Pathology of the Head and Neck
Pathology of the Head and Neck
Pathology of the Head and Neck
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Chapter 6Nasopharynx<strong>and</strong> Waldeyer’s RingS. Regauer6Contents6.1 Embryological Development<strong>of</strong> <strong>the</strong> Nasopharynx <strong>and</strong> Waldeyer’s Ring . . . . . . 1726.2 Nasopharynx . . . . . . . . . . . . . . . . . . . . . . . 1736.2.1 Anatomy <strong>and</strong> Histology . . . . . . . . . . . . . . . . 1736.2.2 Congenital Developmental Anomalies . . . . . . . . 1736.2.2.1 Nasopharyngeal Branchial Cleft Cysts . . . . . . . . 1736.2.2.2 Tornwaldt’s Cyst . . . . . . . . . . . . . . . . . . . . . 1736.2.2.3 Rathke’s Cleft Cyst/Ectopic Pituitary Tissue . . . . 1746.2.2.4 Craniopharyngioma . . . . . . . . . . . . . . . . . . 1746.2.2.5 Heterotopic Brain Tissue/Encephalocele . . . . . . 1746.2.3 Congenital Tumours . . . . . . . . . . . . . . . . . . 1746.2.3.1 Salivary Gl<strong>and</strong> Anlage Tumour . . . . . . . . . . . . 1756.2.3.2 Hairy Polyp . . . . . . . . . . . . . . . . . . . . . . . 1756.2.3.3 Congenital Nasopharyngeal Teratoma . . . . . . . . 1756.2.4 Benign Tumours <strong>and</strong> Tumour-Like Lesions . . . . . 1756.2.4.1 Nasopharyngeal Angi<strong>of</strong>ibroma . . . . . . . . . . . . 1756.2.4.2 Respiratory Epi<strong>the</strong>lialAdenomatoid Hamartoma . . . . . . . . . . . . . . . 1786.2.4.3 Nasopharyngeal Inverted Papilloma . . . . . . . . . 1786.2.4.4 Solitary Fibrous Tumour . . . . . . . . . . . . . . . . 1796.2.4.5 Paraganglioma . . . . . . . . . . . . . . . . . . . . . . 1796.2.4.6 Meningioma . . . . . . . . . . . . . . . . . . . . . . . 1796.2.4.7 Gl<strong>and</strong>ular Retention Cysts . . . . . . . . . . . . . . . 1796.2.5 Nasopharyngeal Carcinoma . . . . . . . . . . . . . . 1806.2.5.1 Non-Keratinising NasopharyngealCarcinoma . . . . . . . . . . . . . . . . . . . . . . . . 1806.2.5.2 Keratinising Nasopharyngeal Carcinoma . . . . . . 1826.2.6 Nasopharyngeal Adenocarcinoma . . . . . . . . . . 1826.2.6.1 Salivary Gl<strong>and</strong>-Type Adenocarcinoma<strong>of</strong> <strong>the</strong> Nasopharynx . . . . . . . . . . . . . . . . . . . 1826.2.6.2 Papillary Adenocarcinoma<strong>of</strong> <strong>the</strong> Nasopharynx . . . . . . . . . . . . . . . . . . . 1826.2.7 Malignant Non-Epi<strong>the</strong>lial Tumours<strong>of</strong> <strong>the</strong> Nasopharynx . . . . . . . . . . . . . . . . . . . 1836.2.7.1 Chordoma . . . . . . . . . . . . . . . . . . . . . . . . 1836.2.7.2 Sarcoma . . . . . . . . . . . . . . . . . . . . . . . . . . 1836.3 Waldeyer’s Ring . . . . . . . . . . . . . . . . . . . . . 1836.3.1 Anatomy <strong>and</strong> Histology <strong>of</strong> Waldeyer’s Ring . . . . . 1836.3.2 Congenital Anomalies <strong>of</strong> Waldeyer’s Ring . . . . . . 1846.3.3 Tonsillitis . . . . . . . . . . . . . . . . . . . . . . . . . 1846.3.3.1 Bacterial Tonsillitis . . . . . . . . . . . . . . . . . . . 1846.3.3.2 Viral Tonsillitis . . . . . . . . . . . . . . . . . . . . . 1856.3.4 Benign Tumours <strong>of</strong> Waldeyer’s Ring . . . . . . . . . 1876.3.4.1 Squamous Papilloma . . . . . . . . . . . . . . . . . . 1876.3.4.2 Lymphangiomatous Tonsillar Polyp . . . . . . . . . 1876.3.5 Carcinomas <strong>of</strong> Waldeyer’s Ring . . . . . . . . . . . . 1876.3.6 Malignant Lymphomas <strong>of</strong> Waldeyer’s Ring . . . . . 1896.3.6.1 Mantle Cell Lymphoma . . . . . . . . . . . . . . . . 1896.3.6.2 Extranodal Marginal Zone B-Cell Lymphoma<strong>of</strong> Mucosa-Associated Lymphoid Tissue . . . . . . . 1906.3.6.3 Extranodal NK/T-Cell Lymphoma,Nasal Type . . . . . . . . . . . . . . . . . . . . . . . . 1906.3.6.4 Hodgkin’s Lymphoma . . . . . . . . . . . . . . . . . 1906.3.6.5 Extramedullary Plasmacytoma . . . . . . . . . . . . 1906.3.7 Systemic Disease Affecting Waldeyer’s Ring . . . . 190References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 191
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