The Development of Novel Antibiotics Using ... - Jacobs University

Figure 2.4 Trianglimines 10-12 with different cavity sizes ………………………………….. 21
Figure 2.5 Trianglimine 4 forming interlocked structure with β-cyclodextrin 14 ……….…... 22
Figure 2.6 Energy-minimized structure for host/guest complex 4/20 at the MM+ level …….. 23
Figure 2.7 Enantioselective Henry reaction catalyzed by Trianglamine-Cu(OAc) 2 …………. 23
Figure 2.8 Asymmetric hydrosilylation of ketimine 28 ……………………………………… 24
Figure 3.1 Molecular recognition of Vancomycin to D-Ala-D-Ala …………………………. 29
Figure 3.2 C 3 -symmetrical 5 and non-symmetrical 6 trianglimines obtained from 2 ………... 30
Figure 3.3 Modification of the core structure of trianglimine 7 ……………………………... 31
Figure 3.4 Structures of trianglimine 7 and tetra-carbohydrazide cyclophane 10 …………… 32
Figure 3.5 Computed structure for host/guest complex 12/11 at the MM+ level ………..….. 32
Figure 3.6 Macrocycle 13 and receptor 14 which bind with oligopeptides ………………….. 33