Poster <strong>Session</strong>s 138 1 Fraunhofer MEVIS-Institute for Medical Image Computing, Bremen, Germany; 2 Faculty of Physics & Electronics, University of Bremen, Bremen, Germany; 3 Division of Imaging Sciences, Kings's College London, St. Thomas' Hospital, London, United Kingdom; 4 Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard School of Medicine, Boston, MA, United States 1080. Improving the Accuracy & Precision of DCE-MRI Tracer Kinetic Modelling by Imposing Inter-Variable Constraints Leonidas Georgiou 1,2 , Chris James Rose 1,2 1 The University of Manchester Biomedical Imaging Institute, The University of Manchester, Manchester, Greater Manchester, United Kingdom; 2 Manchester Academic Health Science Centre, The University of Manchester, Manchester, Greater Manchester, United Kingdom 1081. Modeling the Effect of Diffusion on the Assessment of K trans & ve in DCE-MRI Stephanie Lynne Barnes 1,2 , John C. Gore 1,2 , Thomas E. Yankeelov 1,2 1 2 Radiology & Radiological Sciences, Vanderbilt University, Nashville, TN, United States; Institute of Imaging Sciences, Vanderbilt University, Nashville, TN, United States 1082. Analysis of DCE-MRI in Oncology: When Should We Use the Tofts Models? Steven Sourbron 1 , David L. Buckley 1 1 Division of Medical Physics, University of Leeds, Leeds, United Kingdom 1083. Quantitative Perfusion MRI of Tumor Model in Mouse Reshmi Rajendran 1 , Jie Ming Liang 1 , Torsten Reese 2 , Hannes Hentze 2 , Susan van Boxtel 2 , Brian Henry 2 , Kai-Hsiang Chuang 1 1 Magnetic Resonance Imaging Group, Laboratory of Molecular Imaging, Singapore Bioimaging Consortium, Singapore, Singapore; 2 Translational Medicine Research Centre, MSD, Singapore 1084. The Assessment of Tumor Cellularity using DSC-MRI Natenael B. Semmineh 1 , Junzhong Xu 1 , John C. Gore 1 , Christopher C. Quarles 1 1 Radiology & Radiological Sciences, Vanderbilt University Institute of Imaging Science, Nashville, TN, United States 1085. Intracellular Water Lifetime Measured by Diffusion Weighted & Dynamic Contrast Enhanced MRI Jin Zhang 1 , Lindsey Decarlo 2 , Robert Schneider 3 , Sungheon Kim 1 1 Center for Biomedical Imaging, Radiology, New York University School of Medicine, New York, United States; 2 Microbiology, New York University School of Medicine, New York, NY, United States; 3 Microbiology, New York University School of Medicine, New York, United States 1086. Comparison of DCE-MRI & Dual Echo DSC-MRI Derived Measures of K trans & v e Christopher Chad Quarles 1 , John Christopher Gore 1 , Thomas Edison Yankeelov 1 1 Radiology & Radiological Sciences, Vanderbilt University, Nashville, TN, United States 1087. Combining Nonlinear Least Squares & Random Forest Regression to Increase the Accuracy & Precision of DCE-MRI Tracer Kinetic Model Parameter Estimates Jakub Palowski 1,2 , Chris James Rose 1,2 1 The University of Manchester Biomedical Imaging Institute, the University of Manchester, Manchester, Greater Manchester, United Kingdom; 2 Manchester Academic Health Science Centre, Tthe University of Manchester, Manchester, Greater Manchester, United Kingdom 1088. The Effects of Platelet-Derived Growth Factor on Vascular Permeability Studied by MRI Yann Jamin 1 , Jessica K. R. Boult 1 , Lauren C. Baker 1 , Simon Walker-Samuel 2 , Arne Östman 3 , Simon P. Robinson 1 1 CRUK & EPSRC Cancer Imaging Centre, The Institute of Cancer Research & Royal Marsden NHS Trust, Sutton, United Kingdom; 2 UCL Centre for Advanced Biomedical Imaging, Department of Medicine & Institute of Child Health, University College London, United Kingdom; 3 Cancer Center Karolinska, Karolinska Institutet, Stockholm, Sweden 1089. Quantitative T 1 & T 2* Assessment of VX 2 Tumour Oxygenation in Response to Hyperoxia & Hypercapnia: Comparison with Invasive Measures & DCE-MRI Jeff D. Winter 1,2 , Margarete K. Akens 3 , Hai-Ling Margaret Margaret Cheng 1,4 1 Physiology & Experimental Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada; 2 Research & Development, IMRIS, Winnipeg, Manitoba, Canada; 3 Orthopaedic Surgery, Sunnybrook Health Sciences, Toronto, Ontario, Canada; 4 Medical Biophysics, University of Toronto, Toronto, Ontario, Canada 1090. Nitrite Induces the Extravasation of Iron Oxide Nanoparticles in C 6 Brain Tumors Nilesh N. Mistry 1 , Jame Van Gambrell 2 , Christopher Chad Quarles 2 1 Dept of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, United States; 2 Dept. of Radiology & Radiological Sciences, Vanderbilt University Institute of Imaging Sciences, Nashville, TN, United States
Poster <strong>Session</strong>s 1091. Tracer-Kinetic Model-Driven Registration Improves Data-Driven Tumour Sub-Segmentation of DCE-MRI Data Giovanni Alessandro Buonaccorsi 1 , Caleb Roberts 1 , James P. B. O'Connor 1 , Chris J. Rose 1 , Susan Cheung 1 , Yvonne Watson 1 , Alan Jackson 2 , Gordon C. Jayson 3 , Geoff J. M. Parker 1 1 ISBE, University of Manchester, Manchester, United Kingdom; 2 WMIC, University of Manchester, Manchester, United Kingdom; 3 Cancer Research UK Dept of Medical Oncology, Christie Hospital, Manchester, United Kingdom 1092. Improved T 1 Quantification using Post-Gd Contrast Variable Flip Angle Data Keiko Miyazaki 1 , James A. d'Arcy 1 , Matthew R. Orton 1 , Dow-Mu Koh 2 , David J. Collins 1 , Martin O. Leach 1 1 CR-UK & EPSRC Cancer Imaging Centre, The Institute of Cancer Research & Royal Marsden Hospital, Sutton, Surrey, United Kingdom; 2 Department of Radiology, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom 1093. Enhanced Perfusion Measurement Accuracy in DCE-MRI Via Improved Baseline Signal Estimation Yiqun Xue 1 , Jiangsheng Yu 1 , Mark A. Rosen 1 , Ramesh Rengan 2 , Hyun Seon Kang 1 , Sarah Englander 1 , Rosemarie Mick 3 , Hee Kwon Song 1 1 Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2 Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, United States; 3 Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, United States 1094. Primed Infusion of Gd.DTPA for Enhanced Imaging of Diffuse Lung Metastasis Tammy Louise Kalber 1,2 , Adrienne E. Campbell 1 , Katy L. Parcell 1 , Bernard M. Siow 1 , Anthony Neil Price 1,3 , Simon Walker-Samuel 1 , Quentin A. Pankhurst 4 , Sam M. Janes 2 , Mark F. Lythgoe 1 1 Centre for Advanced Biomedical Imaging, Division of Medicine & Institute of Child Health, University College London, London, United Kingdom; 2 Centre for Respiratory Research, Department of Medicine, University College London, University College London, London, United Kingdom; 3 Robert Steiner MRI Unit, Imaging Sciences Department, Hammersmith Hospital, Imperial College London, London; 4 Davy-Faraday Research Laboratories, The Royal Institution of Great Britain, London, United Kingdom 1095. Diagnosis of Ovarian Masses with Multi-Parametric Magnetic Resonance Methods: Preliminary Results Jori S. Carter 1 , Navneeth Lakkadi 2 , Jessica E. Kuehn-Hajder 3 , Isabelle V. Iltis 2 , Levi S. Downs, Jr. 1 , Patrick J. Bolan 2 1 Obstetrics, Gynecology, & Women's Health, University of Minnesota, Minneapolis, MN, United States; 2 Radiology/CMRR, University of Minnesota, Minneapolis, MN, United States; 3 Radiology, University of Minnesota, Minneapolis, MN, United States 1096. MR Imaging of Early Stage Uterine Cervical Cancer: Diagnostic Impact of Diffusion-Weighted Imaging & 3D- Dynamic Contrast-Enhanced MRI at 3T Mayumi Takeuchi 1 , Kenji Matsuzaki 1 , Masafumi Harada 1 1 Department of Radiology, University of Tokushima, Tokushima, Japan 1097. Diffusion-Weighted Imaging at 3T for Response Prediction to Chemoradiotherapy in Cervical Cancer Martine I. Dujardin 1 , Abdullah Aldosary 1 , Peter Gibbs 1 , Martin D. Pickles 1 , Lindsay W. Turnbull 1 1 Centre for MR Investigations, University of Hull in association with Hull York Medical School, Hull, East Yorkshire, United Kingdom Articular Cartilage: Quantitative & MRI Analysis Exhibition Hall <strong>Monday</strong> 14:00-16:00 1098. T 1 Quantification in the Cartilage of the Knee with a Modified IR-FSE Technique Gyula Kotek 1 , Marcel J. B. Warntjes 2 , Piotr Wielopolski 1 , Jasper van Tiel 3 , Edwin Oei 1 , Gabriel P. Krestin 1 1 Radiology, Erasmus MC, Rotterdam, Netherlands; 2 Center for Medical Image Science & Visualization (CMIV), Linköping University, Linköping, Sweden; 3 Orthopedics/Radiology, Erasmus MC, Rotterdam, Netherlands 1099. Consistency of T 1ρ Measurements: A Phantom Study Daniel Ross Thedens 1 , Noelle F. Klocke 2 , James A. Martin 2 , Thomas E. Baer 2 , Douglas R. Pedersen 2 1 Radiology, University of Iowa, Iowa City, IA, United States; 2 Orthopaedics & Rehabilitation, University of Iowa 1100. Repeatability of Multi-Component T2* Mapping on Human Knee Cartilages at 3T Yongxian Qian 1 , Ashley A. Williams 2 , Constance R. Chu 2 , Fernando E. Boada 1 1 2 Radiology, University of Pittsburgh, Pittsburgh, PA, United States; Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, United States 1101. Reproducibility of Magnetic Resonance T 1ρ & T 2 Relaxation Time & Morphological Measurements of Articular Hip Cartilage at 3T Alexander Balcar Dillon 1 , Gabby Blumenkrantz Joseph 1 , Xiaojuan Li 1 , Thomas M. Link 1 , Sharmila Majumdar 1 1 Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States 1102. Texture Analysis of T 1ρ Relaxation Times in Knee Osteoarthritis 139
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