Diagnosis and Management of Infantile Hemangioma

Appendix B. Screening and Quality Assessment
Forms
Infantile Hemangioma Abstract Review Form
1. Does this reference include an abstract?
□ Yes □ No □ Cannot Determine
2. Does this study include newborns, infants or children (ages 0-18) with diagnosis of
infantile hemangioma (or suspected hemangioma)?
(Do not include hemangioblastomas, hemangioendothelioma, cavernous
hemangiomas/lesions/malformation, non-involuting congenital hemangiomas (NICH), rapid
involuting congenital hemangiomas (RICH), vascular malformations, choroidal hemangiomas,
diffuse hemangiomatosis, angiomas, verrucous hemangiomas)
□ Yes □ No □ Cannot Determine
3. Is this study original research (e.g., not commentaries, literature reviews, or systematic
reviews, letters to the editor, editorials, case reports)?
□ Yes □ No □ Cannot Determine
4. Does this study address the effectiveness or harms of a diagnostic modality or surgical,
laser or pharmacological intervention for infantile hemangioma?
□ Yes □ No □ Cannot Determine
Diagnostic modality/workup evaluation Including but not limited to:
Diagnostic imaging including MRI, CT, MRA, Echo, Ultrasound
Surgical interventions Including but not limited to: cryotherapy, resection, embolization,
radiofrequency ablation therapy, incisional biopsy
Laser treatment Including but not limited to:
Pulsed dye, fractionated, argon, carbon dioxide, neodymium (Nd): YAG, Erbium lasers
Pharmacologic interventions Including but not limited to:
Beta-blockers (e.g., systemic propranolol, topical timolol); corticosteroids (topical, intralesional,
systemic); sirolimus, imiquimod, interferon, bleomycin, vincristine, ACE inhibitors,
antiangiogenic agents
5. Does this article address contextual questions including natural history, adverse
outcomes of untreated infantile hemangioma, characteristics of the hemangioma that
indicate risk of significant medical complications that would prompt immediate medical or
surgical intervention, or evidence for the association of multiple cutaneous hemangiomas
and increased risk of occult hemangiomas?
□ Yes □ No □ Cannot Determine
Retain for:
□ Background/Discussion □ Review of References □ Other: ____________________
Comments:
B-1