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Contributors Mats Andersson Microbiology and Tumour Biology Center (MTC) Karolinska Institutet Stockholm, Sweden Frédéric Basyn Center for Numerical Molecular Biophysics Faculté Universitaire des Sciences Agronomiques Gembloux, Belgium Michelle Becker–Hapak Howard Hughes Medical Institute Department of Cellular and Molecular Medicine University of California–San Diego School of Medicine La Jolla, California Michael Bienert Institute of Molecular Pharmacology Berlin, Germany Olivier Bouffioux Center for Numerical Molecular Biophysics Faculté Universitaire des Sciences Agronomiques Gembloux, Belgium Robert Brasseur Center for Numerical Molecular Biophysics Faculté Agronomique Gembloux, Belgium Laurent Chaloin Centre de Recherches de Biochimie Macromoléculaire Biophysics Department Montpellier, France Gilles Divita Centre de Recherches de Biochimie Macromoléculaire Biophysics Department Montpellier, France The Scripps Research Institute Department of Molecular Biology La Jolla, California Steven F. Dowdy Howard Hughes Medical Institute Department of Cellular and Molecular Medicine University of California–San Diego School of Medicine La Jolla, California Edmond Dupont Ecole Normale Supérieure Paris, France Anna Elmquist Department of Neurochemistry and Neurotoxicology Arrhenius Laboratories Stockholm University Stockholm, Sweden L.E. Göran Eriksson Department of Biochemistry and Biophysics Stockholm University Stockholm, Sweden
Liam Good Center for Genomics and Bioinformatics (CGB) Karolinska Institutet Stockholm, Sweden Astrid Gräslund Department of Biochemistry and Biophysics Stockholm University Stockholm, Sweden K.R. Gunaratna Center for Genomics and Bioinformatics (CGB) Karolinska Institutet Stockholm, Sweden Frédéric Heitz Centre de Recherches de Biochimie Macromoléculaire Biophysics Department Montpellier, France Mattias Hällbrink Department of Neurochemistry and Neurotoxicology Arrhenius Laboratories Stockholm University Stockholm, Sweden Alain Joliot Ecole Normale Supérieure Paris, France Erik Kreider CellGate Inc. Sunnyvale, California Ülo Langel Department of Neurochemistry and Neurotoxicology Arrhenius Laboratories Stockholm University Stockholm, Sweden Bernard Lebleu Institut de Génétique Moléculaire Université de Montpellier Montpellier, France Yao-Zhong Lin Department of Microbiology and Immunology Vanderbilt University School of Medicine Nashville, Tennessee Maria Lindgren Department of Neurochemistry and Neurotoxicology Arrhenius Laboratories Stockholm University Stockholm, Sweden May C. Morris Centre de Recherches de Biochimie Macromoléculaire Biophysics Department Montpellier, France The Scripps Research Institute Department of Molecular Biology La Jolla, California Kenta Nakai Human Genome Center The Institute of Medical Science The University of Tokyo Tokyo, Japan Johannes Oehlke Institute of Molecular Pharmacology Berlin, Germany Kanaka Pattabiraman Department of Chemistry Stanford University Stanford, California
Page 2 and 3: CELL- PENETRATING PEPTIDES Processe
Page 4 and 5: Pharmacology and Toxicology: Basic
Page 7 and 8: Library of Congress Cataloging-in-P
Page 9 and 10: to the handbook are prominent resea
Page 11 and 12: REFERENCES 1. Green, M. and Loewens
Page 16 and 17: Erin T. Pelkey Department of Chemis
Page 18 and 19: Contents Section I Classes of Cell-
Page 20: Chapter 16 Cell-Penetrating Peptide
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Page 26 and 27: The Tat-Derived Cell-Penetrating Pe
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42 Cell-Penetrating Peptides: Proce
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3 Transportans Margus Pooga, Mattia
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Transportans 55 Indeed, galparan is
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Transportans 57 especially the endo
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Transportans 59 In the penetration
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Transportans 61 A 21-mer antisense
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Transportans 63 Commonly, the prote
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Transportans 65 antibiotin antibodi
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Transportans 67 For cross-linking o
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Transportans 69 and still retain ef
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Model Amphipathic Peptides 73 its D
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Model Amphipathic Peptides 75 pmol/
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TABLE 4.1 Internalization of Peptid
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TABLE 4.2 Internalization of Peptid
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Model Amphipathic Peptides 81 relat
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Model Amphipathic Peptides 87 A cat
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Model Amphipathic Peptides 89 At th
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Model Amphipathic Peptides 91 16. H
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Signal Sequence-Based Cell-Penetrat
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116 Cell-Penetrating Peptides: Proc
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Interactions of Cell-Penetrating Pe
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Structure Prediction of CPPs and It
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FIGURE 9.7 (Color Figure 9.7 follow
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FIGURE 9.8 The center of the figure
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Biophysical Studies of Cell-Penetra
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Toxicity and Side Effects of Cell-P
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Kinetics of Uptake of Cell-Penetrat
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Cell-Penetrating Peptide Conjugatio
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FIGURE 15.9 (Color Figure 15.9 foll
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Cell-Penetrating Peptides as Vector
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TABLE 16.1 Examples of Transport of
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CPP 2 Cargo or mRNA CAP Antisense A
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Microbial Membrane-Permeating Pepti
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Index A Abaecin, 129 Abz radiolabel
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Index 399 Diffraction, 168 Disulphi
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Index 401 structure prediction, 187
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Index 403 pRB proteins, Tat-E1A bin
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Index 405 lipid perturbation (secon
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