 , Xavier Golay* 3 1 UCL Centre for Advanced Biomedical Imaging, Department of Medicine & Institute of Child Health, University College London, London, United Kingdom; 2 Institute of Cancer, University College London, United Kingdom; 3 Institute of Neurology, University College London, United Kingdom 956. Promoted Growth of Brain Tumor with Severe Hemorrhage by the Transplantation of Neural Progenitor Cells Facilitated by SDF-1 Nai-Wei Yao 1,2 , Chiao-Chi V Chen 1,3 , Chen Chang 1,3 1 Functional & Micro-magnetic Resonance Imaging Center, Academic Sinica, Taipei, Taiwan; 2 Institute of Zoology, National Taiwan University, Taipei, Taiwan; 3 Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan 957. High Resolution Magnetic Resonance Elastography of Orthotopic Murine Glioma In Vivo Yann Jamin 1 , Jessica K. R. Boult 1 , Jeffrey C. Bamber 1 , Ralph Sinkus 2 , Simon P. Robinson 1 1 CRUK & EPSRC Cancer Imaging Centre, The Institute of Cancer Research & Royal Marsden NHS Trust, Sutton, United Kingdom; 2 INSERM U773, CRB3, Centre de Recherches Biomédicales Bichat-Beaujon, Paris, France 125
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