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No. 47 (PH 13)
Usefulness of platelet most frequent volume for platelet size evaluation in
thrombocytopenic patients
Setsuki ISONO 1) , Megumi TATSUTA 1) , Keiko NAGATA 1) , Keiko NUMATA 1) , Tosiaki
KOUJITANI 1) , Akiharu OKAMURA 1) , Masahumi TAKATA 2) , Mariko OKANO 3) , Humiko
HATANO 3) , Hiroyasu UEMURA 3) , Takeshi MORISAWA 3) , Masahiko YONETANI 3) , Mariko
TAKENOKUCHI 4) , Katsuyasu SAIGO 4)
1) Department of Laboratory Medicine, Kakogawa West City Hospital, Kakogawa, Hyogo. 2)
Department of Internal Medicine, Kakogawa West City Hospital, Kakogawa, Hyogo. 3) Department of
Pediatrics, Kakogawa West City Hospital, Kakogawa, Hyogo. 4) Faculty of Pharmacological Sciences,
Himeji Dokkyo University, Himeji, Hyogo, Japan
Introduction Platelet size information is helpful for differential diagnosis of the patients with
thrombocytopenia. Although mean platelet volume (MPV) is most frequently employed as platelet
size marker, occasionally MPV cannot be obtained mainly due to severe thrombocytopenia or widely
spread platelet size distribution. Then we have studied the usefulness of platelet most frequent volume
(P-MFV) as a surrogate platelet size marker. Materials and Methods Complete blood counts from
hematologically normal 100 adults, 44 children, 43 newborn infants( birth weight > 2500g) and 23
premature babies (birth weight < 2500g )were enrolled in this study by means of XE-2100 (Sysmex,
Kobe, Japan). They were outpatients or newborn babies in Kakogawa West City Hospital, between May,
2010 and May, 2012. Three patients with acute type immune thrombocytopenia, and one
Wiskott-Aldorich syndrome were also included. Results The correlation efficiency between P-MFV and
MPV was between 0.844 and 0.909 for all populations. P-MFV and MPV correlated very well in any
age group (p