The Development of Novel Antibiotics Using ... - Jacobs University

[2] WHO World health report 2003. http://www.who.int/whr/en/
[3] J. -M. Lehn, A. V. Eliseev. Dynamic combinatorial chemistry. Science 2001, 291, 2331.
[4] J. -M. Lehn. Dynamic combinatorial chemistry and virtual combinatorial libraries. Chem.
Eur. J. 1999, 5, 2455.
[5] G. Cousins, S. Poulsen, J. Sanders. Dynamic combinatorial libraries of pseudo-peptide
hydrazone macrocycles. Chem. Comm. 1999, 1575.
[6] G. Cousins, R. Furlan, Y. Ng, J. Sanders. Identification and isolation of a receptor for N-
methyl alkylammonium salts: Molecular amplification in a pseudo-peptide dynamic
combinatorial library. Angew. Chem. Int. Ed. 2001, 40, 423.
[7] E. Stulz, Y. Ng, S. Scott, J. Sanders. Amplification of a cyclic mixed-metalloporphyrin
tetramer from a dynamic combinatorial library through orthogonal metal coordination. Chem.
Comm. 2002, 524.
[8] R. Furlan, Y. Ng, S. Otto, J. Sanders. A new cyclic pseudopeptide receptor for Li + from a
dynamic combinatorial library. J. Am. Chem. Soc. 2001, 123, 8876.
[9] S. Otto, R. Furlan, J. Sanders. Selection and amplification of hosts from dynamic
combinatorial libraries of macrocyclic disulfides. Science 2002, 297, 590.
[10] T. Bunyapaiboonsri, O. Ramstrom, S. Lohmann, J. -M. Lehn, L. Peng, M. Goeldner.
Dynamic deconvolution of a pre-equilibrated: Dynamic combinatorial library of
acetylcholinesterase inhibitors. ChemBiochem. 2001, 2, 438.
[11] S.-A. Poulsen. Direct screening of a dynamic combinatorial library using mass
spectrometry. J. Am. Chem. Soc. Mass Spectrom. 2006, 17, 1074.
[12] H. Schiltz, M.-K. Chung, S. Lee, M. Gagńe. The effect of gas-phase reactions on the
quantitation of cyclic hydrazone libraries by electrospray ionization (ESI) mass spectrometry.
Org. Biomol. Chem. 2008, 6, 3597.
[13] B. Liénard, R. Hüting, P. Lassaux, M. Galleni, J.-M. Frère, C. Schofield. Dynamic
combinatorial mass spectrometry leads to metallo-β-lactamase inhibitors. J. Med. Chem. 2008,
51, 684.
[14] S.-A. Poulsen, P. Gates, G. Cousins, J. Sanders. Electrospray ionisation Fourier-transform
ion cyclotron resonance mass spectrometry of dynamic combinatorial libraries. Rapid Comm.
Mass Spectrom. 2000, 14, 44.
[15] C. Hubschwerlen. β-lactam antibiotics. Comprehensive Medicinal Chemistry II
2006, 7, 479.
[16] Y. Nitanai, T. Kikuchi, K. Kakoi, S. Hanamaki, I. Fujisawa, K. Aoki. Crystal structures of
the complexes between Vancomycin and cell-wall precursor analogs. J. Mol. Biol. 2009, 385,
1422.
20 | P a g e