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Microwave Cancer Therapy<br />

Introduction<br />

Electromagnetic heating appears in a wide range of engineering problems and is ideally<br />

suited for modeling in COMSOL Multiphysics because of its multiphysics capabilities.<br />

This example comes from the area of hyperthermic oncology and it models the<br />

electromagnetic field coupled to the bioheat equation. The modeling issues and<br />

techniques are generally applicable to any problem involving electromagnetic heating.<br />

In hyperthermic oncology, cancer is treated by applying localized heating to the tumor<br />

tissue, often in combination with chemotherapy or radiotherapy. Some of the<br />

challenges associated with the selective heating of deep-seated tumors without<br />

damaging surrounding tissue are:<br />

Control of heating power and spatial distribution<br />

Design and placement of temperature sensors<br />

Among possible heating techniques, <strong>RF</strong> and microwave heating have attracted much<br />

attention from clinical researchers. Microwave coagulation therapy is one such<br />

technique where a thin microwave antenna is inserted into the tumor. The microwaves<br />

heat up the tumor, producing a coagulated region where the cancer cells are killed.<br />

This model computes the temperature field, the radiation field, and the specific<br />

absorption rate (SAR)—defined as the ratio of absorbed heat power and tissue<br />

density—in liver tissue when using a thin coaxial slot antenna for microwave<br />

coagulation therapy. It closely follows the analysis found in Ref. 1. It computes the<br />

temperature distribution in the tissue using the bioheat equation.<br />

Model Definition<br />

Figure 3-20 shows the antenna geometry. It consists of a thin coaxial cable with a<br />

ring-shaped slot measuring 1 mm cut on the outer conductor 5 mm from the<br />

short-circuited tip. For hygienic purposes, the antenna is enclosed in a sleeve (catheter)<br />

made of PTFE (polytetrafluoroethylene). The following tables give the relevant<br />

MICROWAVE CANCER THERAPY | 129

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