Diagnosis and Management of Infantile Hemangioma

Table 39. Strength of evidence for harms of laser modalities (continued)
Intervention
Surgical
Excision or
Resection
Outcome
Study Design
Quality and Number of
Studies (N Total)
Scarring
Case series: 2 poor 249,251
(142)
Study
Limitations
Consistency Directness Precision
Reporting
Bias
Finding
Strength of Evidence Grade
High Consistent Direct Imprecise NA Scarring in 11/192 children.
Insufficient SOE due to few
occurrences of the outcome
reported in studies.
Wound dehisecence
Case series: 7
poor 238,240,241,243,246,248,251
(483)
High Consistent Direct Imprecise NA Dehiscences in 20/483 children.
Insufficient SOE due to few
occurrences of the outcome
reported in studies with high
limitations.
IH = infantile hemangioma; n = number; NA = not applicable; Nd:YAG = neodymium yttrium aluminium garnet; QoL = quality of life; PDL = pulse dye laser;
RCT = randomized, controlled trial; SOE = strength of evidence
100