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(Netter Basic Science) Frank H. Netter - Atlas of Human Anatomy-Elsevier (2018)

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Structures With High* Clinical Significance

ANATOMICAL STRUCTURES

CLINICAL IMPORTANCE

NERVOUS SYSTEM—Continued

Visceral pain afferents from

heart

Pain of myocardial ischemia referred to upper thoracic dermatomes; may be perceived as

somatic pain in chest and medial upper limb

PLATE

NUMBERS

231

CARDIOVASCULAR SYSTEM

Internal thoracic artery Commonly used for coronary artery bypass grafts 196, 197

Pulmonary arteries Thromboemboli may obstruct pulmonary vasculature, leading to infarction 205, 210

Pericardium

Coronary arteries

Interventricular septum of

heart

Heart valves

Pericardial effusion (accumulation of fluid or blood) may compromise heart function (cardiac

tamponade)

Atherosclerotic blockage may cause myocardial ischemia and/or infarct; anterior

interventricular (left anterior descending) artery most commonly diseased

Ventricular septal defect is most common congenital cardiac defect; most often involves

membranous part of septum

Congenital variations of valve anatomy or valvular disease (e.g., rheumatic heart disease)

can cause valvular stenosis

Sinuatrial node Aging, previous heart surgery, and some medications can cause cardiac arrhythmias 229

Ligamentum arteriosum

Thoracic aorta

Azygos venous system

LYMPHATIC SYSTEM

Abnormal closure of ductus arteriosus can produce aortic coarctation; lack of closure

produces patent ductus arteriosus; if not closed, may cause exertional dyspnea, pulmonary

vascular disease, or heart failure

Congenital coarctation of aorta can compromise systemic blood flow; collateral vascular

connections can alleviate this condition

Drains posterior thorax and provides important collateral channel between inferior vena cava

and superior vena cava

Mammary gland lymphatics Metastatic spread of cancer cells to axilla and chest via lymphatics draining breast 191

Axillary lymph nodes

Primary nodes that receive lymphatic drainage from upper limb, thoracic wall, and breast;

commonly enlarged in patients with breast cancer

*Selections were based largely on clinical data as well as commonly covered clinical correlations in gross anatomy courses.

215, 219

222

225, 228

226

233

240

241

190, 191

Table 4.2

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Clinical Tables

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