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Program / Abstract Book - KMU WWW3 Server for Education ...

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FO 1<br />

CLINICAL PATHOLOGY SCOPE IN CANCER SURVEILLANCE<br />

Siti Boedina Kresno<br />

Dharmais National Cancer Center,<br />

Jakarta Indonesia<br />

The development of molecular biology gives us a deeper understanding of the mechanism and<br />

pathogenesis of disease and the medical science in the 21 st century will there<strong>for</strong>e be based on the<br />

understanding of disease process at molecular levels. These new trends in the field of oncology<br />

challenges clinical laboratory professionals to provide molecular diagnostic tools.<br />

Cancer surveillance considered <strong>for</strong> this presentation is not monitoring of cancer trends over time or<br />

collecting and analyzing data on cancer occurrence and risk factors at population levels, but in the<br />

context of testing people who are at increased risk <strong>for</strong> developing cancer or have previously had cancer<br />

to predict early recurrence or metastasis.<br />

The scope of clinical pathology in surveillance, prediction and prognostication in cancer includes<br />

hereditary cancer as well as sporadic cancer in particular by using lymphocytes <strong>for</strong> risk assessment of<br />

hereditary cancer and using circulating tumor cells (CTC) and or circulating or cell-free DNA/RNA in<br />

the prognostication of sporadic cancer.<br />

An Indonesian experience in this field will be presented.<br />

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