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Diagnosis and Management of Infantile Hemangioma

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• An acute myopathy has been observed with the use <strong>of</strong> high doses<br />

<strong>of</strong> corticosteroids, most <strong>of</strong>ten occurring in patients with disorders <strong>of</strong><br />

neuromuscular transmission (e.g., myasthenia gravis), or in<br />

patients receiving concomitant therapy with neuromuscular<br />

blocking drugs (e.g., pancuronium).<br />

• Corticosteroids may suppress reactions to skin tests.<br />

• Vaccines: Patients on prolonged corticosteroid therapy may exhibit<br />

a diminished response to toxoids <strong>and</strong> live or inactivated vaccines<br />

due to inhibition <strong>of</strong> antibody response. Corticosteroids may also<br />

potentiate the replication <strong>of</strong> some organisms contained in live<br />

attenuated vaccines. Routine administration <strong>of</strong> vaccines or toxoids<br />

should be deferred until corticosteroid therapy is discontinued if<br />

possible<br />

Aristospan®<br />

(triamcinolon<br />

e<br />

hexacetonid<br />

e) 8<br />

Kenalog-<br />

10®<br />

(triamcinolon<br />

e<br />

acetonide) 9<br />

Intralesiona<br />

l injection<br />

The intralesional<br />

administration <strong>of</strong><br />

triamcinolone hexacetonide<br />

injectable suspension is<br />

indicated for:<br />

• alopecia areata<br />

• discoid lupus<br />

erythematosus<br />

• keloids<br />

• localized hypertrophic<br />

• infiltrated<br />

• inflammatory lesions <strong>of</strong><br />

granuloma annulare<br />

• lichen planus<br />

• lichen simplex chronicus<br />

(neurodermatitis)<br />

• psoriatic plaques<br />

• necrobiosis lipoidica<br />

diabeticorum<br />

• cystic tumors <strong>of</strong> an<br />

aponeurosis or tendon<br />

(ganglia)<br />

NOT FOR USE IN<br />

NEWBORNS<br />

Similar Warnings/Precautions the prednisolone with injection specific<br />

warnings in the methylprednisolone row.<br />

Celestone<br />

Soluspan®<br />

(betamethas<br />

one) 10<br />

Intralesiona<br />

l injection<br />

Intralesional injection has<br />

similar indications as listed<br />

in the triamcinolone row.<br />

NOT FOR USE IN<br />

NEWBORNS<br />

Similar Warnings/Precautions the prednisolone with injection specific<br />

warnings in the methylprednisolone row.<br />

H-8

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