The Development of Novel Antibiotics Using ... - Jacobs University

Intens.
[%]
100
903.4
80
60
40
200
500 1000 1500 2000 2500 m/z
Figure 19. ESI-MS 2 for macrocycle 6 in the positive ion mode.
Intens.
[%]
100
80
60
40
20
437.4
463.4
489.3
653.4
OCN
H
N H
N
O N
H
687.4
H 2 N NH
H O
705.3
C 20 H 20 N 6 NaO 6
904.5
463
O
O H
O
0
450 500 550 600 650 700 750 800 850 m/z
Figure 20. Tandem ESI-MS for macrocycle 6 in the positive ion mode.
Intens.
[%]
100
963.5
80
60
40
20
0
500 1000 1500 2000 2500 m/z
Figure 21. ESI-MS 2 for macrocycle 7 in the positive ion mode.
Intens.
[%]
100
80
60
40
20
0
467.4
493.4
519.4
693.4
719.4
745.4
500 550 600 650 700 750 800 850 900 950 m/z
763.4
OCN
O
H
N H
N
O N
H
H 2 N
C 21 H 22 N 6 NaO 7
493
O
NH
H O
O H
O
964.4
Figure 22. Tandem ESI-MS for macrocycle 7 in the positive ion mode.
11