The Development of Novel Antibiotics Using ... - Jacobs University

Table 1. High resolution ESI-TOF/MS data for selective recognition of receptors 7, 9 and 10 to oligopeptide
guests 19 and 20
Host/Guest
Molecular
Formula
a Product Ions Calcd. m/z Meas. m/z Error
[ppm]
(7 and 9)/19 C 44 H 64 N 12 O 19 [(M 9 + M 19 ) + H] + 1065.4483 1065.4499 –1.5
C 42 H 60 N 12 O 17 [(M 7 + M 19 ) + H] + 1005.4272 1005.4309 –3.7
C 65 H 88 N 18 O 27 [(M 7 + M 9 + M 19 ) + H] + 1553.6139 1553.6148 –0.6
C 67 H 92 N 18 O 29 [(2M 9 + M 19 ) + H] + 1613.6350 1613.6363 –0.8
(7 and 9)/20 C 28 H 58 N 10 O 15 [(2M 20 ) + H] + 775.4156 775.4182 –3.3
C 39 H 57 N 11 O 16 [(M 9 + M 20 ) + H] + 936.4058 936.4081 –2.5
C 37 H 53 N 11 O 14 [(M 7 + M 20 ) + H] + 876.3846 876.3880 –3.9
C 58 H 77 N 17 O 22 [(2M 7 + M 20 ) + H] + 1364.5502 1364.5466 2.6
C 62 H 85 N 17 O 26 [(2M 9 + M 20 ) + H] + 1484.5924 1484.5889 2.4
C 60 H 81 N 17 O 24 [(M 7 + M 9 + M 20 ) + H] + 1424.5682 1424.5713 2.2
(7 and 10)/19 C 44 H 66 N 14 O 15 [(M 10 + M 19 ) + H] + 1031.4905 1031.4939 –3.3
(7 and 10)/20 C 39 H 59 N 13 O 12 [(M 10 + M 20 ) + H] + 902.4479 902.4445 3.8
C 37 H 53 N 11 O 14 [(M 7 + M 20 ) + H] + 876.3846 876.3800 5.3
C 32 H 58 N 10 O 12 [(2M 20 ) + H] + 775.4308 775.4305 0.5
(7, 9 and 10)/19 C 44 H 66 N 14 O 15 [(M 10 + M 19 ) + H] + 1031.4905 1031.4897 0.8
C 44 H 64 N 12 O 19 [(M 9 + M 19 ) + H] + 1065.4483 1065.4462 2.0
C 46 H 60 N 16 O 12 [(2M 10 ) + H] + 1029.4649 1029.4696 –4.5
C 46 H 58 N 14 O 16 [(M 9 + M 10 ) + H] + 1063.4228 1063.4250 –2.1
(7, 9 and 10)/20 C 39 H 57 N 11 O 16 [(M 9 + M 20 ) + H] + 936.4058 936.4069 –1.2
C 39 H 59 N 13 O 12 [(M 10 + M 20 ) + H] + 902.4479 902.4520 –4.5
C 37 H 53 N 11 O 14 [(M 7 + M 20 ) + H] + 876.3846 876.3889 –4.9
C 62 H 88 N 19 O 22 [(M 9 + M 10 + M 20 ) + H] + 1450.6346 1450.6369 –1.6
C 62 H 89 N 21 O 18 [(2M 10 + M 20 ) + H] + 1416.6767 1416.6775 –0.6
C 62 H 85 N 17 O 26 [(2M 9 + M 20 ) + H] + 1484.5924 1484.5928 –0.2
a ESI-TOF/MS recorded in the positive ion mode.
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