12-14 September, 2011, Lucknow - Earth Science India
12-14 September, 2011, Lucknow - Earth Science India
12-14 September, 2011, Lucknow - Earth Science India
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National Conference on <strong>Science</strong> of Climate Change and <strong>Earth</strong>’s Sustainability: Issues and Challenges ‘A Scientist-People Partnership’<br />
<strong>12</strong>-<strong>14</strong> <strong>September</strong>, <strong>2011</strong>, <strong>Lucknow</strong><br />
A GREEN CHEMICAL APPROACH<br />
PHARMACOLOGICAL EVALUATION OF SOME 1, 3, 4-<br />
OXADIAZOLE DERIVATIVES<br />
Khushboo Jain 1* , Bharat Parashar 2 and V.K. Sharma 1**<br />
1 Microwave Chemistry Laboratory, Department of Chemistry, University College of <strong>Science</strong>,<br />
M.L.Sukhadia University, Udaipur (Rajasthan).<br />
2 Department of Pharmaceutical <strong>Science</strong>s, Manav Bharati University, Solan. H.P.<br />
email: * jkhushboo102@gmail.com, ** dr.vinodkumars@yahoo.com<br />
The solvent-free organic reactions assisted by microwaves in particular, have<br />
gained special attention in recent years. The use of microwave irradiation in organic<br />
synthesis can increase the purity of the resulting products, enhance the chemical yield<br />
and shorten the reaction time. Solvent-free reaction leads to a clean, eco-friendly and<br />
economic technology. Reactions on solid support without using solvent usually with<br />
open vessel in domestic microwave ovens are currently in use for synthetic chemist to<br />
create eco-friendly atmosphere. In view of these facts, we present herein a rapid and<br />
efficient method for the synthesis 1, 3, 4-oxadiazoles derivatives in solvent-free<br />
conditions under microwave irradiation using silica gel as solid support. Reaction of<br />
isonicotinohydrazide with different aromatic aldehydes under the microwave irradiation<br />
gives Schiff’s bases. These Schiff’s bases were converted into 1, 3, 4-oxadiazole<br />
derivatives by treating with acetic anhydride under the microwave irradiation. The<br />
structures of the compounds were confirmed by elemental analysis, IR, 1 HNMR and<br />
Mass spectral data. The synthesized compounds were screened for antimicrobial,<br />
analgesic and anti-inflammatory activities.<br />
ON SOME QUALITATIVE ASPECTS OF STOCHASTIC<br />
MODEL ON A DIFFERENTIABLE MANIFOLD: AN<br />
ATMOSPHERIC SCENARIO<br />
Pijush Basak and Arnab Gupta<br />
Narula Institute of Technology, 81 Nilgunj Road, Agarpara, Kolkata 700109<br />
email: pljushbasak@rediffmail.com, arnab.math08@gmail.com<br />
Droughts and floods are two opposite scenario in atmospheric science. Ornstein-<br />
Uhlenbeck process is the stochastic model representing droughts and floods. The main<br />
emphasize in this paper is to study the Stochastic Differential Equation of droughts and<br />
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