Thursday <strong>AM</strong> Iron Detection & Quantification Room 512A-G 10:30-12:30 10:30 Tissue Iron Detection & Quantification with MRI Jens H. Jensen 10:55 Clinical Introduction John F. Schenck 11:05 Brain Iron Deposition Joanna F. Collingwood 11:30 Cardiac Iron Deposition Claudia M. Hillenbrand 11:55 Liver Iron Bachir Taouli 12:20 Discussion Proton vs. Hyperpolarized-Gas MRI for Evaluating the Lung Room 513A-D 10:30-12:30 Moderators: Per A. G. Åkeson & Kiarash Emami 10:30 541. Validation of Ventilation- & Perfusion-Weighted Fourier Decomposition MRI with Hyperpolarized 3 He-MRI & Dynamic Contrast-Enhanced MRI in An Animal Experiment Grzegorz Bauman 1 , Alexander Scholz 2 , Julien Rivoire 2 , Maxim Terekhov 2 , Janet Friedrich 2 , Andre de Oliveira 3 , Wolfhard Semmler 1 , Laura M. Schreiber 2 , Michael Puderbach 4 1 Division of Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany; 2 Department of Radiology, Section of Medical Physics, Johannes Gutenberg University Medical Center, Mainz, Germany; 3 Siemens Healthcare, Erlangen, Germany; 4 Division of Radiology, German Cancer Research Center, Heidelberg, Germany 10:42 542. Heterogeneity of the Ventilation–Perfusion Ratio in Lung Disease using OE-MRI Penny Louise Hubbard 1,2 , Geoff J. M. Parker 1,2 , Dave Singh 3 , Eva Bondesson 4 , Lars E. Olsson 5 , Lars Wigström 5 , Simon S. Young 6 , Josephine H. Naish 1,2 1 Imaging Sciences & Biomedical Engineering, The University of Manchester, Manchester, United Kingdom; 2 The Biomedical Imaging Institute, The University of Manchester, Manchester, United Kingdom; 3 Airway Pharmacology Group, School of Translational Medicine, University Hospital of South Manchester Foundation Trust, Manchester, Greater Manchester, United Kingdom; 4 AstraZeneca R & D, Lund, Sweden; 5 AstraZeneca R & D, Möndal, Sweden; 6 AstraZeneca R & D, Charnwood, United Kingdom 10:54 543. Assessment of Relative Regional Lung Compliance in Patients with Chronic Obstructive Pulmonary Disease Alexandra Rose Morgan 1,2 , Geoff J. M. Parker 1,2 , Penny L. Hubbard 1,2 , David Singh 2,3 , Jørgen Vestbo 2,3 , Simon S. Young 4 , Eva Bondesson 5 , Lars Wigström 5 , Lars E. Olsson 6 , Marietta L. J. Scott 7 , Josephine H. Naish 1,2 1 Imaging Science & Biomedical Engineering, University of Manchester, Manchester, Greater Manchester, United Kingdom; 2 Biomedical Imaging Institute, University of Manchester, Manchester, Greater Manchester, United Kingdom; 3 Airway Pharmacology Group, School of Translational Medicine, University Hospital of South Manchester, Manchester, Greater Manchester, United Kingdom; 4 AstraZeneca R&D, Charnwood, United Kingdom; 5 AstraZeneca, Lund, Sweden; 6 AstraZeneca, Mölndal, Sweden; 7 AstraZeneca, Alderley Park, Macclesfield, United Kingdom 11:06 544. Non-Contrast-Enhanced High Resolution MRI of the Pulmonary Blood Volume using a Two Compartment Model & T1 Mapping Thomas Gaass 1,2 , Julien Dinkel 3 , Grzegorz Bauman 2 , Moritz Zaiss 2 , Axel Haase 1 , Frederik Laun 2 1 Institute of Medical Engineering, Technical University Munich, Munich, Germany; 2 Division of Medical Physics, German Cancer Research Center, Heidelberg, Germany; 3 Division of Radiology, German Cancer Research Center, Heidelberg, Germany 11:18 545. Pulmonary Blood Volume Mapping using a Modified T1 Weighted, Steady State MRI Technique in a Rodent Model of Hypoxic Pulmonary Vasoconstriction Ronn P. Walvick 1,2 , Austin L. Reno 2 , Alexei A. Bogdanov 2 , Mitchell S. Albert 2 1 2 Radiology, New York University Langone Medical Center, New York, NY, USA; Radiology, University of Massachusetts Medical School, Worcester, MA, USA 78
Thursday <strong>AM</strong> 11:30 546. Acquisition of Spatially-registered Helium-3 & Proton 3D Image Sets of the Lung in Less than 10 Seconds using Compressed Sensing Kun Qing 1 , Talissa A. Altes 2 , Nicholas J. Tustison 2 , Jaime F. Horta Coelho Mata 2 , Grady W. Miller 2,3 , Eduard E. De Lange 2 , William A. Tobias 3 , Gordon D. Cates 3 , James R. Brookeman 2 , John Philip Mugler 1,2 1 2 3 Biomedical Engineering, University of Virginia, Charlottesville, VA, USA; Radiology, University of Virginia; Physics, University of Virginia 11:42 547. Highly Accelerated Dynamic 3D Hyperpolarized Lung Imaging Sebastian Kozerke 1,2 , Salma Ajraoui 3 , Thomas Eykyn 4 , Reza Razavi 4 , Jim M. Wild 3 1 Institute for Biomedical Engineering, University & ETH Zurich, Zurich, Switzerland; 2 Division of Imaging Sciences & Biomedical Engineering, King's College London, London, United Kingdom; 3 Unit of Academic Radiology, University of Sheffield, United Kingdom; 4 Division of Imaging Sciences & Biomedical Engineering, King's College London, United Kingdom 11:54 548. Pulmonary 3 He MRI of Pediatric Subjects with Risk Factors for Asthma Robert V. Cadman 1 , Jionghan Dai 1 , Michael D. Evans 2 , Daniel J. Jackson 3 , James E. Gern 3 , Robert F. Lemanske Jr. 3 , Sean B. Fain 1 1 Medical Physics, University of Wisconsin, Madison, WI, USA; 2 Biostatistics & Medical Informatics, University of Wisconsin, Madison, WI, USA; 3 Pediatrics, University of Wisconsin, Madison, WI, USA 12:06 549. Imaging of Lung Micromechanics with Hyperpolarized Gas Diffusion MRI: Regional Compliance Yi Xin 1 , Kiarash Emami 1 , Stephen J. Kadlecek 1 , Puttisarn Mongkolwisetwara 1 , Nicholas N. Kuzma 1 , Harilla Profka 1 , Yinan Xu 1 , Hooman Hamedani 1 , Benjamin M. Pullinger 1 , Rajat K. Ghosh 1 , Jennia N. Rajaei 1 , Stephen Pickup 1 , Masaru Ishii 2 , Rahim R. Rizi 1 1 2 Radiology, University of Pennsylvania, Philadelphia, PA, USA; Otolaryngology–Head & Neck Surgery, Johns Hopkins University, Baltimore, MD, USA 12:18 550. Quantitative Scoring of Hyperpolarized 129 Xe Ventilation Imaging: Correlation with Pulmonary Function Testing & Age Bastiaan Driehuys 1,2 , Zackary I. Cleveland 2,3 , John Nouls 1,2 , S. Sivaram Kaushik 2,4 , Gary P. Cofer 2 , Santiago Jimenez- Martinez 1 , Jan Wolber 5 , Monica Kraft 6 , H. Page McAdams 1 1 Department of Radiology, Duke University, Durham, NC, USA; 2 Center for in vivo Microscopy, Duke University; 3 Department of Radiology, Duke University, Durham, NC, USA; 4 Biomedical Engineering, Duke University; 5 GE Healthcare; 6 Pulmonary and Critical Care Medicine, Duke University What Went Wrong? A Case-Based Approach to MR Image Quality – Case-Based Teaching Room 516A-C 10:30-12:30 Hosts: Walter F. Block, Derek K. Jones & Chalres A. McKenzie 10:30 “Guess That Artifact” Game Show Cancer Animal Models Room 518-A-C 10:30-12:30 Moderators: Yuen-Li Chung & Robert J. Gillies 10:30 551. Imaging of Glucose Uptake in Breast Tumors using Non-Labeled D-Glucose Kannie Wai Yan Chan 1 , Michael C. McMahon 2 , Guanshu Liu 3 , Yoshinori Kato, Zaver Bhujwalla, Dmitri Artemov, Peter Christiaan van Zijl 1,3 1 Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; 2 F.M. Kirby Research Center, Kennedy Krieger Research Insitute, Baltimore, MD, USA; 3 kennedy Krieger Research Insitute 10:42 552. HGF/SF-Induced Ca+2 Intake to Breast Tumor Cells – a Manganese Enhanced MRI Study Galia Tsarfaty 1 , Ilan Tsarfaty 2 , Sari Natan 2 , Eli Konen 1 , Tammar Kushnir 1 1 Dept. of Diagnostic Imaging, MRI Unit, the Chaim Sheba Medical Center, Tel Hashomer, Israel; 2 Department of Human Microbiology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel 10:54 553. Mapping of Oxygen By Imaging Lipids relaxation Enhancement (MOBILE): Application to Changes in Tumor Oxygenation of Mammary Cancer Models Julie Magat 1 , Elif Ozel 1 , Valérie Marchand 1 , Caroline Bouzin 2 , Olivier Feron 2 , Benedicte F. Jordan 1 , Bernard Gallez 1 1 Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, University of Louvain, Brussels, Belgium; 2 Pole of Pharmacotherapy, University of Louvain, Brussels, Belgium 79
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